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Here is how we create the artificial skin | Jenna Wong 黃安恩 & Clarissa Yung 容幸之 | TEDxYouth@HongKong


good afternoon everyone my name is

good afternoon everyone my name is Clarissa and I’m Jenna today we’re here

Clarissa and I’m Jenna today we’re here

Clarissa and I’m Jenna today we’re here to tell you the story of our invention

to tell you the story of our invention

to tell you the story of our invention artificial skin let me take you back to

artificial skin let me take you back to

artificial skin let me take you back to the start how exactly that we get from

the start how exactly that we get from

the start how exactly that we get from this to now Jenna do you remember when

this to now Jenna do you remember when

this to now Jenna do you remember when we met yes of course

we met yes of course

we met yes of course we met in kindergarten and we have been

we met in kindergarten and we have been

we met in kindergarten and we have been friends for more than 13 years yeah and

friends for more than 13 years yeah and

friends for more than 13 years yeah and this is a picture of us from when we

this is a picture of us from when we

this is a picture of us from when we were young in primary school it started

were young in primary school it started

were young in primary school it started to mess around and make our own things

to mess around and make our own things

to mess around and make our own things in this picture you see us making or

in this picture you see us making or

in this picture you see us making or trying to make our own pan and we got

trying to make our own pan and we got

trying to make our own pan and we got this idea because of a TV show we watch

this idea because of a TV show we watch

this idea because of a TV show we watch which has something to do with using

which has something to do with using

which has something to do with using blueberry juice and fruit juices to make

blueberry juice and fruit juices to make

blueberry juice and fruit juices to make natural ink yes we were so excited after

natural ink yes we were so excited after

natural ink yes we were so excited after watching a TV show we brought this idea

watching a TV show we brought this idea

watching a TV show we brought this idea back to school and tried it and what you

back to school and tried it and what you

back to school and tried it and what you can see here it was a mess and this was

can see here it was a mess and this was

can see here it was a mess and this was the only mess we made I have memories of

the only mess we made I have memories of

the only mess we made I have memories of us making lotions and perfumes and other

us making lotions and perfumes and other

us making lotions and perfumes and other useful products fast-forward to

useful products fast-forward to

useful products fast-forward to secondary school in 401 we met dr. Alva

secondary school in 401 we met dr. Alva

secondary school in 401 we met dr. Alva dirt a scientist in residence at our

dirt a scientist in residence at our

dirt a scientist in residence at our school at that time he is working on a

school at that time he is working on a

school at that time he is working on a project called algae facial mask and he

project called algae facial mask and he

project called algae facial mask and he asked us we wanted to be a part of that

asked us we wanted to be a part of that

asked us we wanted to be a part of that being the beauty conscious girls that we

being the beauty conscious girls that we

being the beauty conscious girls that we are of course we jumped at this

are of course we jumped at this

are of course we jumped at this opportunity we did some simple

opportunity we did some simple

opportunity we did some simple experiments and learned two major things

experiments and learned two major things

experiments and learned two major things skin Anatomy and skin care the turning

skin Anatomy and skin care the turning

skin Anatomy and skin care the turning point came in 2015 in the summer of 2015

point came in 2015 in the summer of 2015

point came in 2015 in the summer of 2015 there was a powder explosion at high

there was a powder explosion at high

there was a powder explosion at high water park this incident caused many

water park this incident caused many

water park this incident caused many deaths and injuries and a lot of victims

deaths and injuries and a lot of victims

deaths and injuries and a lot of victims suffer from a large area of skin

suffer from a large area of skin

suffer from a large area of skin so we started to think you already had a

so we started to think you already had a

so we started to think you already had a skincare product on our hands well stay

skincare product on our hands well stay

skincare product on our hands well stay away we can modify and change that into

away we can modify and change that into

away we can modify and change that into something that could help the victims we

something that could help the victims we

something that could help the victims we tried to modify our angel mask into an

tried to modify our angel mask into an

tried to modify our angel mask into an artificial skin so what is an artificial

artificial skin so what is an artificial

artificial skin so what is an artificial skin in cases of large area skin loss

skin in cases of large area skin loss

skin in cases of large area skin loss artificial skin can serve as a barrier

artificial skin can serve as a barrier

artificial skin can serve as a barrier layer to protect the one and thus induce

layer to protect the one and thus induce

layer to protect the one and thus induce regeneration of the dermis which is the

regeneration of the dermis which is the

regeneration of the dermis which is the second layer of our skin okay so there

second layer of our skin okay so there

second layer of our skin okay so there is actually a huge demand for artificial

is actually a huge demand for artificial

is actually a huge demand for artificial skin the evidence let’s look at some

skin the evidence let’s look at some

skin the evidence let’s look at some statistics in 2016 there were nearly

statistics in 2016 there were nearly

statistics in 2016 there were nearly 500,000 skin burn cases in the US alone

500,000 skin burn cases in the US alone

500,000 skin burn cases in the US alone and these skin burn cases cost more than

and these skin burn cases cost more than

and these skin burn cases cost more than two hundred thousand US dollars to treat

