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Why Mom and Dad Make Us Who We Are | Valter Tucci | TEDxUniversityOfSanFrancisco


good evening

good evening so I’m a behavioral scientist and

so I’m a behavioral scientist and

so I’m a behavioral scientist and tonight I want to tell you a story

imagine a country which is a big

imagine a country which is a big producer of oil which by the way is a

producer of oil which by the way is a

producer of oil which by the way is a limited product this country has to

limited product this country has to

limited product this country has to provide oil for all inland consumers

provide oil for all inland consumers

provide oil for all inland consumers which is important this determines the

which is important this determines the

which is important this determines the welfare of the consumers and eventually

welfare of the consumers and eventually

welfare of the consumers and eventually the welfare of the population imagine

the welfare of the population imagine

the welfare of the population imagine now that out there there is a market

now that out there there is a market

now that out there there is a market which is made by private entities which

which is made by private entities which

which is made by private entities which are driven by the goal of making money

are driven by the goal of making money

are driven by the goal of making money out of the oil trading our country will

out of the oil trading our country will

out of the oil trading our country will have to face a big dilemma whether to

have to face a big dilemma whether to

have to face a big dilemma whether to use internal local oil or whether to

use internal local oil or whether to

use internal local oil or whether to assess to the international market and

assess to the international market and

assess to the international market and try to get oil for the consumers from

try to get oil for the consumers from

try to get oil for the consumers from external sources the solution to this

external sources the solution to this

external sources the solution to this dilemma looks quite obvious indeed each

dilemma looks quite obvious indeed each

dilemma looks quite obvious indeed each use of internal oil local oil will have

use of internal oil local oil will have

use of internal oil local oil will have a long-term cost for the conferral

a long-term cost for the conferral

a long-term cost for the conferral consumers instead if this country is a

consumers instead if this country is a

consumers instead if this country is a implements a policy of importing oil

implements a policy of importing oil

implements a policy of importing oil from external sources this will increase

from external sources this will increase

from external sources this will increase on the long term this enviable

on the long term this enviable

on the long term this enviable of the consumers so I mean a benefit for

of the consumers so I mean a benefit for

of the consumers so I mean a benefit for the population now the example I just

the population now the example I just

the population now the example I just made is not the introduction to a TED

made is not the introduction to a TED

made is not the introduction to a TED talk in geopolitics it is instead the

talk in geopolitics it is instead the

talk in geopolitics it is instead the introduction to genetics the producers

introduction to genetics the producers

introduction to genetics the producers in this case are the parents and in

in this case are the parents and in

in this case are the parents and in particular demand according to the

particular demand according to the

particular demand according to the example I will talk about tonight the

example I will talk about tonight the

example I will talk about tonight the consumers are the offspring newborns

consumers are the offspring newborns

consumers are the offspring newborns individuals of our species which I will

individuals of our species which I will

individuals of our species which I will define

define

define altricial which means that their

altricial which means that their

altricial which means that their survival depends very much on the

survival depends very much on the

survival depends very much on the caregiver at least for some period of

caregiver at least for some period of

caregiver at least for some period of time after birth until winning a decent

time after birth until winning a decent

time after birth until winning a decent brief is also the an introduction to a

brief is also the an introduction to a

brief is also the an introduction to a framework of an evolutionary theory

framework of an evolutionary theory

framework of an evolutionary theory proposed by David Icke an evolutionary

proposed by David Icke an evolutionary

proposed by David Icke an evolutionary biologist at Harvard who states that mum

biologist at Harvard who states that mum

biologist at Harvard who states that mum is very much focused in maximizing the

is very much focused in maximizing the

is very much focused in maximizing the survival of all offspring and therefore

survival of all offspring and therefore

survival of all offspring and therefore what she will try to do

what she will try to do

what she will try to do is to budget as much as possible or all

is to budget as much as possible or all

is to budget as much as possible or all air resources and so that she can invest

air resources and so that she can invest

air resources and so that she can invest more in all offspring and in doing that

