[Music] search for a cancer cure is ongoing but
search for a cancer cure is ongoing but
search for a cancer cure is ongoing but recent research may have given us an
recent research may have given us an
recent research may have given us an edge in the fight welcome to
edge in the fight welcome to
edge in the fight welcome to watchmojo.com will write down news
watchmojo.com will write down news
watchmojo.com will write down news stories that might be on your radar in
stories that might be on your radar in
stories that might be on your radar in this installment we’re counting down 5
this installment we’re counting down 5
this installment we’re counting down 5 need-to-know facts about the ongoing
need-to-know facts about the ongoing
need-to-know facts about the ongoing effort to fight cancer and the T cell
effort to fight cancer and the T cell
effort to fight cancer and the T cell breakthrough number 5 what is T cell
breakthrough number 5 what is T cell
breakthrough number 5 what is T cell cancer therapy research into T cell
cancer therapy research into T cell
cancer therapy research into T cell therapy a form of immunotherapy has been
therapy a form of immunotherapy has been
therapy a form of immunotherapy has been labeled a revolution in humankind’s
labeled a revolution in humankind’s
labeled a revolution in humankind’s battle against cancer well the doctor is
battle against cancer well the doctor is
battle against cancer well the doctor is in with a revolutionary technique that
in with a revolutionary technique that
in with a revolutionary technique that might be their newest tool in the fight
might be their newest tool in the fight
might be their newest tool in the fight against cancer some experts have even
against cancer some experts have even
against cancer some experts have even called immunotherapy the fifth pillar of
called immunotherapy the fifth pillar of
called immunotherapy the fifth pillar of cancer treatment alongside surgery
cancer treatment alongside surgery
cancer treatment alongside surgery chemotherapy radiation and targeted
chemotherapy radiation and targeted
chemotherapy radiation and targeted therapies a new approach which is yet to
therapies a new approach which is yet to
therapies a new approach which is yet to be widely tested the experimental
be widely tested the experimental
be widely tested the experimental treatment works by equipping the body
treatment works by equipping the body
treatment works by equipping the body with modified T cells the type of white
with modified T cells the type of white
with modified T cells the type of white blood cell which can systematically
blood cell which can systematically
blood cell which can systematically attack weak points on a cancerous tumor
attack weak points on a cancerous tumor
attack weak points on a cancerous tumor those weak points called antigens are
those weak points called antigens are
those weak points called antigens are proteins attached to the surface of
proteins attached to the surface of
proteins attached to the surface of cancerous cells and have been described
cancerous cells and have been described
cancerous cells and have been described as cancers Achilles heel as part of the
as cancers Achilles heel as part of the
as cancers Achilles heel as part of the research cancer growth has been compared
research cancer growth has been compared
research cancer growth has been compared to a tree so called branches spread out
to a tree so called branches spread out
to a tree so called branches spread out from a central trunk complicating a
from a central trunk complicating a
from a central trunk complicating a cancerous mass but T cell therapy
cancerous mass but T cell therapy
cancerous mass but T cell therapy targets the trunk aiming to bring down
targets the trunk aiming to bring down
targets the trunk aiming to bring down the branches in turn to comprehensively
the branches in turn to comprehensively
the branches in turn to comprehensively remove any threat number 4 who is
remove any threat number 4 who is
remove any threat number 4 who is leading the cancer research research has
leading the cancer research research has
leading the cancer research research has been an international effort involving
been an international effort involving
been an international effort involving scientists from the UK US Germany and
scientists from the UK US Germany and
scientists from the UK US Germany and Denmark and largely funded by Cancer
Denmark and largely funded by Cancer
Denmark and largely funded by Cancer Research UK dr. Sergio Quezada of
Research UK dr. Sergio Quezada of
Research UK dr. Sergio Quezada of University College London Cancer
University College London Cancer
University College London Cancer Institute described it as the most
Institute described it as the most
Institute described it as the most amazing collaboration he’d ever worked
amazing collaboration he’d ever worked
amazing collaboration he’d ever worked on and Professor Charles Swanton
on and Professor Charles Swanton
on and Professor Charles Swanton co-author of the study published in
co-author of the study published in
co-author of the study published in science and also of UCL explained how
science and also of UCL explained how
science and also of UCL explained how immunotherapy can take personalized
immunotherapy can take personalized
immunotherapy can take personalized medicine to its absolute limit dr.
medicine to its absolute limit dr.