two hundred thousand US dollars to treat

two hundred thousand US dollars to treat successfully besides many patients

successfully besides many patients

successfully besides many patients suffer from large area of skin loss due

suffer from large area of skin loss due

suffer from large area of skin loss due to other diseases such as diabetes

to other diseases such as diabetes

to other diseases such as diabetes eczema or sunburn with this in mind we

eczema or sunburn with this in mind we

eczema or sunburn with this in mind we started modify our facial masks into an

started modify our facial masks into an

started modify our facial masks into an artificial skin so to begin with our

artificial skin so to begin with our

artificial skin so to begin with our project the first thing we need to do is

project the first thing we need to do is

project the first thing we need to do is to determine the ingredients that is

to determine the ingredients that is

to determine the ingredients that is Venus who have enough formula and

Venus who have enough formula and

Venus who have enough formula and luckily we got 15 ingredients from our

luckily we got 15 ingredients from our

luckily we got 15 ingredients from our facial masks with each Heslin has an own

facial masks with each Heslin has an own

facial masks with each Heslin has an own unique properties that is beneficial to

unique properties that is beneficial to

unique properties that is beneficial to our skin then we narrowed down to 15

our skin then we narrowed down to 15

our skin then we narrowed down to 15 ingredients to two ingredients which is

ingredients to two ingredients which is

ingredients to two ingredients which is sodium alginate and San tanco sodium

sodium alginate and San tanco sodium

sodium alginate and San tanco sodium alginate is extracted from a cell wall

alginate is extracted from a cell wall

alginate is extracted from a cell wall found seaweed and sank as a sugar there

found seaweed and sank as a sugar there

found seaweed and sank as a sugar there are typically from corn and wheat

are typically from corn and wheat

are typically from corn and wheat well with this in mind we started to

well with this in mind we started to

well with this in mind we started to design artificial skin and our design

design artificial skin and our design

design artificial skin and our design has a middle layer a top layer and a

has a middle layer a top layer and a

has a middle layer a top layer and a bottom layer the middle layer is the

bottom layer the middle layer is the

bottom layer the middle layer is the artificial skin and it’s made of sodium

artificial skin and it’s made of sodium

artificial skin and it’s made of sodium alginate and so I think um the top layer

alginate and so I think um the top layer

alginate and so I think um the top layer is a waterproof layer and the bottom

is a waterproof layer and the bottom

is a waterproof layer and the bottom layer oh we have a PowerPoint back yeah

layer oh we have a PowerPoint back yeah

layer oh we have a PowerPoint back yeah and the bottom layer is a calcium

and the bottom layer is a calcium

and the bottom layer is a calcium chloride layer and going back let’s look

chloride layer and going back let’s look

chloride layer and going back let’s look at the definition of artificial skin in

at the definition of artificial skin in

at the definition of artificial skin in cases of large areas of skin nose

cases of large areas of skin nose

cases of large areas of skin nose artificial skin can serve as a barrier

artificial skin can serve as a barrier

artificial skin can serve as a barrier layer to protect the wound and does

layer to protect the wound and does

layer to protect the wound and does induce regeneration of the dermis we

induce regeneration of the dermis we

induce regeneration of the dermis we have also after doing some research we

have also after doing some research we

have also after doing some research we came up with with some criteria of a

came up with with some criteria of a

came up with with some criteria of a good artificial skin well Clarissa can

good artificial skin well Clarissa can

good artificial skin well Clarissa can you name a few

you name a few

you name a few yes it should be a homogeneous hydrogel

yes it should be a homogeneous hydrogel

yes it should be a homogeneous hydrogel and not too adhesive to the wood it

and not too adhesive to the wood it

and not too adhesive to the wood it should also be waterproof and have the

should also be waterproof and have the

should also be waterproof and have the ability to prevent the entry of

ability to prevent the entry of

ability to prevent the entry of microorganisms and hibbott microbial go

microorganisms and hibbott microbial go

microorganisms and hibbott microbial go finally it should keep the wood

finally it should keep the wood

finally it should keep the wood moisturize and absorb fluid effectively

moisturize and absorb fluid effectively

moisturize and absorb fluid effectively and yeah we’re here and putting all all

and yeah we’re here and putting all all

and yeah we’re here and putting all all these letters together and we have

these letters together and we have

these letters together and we have happier

yeah hea fifi i and a and as much and

yeah hea fifi i and a and as much and this is the sign of artificial skin it

this is the sign of artificial skin it

this is the sign of artificial skin it has an artificial skin layer a

has an artificial skin layer a

has an artificial skin layer a waterproof layer and a calcium chloride

waterproof layer and a calcium chloride

waterproof layer and a calcium chloride layer well the first criteria of our

layer well the first criteria of our

layer well the first criteria of our artificial skin is a homogeneous

artificial skin is a homogeneous

artificial skin is a homogeneous hydrogel and this criteria is actually

hydrogel and this criteria is actually

hydrogel and this criteria is actually fulfilled by our two ingredients sodium

fulfilled by our two ingredients sodium

fulfilled by our two ingredients sodium alginate and San tanco a homogeneous

alginate and San tanco a homogeneous

alginate and San tanco a homogeneous hydrogel is a gel that has absorbed a

hydrogel is a gel that has absorbed a

hydrogel is a gel that has absorbed a lot of water and does not have any

lot of water and does not have any

lot of water and does not have any precipitations sodium alginate can

precipitations sodium alginate can

precipitations sodium alginate can immobilize water to form a hydrogel and

immobilize water to form a hydrogel and

immobilize water to form a hydrogel and sand thank gunk as the cement particles

sand thank gunk as the cement particles

sand thank gunk as the cement particles preventing the precipitation of

preventing the precipitation of

preventing the precipitation of ingredients after gel is formed we found

ingredients after gel is formed we found

ingredients after gel is formed we found that the gel is sticky and when thinking

that the gel is sticky and when thinking

that the gel is sticky and when thinking of the application it would be difficult

of the application it would be difficult

of the application it would be difficult and uncomfortable for the user to remove

and uncomfortable for the user to remove

and uncomfortable for the user to remove it from the wood therefore we decided to