more in all offspring and in doing that

more in all offspring and in doing that she will use different strategies one of

she will use different strategies one of

she will use different strategies one of this strategy might be the anticipation

this strategy might be the anticipation

this strategy might be the anticipation of winning so that she can save some

of winning so that she can save some

of winning so that she can save some resources and get dad more involved in

resources and get dad more involved in

resources and get dad more involved in the care of the offspring from a recent

the care of the offspring from a recent

the care of the offspring from a recent lecture title a tale of two mothers we

lecture title a tale of two mothers we

lecture title a tale of two mothers we can make few considerations few

can make few considerations few

can make few considerations few observations but just looking at the

observations but just looking at the

observations but just looking at the reproductive strategies of female

reproductive strategies of female

reproductive strategies of female chimpanzees versus women of our species

chimpanzees versus women of our species

chimpanzees versus women of our species indeed if you look at this graph female

indeed if you look at this graph female

indeed if you look at this graph female chimpanzees give a birth quite early in

chimpanzees give a birth quite early in

chimpanzees give a birth quite early in life at the age of 12 15 they can’t

life at the age of 12 15 they can’t

life at the age of 12 15 they can’t reproduce until the end of their life

reproduce until the end of their life

reproduce until the end of their life with almost no post reproductive period

with almost no post reproductive period

with almost no post reproductive period if you think about basically species

if you think about basically species

if you think about basically species occupy most of the life time for

occupy most of the life time for

occupy most of the life time for reproduction

reproduction

reproduction moreover chimpanzee win quite late in

moreover chimpanzee win quite late in

moreover chimpanzee win quite late in life they win at the age of five or

life they win at the age of five or

life they win at the age of five or Angleton even later at the age of seven

Angleton even later at the age of seven

Angleton even later at the age of seven eight and the female chimpanzee won’t

eight and the female chimpanzee won’t

eight and the female chimpanzee won’t become pregnant again until the previous

become pregnant again until the previous

become pregnant again until the previous offspring is not fully independent

offspring is not fully independent

offspring is not fully independent instead if you look at how our species

instead if you look at how our species

instead if you look at how our species we can see that women give birth quite

we can see that women give birth quite

we can see that women give birth quite late in life an average of age of twenty

late in life an average of age of twenty

late in life an average of age of twenty but even a later this change across

but even a later this change across

but even a later this change across different cultures and we have a very

different cultures and we have a very

different cultures and we have a very long post reproductive period humans can

long post reproductive period humans can

long post reproductive period humans can win quite early instead and we win at

win quite early instead and we win at

win quite early instead and we win at the age of two three so that basically

the age of two three so that basically

the age of two three so that basically we have a multiple births quite close

we have a multiple births quite close

we have a multiple births quite close each other and this is a good strategy

each other and this is a good strategy

each other and this is a good strategy in order to use only a small segment of

in order to use only a small segment of

in order to use only a small segment of our lifetime dedicated to reproduction

our lifetime dedicated to reproduction

our lifetime dedicated to reproduction so what is all this telling us well

so what is all this telling us well

so what is all this telling us well first of all tells us that we are a

first of all tells us that we are a

first of all tells us that we are a species compared to other great apes

species compared to other great apes

species compared to other great apes that is capable of winning immature

that is capable of winning immature

that is capable of winning immature offspring individuals that not fully

offspring individuals that not fully

offspring individuals that not fully developed yet and if you think about

developed yet and if you think about

developed yet and if you think about this is mirrors exactly the way our

this is mirrors exactly the way our

this is mirrors exactly the way our societies organized

societies organized

societies organized indeed women can delegate the care of

indeed women can delegate the care of

indeed women can delegate the care of the offspring to fathers to grandparents

the offspring to fathers to grandparents

the offspring to fathers to grandparents to nurseries quite often to a

to nurseries quite often to a

to nurseries quite often to a combination of all these and these are

combination of all these and these are

combination of all these and these are some advantages for example as I said

some advantages for example as I said

some advantages for example as I said before we can use only a small segment