medicine to its absolute limit dr. Stanley Redell is the one credited for
Stanley Redell is the one credited for
Stanley Redell is the one credited for successful early testing as he made
successful early testing as he made
successful early testing as he made headlines in February 2016 when his
headlines in February 2016 when his
headlines in February 2016 when his experimental treatment at Seattle’s Fred
experimental treatment at Seattle’s Fred
experimental treatment at Seattle’s Fred Hutchinson Cancer Research Center blew
Hutchinson Cancer Research Center blew
Hutchinson Cancer Research Center blew unprecedented results for example a
unprecedented results for example a
unprecedented results for example a small group of 29 patients with
small group of 29 patients with
small group of 29 patients with previously incurable or constantly
previously incurable or constantly
previously incurable or constantly in lymphoblastic leukemia underwent
in lymphoblastic leukemia underwent
in lymphoblastic leukemia underwent Rydell’s immune cell therapy and 93%
Rydell’s immune cell therapy and 93%
Rydell’s immune cell therapy and 93% went into complete remission number
went into complete remission number
went into complete remission number three what would be the potential
three what would be the potential
three what would be the potential treatments doctor Quezada has suggested
treatments doctor Quezada has suggested
treatments doctor Quezada has suggested that recent developments could lead to
that recent developments could lead to
that recent developments could lead to two types of treatment customized
two types of treatment customized
two types of treatment customized vaccines or targeted T cell production a
vaccines or targeted T cell production a
vaccines or targeted T cell production a vaccine designed to tackle each
vaccine designed to tackle each
vaccine designed to tackle each individual cancer would represent the
individual cancer would represent the
individual cancer would represent the ultimate personalized form of therapy
ultimate personalized form of therapy
ultimate personalized form of therapy and could yield exceptionally efficient
and could yield exceptionally efficient
and could yield exceptionally efficient results if we’re able to identify the
results if we’re able to identify the
results if we’re able to identify the trunk of any tumor then there’s
trunk of any tumor then there’s
trunk of any tumor then there’s potential for us to vaccinate against
potential for us to vaccinate against
potential for us to vaccinate against the vast majority the second treatment
the vast majority the second treatment
the vast majority the second treatment involves fishing T cells from a patient
involves fishing T cells from a patient
involves fishing T cells from a patient multiplying them outside of the body and
multiplying them outside of the body and
multiplying them outside of the body and then re injecting them for a stronger
then re injecting them for a stronger
then re injecting them for a stronger more effective attack on cancerous cells
more effective attack on cancerous cells
more effective attack on cancerous cells there are drawbacks to both methods
there are drawbacks to both methods
there are drawbacks to both methods however including speed limitations and
however including speed limitations and
however including speed limitations and high expenses number two what was the
high expenses number two what was the
high expenses number two what was the outcome for patients although the new
outcome for patients although the new
outcome for patients although the new treatments are not likely to be widely
treatments are not likely to be widely
treatments are not likely to be widely used for some time initial tests have
used for some time initial tests have
used for some time initial tests have produced encouraging results that’s a
produced encouraging results that’s a
produced encouraging results that’s a really first attempt to determine how
really first attempt to determine how
really first attempt to determine how how widely applicable we can make this
how widely applicable we can make this
how widely applicable we can make this therapy as well as rudel’s ninety-three
therapy as well as rudel’s ninety-three
therapy as well as rudel’s ninety-three percent success rate the researcher also
percent success rate the researcher also
percent success rate the researcher also saw 65% of 30 participants with
saw 65% of 30 participants with
saw 65% of 30 participants with non-hodgkins lymphoma go into remission
non-hodgkins lymphoma go into remission
non-hodgkins lymphoma go into remission in total Redell has treated around 100
in total Redell has treated around 100
in total Redell has treated around 100 patients with the therapy with mostly
patients with the therapy with mostly
patients with the therapy with mostly favorable outcomes
favorable outcomes
favorable outcomes much of the early testing performed by
much of the early testing performed by
much of the early testing performed by Redell and others has been carried out
Redell and others has been carried out
Redell and others has been carried out on patients for whom all other options
on patients for whom all other options
on patients for whom all other options had failed in some cases people have
had failed in some cases people have
had failed in some cases people have been given months to live before
been given months to live before
been given months to live before undergoing immunotherapy and then
undergoing immunotherapy and then
undergoing immunotherapy and then recovered according to doctor Renier J
recovered according to doctor Renier J
recovered according to doctor Renier J Brenton’s of Memorial sloan-kettering
Brenton’s of Memorial sloan-kettering
Brenton’s of Memorial sloan-kettering cancer center in New York and another
cancer center in New York and another
cancer center in New York and another leading figure in the early trials
leading figure in the early trials
leading figure in the early trials results so far are quote proof of
results so far are quote proof of
results so far are quote proof of principle that we can successfully alter
principle that we can successfully alter
principle that we can successfully alter patients T cells so that they attack
patients T cells so that they attack
patients T cells so that they attack their cancer cells number one what does
their cancer cells number one what does
their cancer cells number one what does this mean for the fight against cancer
this mean for the fight against cancer
this mean for the fight against cancer while this is a significant development
while this is a significant development
while this is a significant development and a potentially crucial step forward
and a potentially crucial step forward
and a potentially crucial step forward it’s important to remember that the T
it’s important to remember that the T
it’s important to remember that the T cell immunotherapy breakthrough is not a
cell immunotherapy breakthrough is not a
cell immunotherapy breakthrough is not a cure for cancer yet it’s too early to
cure for cancer yet it’s too early to
cure for cancer yet it’s too early to fully back the treatment which has so
fully back the treatment which has so
fully back the treatment which has so far produced promising results but on a
far produced promising results but on a
far produced promising results but on a small scale
small scale
small scale Charles Swanson has himself underlined
Charles Swanson has himself underlined
Charles Swanson has himself underlined that the research is still in its infant
that the research is still in its infant
that the research is still in its infant we’re not naive he said we know there’s
we’re not naive he said we know there’s
we’re not naive he said we know there’s a long way to go this is the first step
a long way to go this is the first step
a long way to go this is the first step in an exciting journey
in an exciting journey
in an exciting journey however excitement has naturally bred
however excitement has naturally bred
however excitement has naturally bred hope as doctors looked to t cell
hope as doctors looked to t cell
hope as doctors looked to t cell research to potentially save millions of
research to potentially save millions of
research to potentially save millions of lives every year the work of Swanton
lives every year the work of Swanton
lives every year the work of Swanton Quezada Redell and others could still
Quezada Redell and others could still
Quezada Redell and others could still prove to be a false dawn but recent
prove to be a false dawn but recent
prove to be a false dawn but recent trials are sure to be considered a
trials are sure to be considered a
trials are sure to be considered a landmark moment and clear step in the
landmark moment and clear step in the
landmark moment and clear step in the right direction
right direction
right direction did these backs get you thinking to vote
did these backs get you thinking to vote
did these backs get you thinking to vote for which news story is covered next
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