it from the wood therefore we decided to

it from the wood therefore we decided to apply four percent calcium chloride

apply four percent calcium chloride

apply four percent calcium chloride solution on to the service of the gel

solution on to the service of the gel

solution on to the service of the gel and due to some chemical bonding

and due to some chemical bonding

and due to some chemical bonding adhesiveness of our artificial skin is

adhesiveness of our artificial skin is

adhesiveness of our artificial skin is reduced we have also developed a

reduced we have also developed a

reduced we have also developed a waterproof layer this waterproof layer

waterproof layer this waterproof layer

waterproof layer this waterproof layer can house to prevent in the irritation

can house to prevent in the irritation

can house to prevent in the irritation caused by bacteria in water so now that

caused by bacteria in water so now that

caused by bacteria in water so now that we’ve introduced you to the basic

we’ve introduced you to the basic

we’ve introduced you to the basic principles of artificial skin we’ll have

principles of artificial skin we’ll have

principles of artificial skin we’ll have a demonstration to show you how it’s

a demonstration to show you how it’s

a demonstration to show you how it’s actually made

so yes start and as mentioned the

so yes start and as mentioned the ingredients we use our sodium alginate

ingredients we use our sodium alginate

ingredients we use our sodium alginate and I think oh and these are the

and I think oh and these are the

and I think oh and these are the ingredients first sodium alginate is

ingredients first sodium alginate is

ingredients first sodium alginate is everything a powder are mixed together

everything a powder are mixed together

everything a powder are mixed together with boiling water until homogeneous

with boiling water until homogeneous

with boiling water until homogeneous hydrogel is formed which is this one and

hydrogel is formed which is this one and

hydrogel is formed which is this one and due to time constraints we’ve already

due to time constraints we’ve already

due to time constraints we’ve already prepared a gel general who now

prepared a gel general who now

prepared a gel general who now demonstrate the remaining steps the

demonstrate the remaining steps the

demonstrate the remaining steps the sodium alginate and xanthan gum solution

sodium alginate and xanthan gum solution

sodium alginate and xanthan gum solution is poor in turn mode and the one we’re

is poor in turn mode and the one we’re

is poor in turn mode and the one we’re using here is made from the 3d printer

using here is made from the 3d printer

using here is made from the 3d printer at our school

and this is to prevent any bumps or

and this is to prevent any bumps or bubbles from forming in the final

bubbles from forming in the final

bubbles from forming in the final product and after you’re satisfied with

product and after you’re satisfied with

product and after you’re satisfied with that calcium chloride can be added and a

that calcium chloride can be added and a

that calcium chloride can be added and a submission this reduces adhesiveness

after that this character fish’s skin

after that this character fish’s skin can be cut out from the mold

and

and that is our product

join us now flipping it to the other

join us now flipping it to the other side to apply more calcium chloride

yeah so that’s our artificial skin and

yeah so that’s our artificial skin and we’ll put it aside for now we’re now

we’ll put it aside for now we’re now

we’ll put it aside for now we’re now demonstrate making the waterproof layer

demonstrate making the waterproof layer

demonstrate making the waterproof layer the waterproof layer is made using

the waterproof layer is made using

the waterproof layer is made using sodium alginate and hydrochloric acid

sodium alginate and hydrochloric acid

sodium alginate and hydrochloric acid and due to higher constraints we’ve

and due to higher constraints we’ve

and due to higher constraints we’ve already prepared the solution the sodium

already prepared the solution the sodium

already prepared the solution the sodium alginate solution is poured into a petri