before we can use only a small segment

before we can use only a small segment of our life for the production but this

of our life for the production but this

of our life for the production but this allowed also to carry multiple offspring

allowed also to carry multiple offspring

allowed also to carry multiple offspring at the same time however this has some

at the same time however this has some

at the same time however this has some disadvantage for potentially

disadvantage for potentially

disadvantage for potentially disadvantages for the offspring indeed

disadvantages for the offspring indeed

disadvantages for the offspring indeed this increases the level of the risk for

this increases the level of the risk for

this increases the level of the risk for dr. King and what I will harbour in a

dr. King and what I will harbour in a

dr. King and what I will harbour in a moment that when this is match with

moment that when this is match with

moment that when this is match with particularly genetic factor might have

particularly genetic factor might have

particularly genetic factor might have negative consequences in life but better

negative consequences in life but better

negative consequences in life but better back to biology which are these genetic

back to biology which are these genetic

back to biology which are these genetic factors where there are specific genes

factors where there are specific genes

factors where there are specific genes which regulate all these mechanisms and

which regulate all these mechanisms and

which regulate all these mechanisms and what I would like to do tonight is to

what I would like to do tonight is to

what I would like to do tonight is to talk about a particular class of genes

talk about a particular class of genes

talk about a particular class of genes called imprinted genes what is the

called imprinted genes what is the

called imprinted genes what is the genomic imprinting genomic imprinting is

genomic imprinting genomic imprinting is

genomic imprinting genomic imprinting is an epigenetic phenomenon which regards

an epigenetic phenomenon which regards

an epigenetic phenomenon which regards only a small set of genes and in this

only a small set of genes and in this

only a small set of genes and in this particular case it sets on and off only

particular case it sets on and off only

particular case it sets on and off only one copy of a gene either if this copy

one copy of a gene either if this copy

one copy of a gene either if this copy is inherited from the maternal line or

is inherited from the maternal line or

is inherited from the maternal line or if the copy is inherited from the

if the copy is inherited from the

if the copy is inherited from the paternal line and in some case the

paternal line and in some case the

paternal line and in some case the maternal copy is a silence so that gene

maternal copy is a silence so that gene

maternal copy is a silence so that gene is paternal expressed in other case is

is paternal expressed in other case is

is paternal expressed in other case is the paternal copy that is silenced that

the paternal copy that is silenced that

the paternal copy that is silenced that gene is maternal express so these genes

gene is maternal express so these genes

gene is maternal express so these genes are expressed differentially expressed

are expressed differentially expressed

are expressed differentially expressed in different part of our organism for

in different part of our organism for

in different part of our organism for example they are highly expressing the

example they are highly expressing the

example they are highly expressing the placenta and interesting enough for us

placenta and interesting enough for us

placenta and interesting enough for us that we study behavior they are highly

that we study behavior they are highly

that we study behavior they are highly expressed in the brain but why are so

expressed in the brain but why are so

expressed in the brain but why are so important well we know that imprinted

important well we know that imprinted

important well we know that imprinted genes are extremely important during

genes are extremely important during

genes are extremely important during development they regulate for example

development they regulate for example

development they regulate for example growth neural development but they’re

growth neural development but they’re

growth neural development but they’re also important for the setting of many

also important for the setting of many

also important for the setting of many behavioral aspects early in life and

behavioral aspects early in life and

behavioral aspects early in life and also for many metabolic expect for

also for many metabolic expect for

also for many metabolic expect for example imprinted genes are in poor

example imprinted genes are in poor

example imprinted genes are in poor and in regulating the capability of the

and in regulating the capability of the

and in regulating the capability of the offspring to take resources from the

offspring to take resources from the

offspring to take resources from the mother and also to they participate in

mother and also to they participate in

mother and also to they participate in the regulation of the interpreter well

the regulation of the interpreter well

the regulation of the interpreter well so the interval between distant birth is

so the interval between distant birth is

so the interval between distant birth is extremely important indeed if you are an