alginate solution is poured into a petri

alginate solution is poured into a petri dish

and at this point you have to make sure

and at this point you have to make sure you’re being very careful because you

you’re being very careful because you

you’re being very careful because you don’t want any bubbles and bumps

don’t want any bubbles and bumps

don’t want any bubbles and bumps informing and after that is done we can

informing and after that is done we can

informing and after that is done we can add two hydrochloric acid

and that is the first CD of a waterproof

and that is the first CD of a waterproof layer but that actually has to we have

layer but that actually has to we have

layer but that actually has to we have to actually wait five minutes to

to actually wait five minutes to

to actually wait five minutes to adaptive form and we have a finished

adaptive form and we have a finished

adaptive form and we have a finished product here for you to see and this is

product here for you to see and this is

product here for you to see and this is our artificial skin with the waterproof

our artificial skin with the waterproof

our artificial skin with the waterproof layer the artificial skin is the gel

layer the artificial skin is the gel

layer the artificial skin is the gel like thing there and the waterproof

like thing there and the waterproof

like thing there and the waterproof layer is on top and now we’re also

layer is on top and now we’re also

layer is on top and now we’re also distributing samples for you to take a

distributing samples for you to take a

distributing samples for you to take a closer look at so now we will continue

closer look at so now we will continue

closer look at so now we will continue to investigate its properties

to investigate its properties

to investigate its properties now r2p preventing the entry of

now r2p preventing the entry of

now r2p preventing the entry of microorganisms our test results show

microorganisms our test results show

microorganisms our test results show this ability as you can see there are no

this ability as you can see there are no

this ability as you can see there are no black and white spots which are at a

black and white spots which are at a

black and white spots which are at a microbial colonies on the area covered

microbial colonies on the area covered

microbial colonies on the area covered by the artificial skin we have also

by the artificial skin we have also

by the artificial skin we have also tried adding licorice root extracts this

tried adding licorice root extracts this

tried adding licorice root extracts this Chinese helps Tonto

Chinese helps Tonto

Chinese helps Tonto has anti-inflammatory effect and

has anti-inflammatory effect and

has anti-inflammatory effect and encourages the skin to create its own

encourages the skin to create its own

encourages the skin to create its own strengthening connective tissues with

strengthening connective tissues with

strengthening connective tissues with because of the use of sanbanggol in our

because of the use of sanbanggol in our

because of the use of sanbanggol in our formula no precipitate was formed we

formula no precipitate was formed we

formula no precipitate was formed we have also tested the ability to inhibit

have also tested the ability to inhibit

have also tested the ability to inhibit microbial growth after testing we found

microbial growth after testing we found

microbial growth after testing we found that the artificial skin with licorice

that the artificial skin with licorice

that the artificial skin with licorice root extract has this ability we have

root extract has this ability we have

root extract has this ability we have also tested the ability to absorb up to

also tested the ability to absorb up to

also tested the ability to absorb up to of the fluid absorption ability of our

of the fluid absorption ability of our

of the fluid absorption ability of our artificial skin after testing we found

artificial skin after testing we found

artificial skin after testing we found that our artificial skin has a strong

that our artificial skin has a strong

that our artificial skin has a strong fluid absorption and it’s essential for

fluid absorption and it’s essential for

fluid absorption and it’s essential for artificial skin to have a strong

artificial skin to have a strong

artificial skin to have a strong absorption to prevent infection caused

absorption to prevent infection caused

absorption to prevent infection caused by the x-ray from the wood

by the x-ray from the wood

by the x-ray from the wood and these are the major points in our

and these are the major points in our

and these are the major points in our investigation if we were to market our

investigation if we were to market our

investigation if we were to market our product how exactly we represent it well

product how exactly we represent it well

product how exactly we represent it well we hope that it can be packed and

we hope that it can be packed and

we hope that it can be packed and mass-produced in powder form this will

mass-produced in powder form this will

mass-produced in powder form this will extend the shelf life of our product and

extend the shelf life of our product and

extend the shelf life of our product and it allow easy transportation as you can

it allow easy transportation as you can

it allow easy transportation as you can see from our demonstration the

see from our demonstration the

see from our demonstration the production procedures of our artificial

production procedures of our artificial

production procedures of our artificial skin is very easy so when required it

skin is very easy so when required it

skin is very easy so when required it can be freshly prepared quickly and

can be freshly prepared quickly and

can be freshly prepared quickly and without difficulty this can allow the

without difficulty this can allow the

without difficulty this can allow the artificial skin to be tailor-made to

artificial skin to be tailor-made to

artificial skin to be tailor-made to accommodate to each user’s needs well

accommodate to each user’s needs well

accommodate to each user’s needs well we’ve been going on and on about the

we’ve been going on and on about the

we’ve been going on and on about the abilities properties and production

abilities properties and production

abilities properties and production procedures of our artificial skin so how

procedures of our artificial skin so how

procedures of our artificial skin so how exactly is it different from those on

exactly is it different from those on

exactly is it different from those on the market right now

the market right now

the market right now well artificial skin has several

well artificial skin has several

well artificial skin has several benefits first it is made from natural

benefits first it is made from natural

benefits first it is made from natural basic ingredients it is much more BAU

basic ingredients it is much more BAU

basic ingredients it is much more BAU degradable and biocompatible than the

degradable and biocompatible than the

degradable and biocompatible than the existing ones so it can cost it would

existing ones so it can cost it would

existing ones so it can cost it would cost minimal harmful environment after

cost minimal harmful environment after

cost minimal harmful environment after disposal secondly because of the use of

disposal secondly because of the use of

disposal secondly because of the use of 7 governor formula it allowed the

7 governor formula it allowed the

7 governor formula it allowed the addition of extra ingredients it opens

addition of extra ingredients it opens

addition of extra ingredients it opens up the possibility of adding extra

up the possibility of adding extra

up the possibility of adding extra ingredients such as silicon dimethicone

ingredients such as silicon dimethicone

ingredients such as silicon dimethicone other Chinese health that is beneficial

other Chinese health that is beneficial

other Chinese health that is beneficial to our skin and for wound healing and

to our skin and for wound healing and

to our skin and for wound healing and the most important aspects is of course

the most important aspects is of course

the most important aspects is of course cost our product is highly cost

cost our product is highly cost

cost our product is highly cost effective with each meter square only

effective with each meter square only

effective with each meter square only costs 16 Hong Kong dollars it can be

costs 16 Hong Kong dollars it can be

costs 16 Hong Kong dollars it can be easily mass-produced

easily mass-produced

easily mass-produced if this project which joins several

if this project which joins several

if this project which joins several local national and international

local national and international

local national and international competitions if also for our project to

competitions if also for our project to

competitions if also for our project to places like Shanghai and Switzerland and

places like Shanghai and Switzerland and

places like Shanghai and Switzerland and we’ve met a lot of people who’ve given

we’ve met a lot of people who’ve given

we’ve met a lot of people who’ve given us valuable opinions from recessions we

us valuable opinions from recessions we

us valuable opinions from recessions we are defying ideas for further

are defying ideas for further

are defying ideas for further development first we hope to investigate

development first we hope to investigate

development first we hope to investigate more properties of our artificial skin

more properties of our artificial skin

more properties of our artificial skin such as the air permeability who also

such as the air permeability who also

such as the air permeability who also like to develop abilities such as drug

like to develop abilities such as drug

like to develop abilities such as drug delivery finally we hope to incorporate

delivery finally we hope to incorporate

delivery finally we hope to incorporate stem cells and a silhou dermis so there

stem cells and a silhou dermis so there

stem cells and a silhou dermis so there are artificial skin to fully replace a

are artificial skin to fully replace a

are artificial skin to fully replace a damaged dermis yes we still have a long

damaged dermis yes we still have a long

damaged dermis yes we still have a long way to go from ideas into actions dream

way to go from ideas into actions dream

way to go from ideas into actions dream into reality and be impossible and

into reality and be impossible and

into reality and be impossible and supposable ladies and gentlemen today

supposable ladies and gentlemen today

supposable ladies and gentlemen today are to believe and prepare to achieve

are to believe and prepare to achieve

are to believe and prepare to achieve thank you

thank you

thank you [Applause]

”

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