extremely important indeed if you are an

extremely important indeed if you are an offspring this tells you how long your

offspring this tells you how long your

offspring this tells you how long your mom would be able to invest in you

mom would be able to invest in you

mom would be able to invest in you before you will be sharing resources

before you will be sharing resources

before you will be sharing resources with the next offspring and trust me on

with the next offspring and trust me on

with the next offspring and trust me on this data was last in line my family so

this data was last in line my family so

this data was last in line my family so I know this very well but besides all

I know this very well but besides all

I know this very well but besides all these aspects we know that the genomic

these aspects we know that the genomic

these aspects we know that the genomic imprinting plays an important role we

imprinting plays an important role we

imprinting plays an important role we just discovered recently in one of the

just discovered recently in one of the

just discovered recently in one of the most mysterious aspect of our life which

most mysterious aspect of our life which

most mysterious aspect of our life which is still not fully understood this is

is still not fully understood this is

is still not fully understood this is asleep in my lab we discover that a few

asleep in my lab we discover that a few

asleep in my lab we discover that a few imprinted genes regulate one specific

imprinted genes regulate one specific

imprinted genes regulate one specific form of sleep which is called

form of sleep which is called

form of sleep which is called REM sleep so what is REM sleep REM is a

REM sleep so what is REM sleep REM is a

REM sleep so what is REM sleep REM is a physiologically active form of sleep in

physiologically active form of sleep in

physiologically active form of sleep in which our eyes move very fast and in

which our eyes move very fast and in

which our eyes move very fast and in which we experience dreaming but it

which we experience dreaming but it

which we experience dreaming but it turns out that the RAM is also very

turns out that the RAM is also very

turns out that the RAM is also very important during development and in

important during development and in

important during development and in particularly if you look at the

particularly if you look at the

particularly if you look at the developmental phase we see that the

developmental phase we see that the

developmental phase we see that the predominant state in this place is sleep

predominant state in this place is sleep

predominant state in this place is sleep more than 95% of the time of a fetus to

more than 95% of the time of a fetus to

more than 95% of the time of a fetus to spend a sleep and also after birth

spend a sleep and also after birth

spend a sleep and also after birth newborns spend most of their time in

newborns spend most of their time in

newborns spend most of their time in sleep and all this sleep is made by REM

sleep and all this sleep is made by REM

sleep and all this sleep is made by REM sleep which is also important for

sleep which is also important for

sleep which is also important for reproductive success later in life

reproductive success later in life

reproductive success later in life indeed if we block REM sleep during

indeed if we block REM sleep during

indeed if we block REM sleep during development we might lead to sexual

development we might lead to sexual

development we might lead to sexual dysfunction and to brain dysfunction all

dysfunction and to brain dysfunction all

dysfunction and to brain dysfunction all sort of conditions which reduces the

sort of conditions which reduces the

sort of conditions which reduces the reproductive opportunity for the

reproductive opportunity for the

reproductive opportunity for the individual but we know that REM is also

individual but we know that REM is also

individual but we know that REM is also extremely important for the

extremely important for the

extremely important for the establishment of many behavioral aspects

establishment of many behavioral aspects

establishment of many behavioral aspects during early life and what I will argue

during early life and what I will argue

during early life and what I will argue tonight that is important for attachment

tonight that is important for attachment

tonight that is important for attachment my friend Patrick McNamara professor at

my friend Patrick McNamara professor at

my friend Patrick McNamara professor at Boston University back in 2004 predicted

Boston University back in 2004 predicted

Boston University back in 2004 predicted that genomic imprinting was important

that genomic imprinting was important

that genomic imprinting was important for sleep and also that sleep is

for sleep and also that sleep is

for sleep and also that sleep is important in setting the bonding between

important in setting the bonding between

important in setting the bonding between the newborns and the mother he suggested

the newborns and the mother he suggested

the newborns and the mother he suggested the REM sleep could be profound

the REM sleep could be profound

the REM sleep could be profound in reinforcing the attachment with the

in reinforcing the attachment with the

in reinforcing the attachment with the caregiver and there are quite few

caregiver and there are quite few

caregiver and there are quite few research evidence showing this and going

research evidence showing this and going

research evidence showing this and going this direction for example we know that

this direction for example we know that

this direction for example we know that RAM increases when newborns

RAM increases when newborns

RAM increases when newborns cause sleep with the mothers conversely

cause sleep with the mothers conversely

cause sleep with the mothers conversely Ram decreases during maternal separation

Ram decreases during maternal separation

Ram decreases during maternal separation and there are several mechanism along

and there are several mechanism along

and there are several mechanism along with the sleep and with lactation which

with the sleep and with lactation which

with the sleep and with lactation which dictate the time for the next birth of

dictate the time for the next birth of

dictate the time for the next birth of the offspring also we know that the REM

the offspring also we know that the REM

the offspring also we know that the REM sleep changed across different species

sleep changed across different species

sleep changed across different species and he seems to be strongly correlated

and he seems to be strongly correlated

and he seems to be strongly correlated with the alt reality of a species so the

with the alt reality of a species so the

with the alt reality of a species so the greater is the maturity of a species the

greater is the maturity of a species the

greater is the maturity of a species the longer the time they spent asleep

longer the time they spent asleep

longer the time they spent asleep for example ferrets which are born in a

for example ferrets which are born in a

for example ferrets which are born in a quiet immature state days have almost 30

quiet immature state days have almost 30

quiet immature state days have almost 30 percent of their sleep in RAM while more

percent of their sleep in RAM while more

percent of their sleep in RAM while more precocial species like or PSA’s they

precocial species like or PSA’s they

precocial species like or PSA’s they spend only 20% of the sleep time in RAM

spend only 20% of the sleep time in RAM

spend only 20% of the sleep time in RAM and humans were just ended in between

and humans were just ended in between

and humans were just ended in between both in terms of a few allottee and

both in terms of a few allottee and

both in terms of a few allottee and expression of REM sleep so but what’s

expression of REM sleep so but what’s

expression of REM sleep so but what’s going on in the brain during REM sleep

going on in the brain during REM sleep

going on in the brain during REM sleep well a number of things going on in the

well a number of things going on in the

well a number of things going on in the brain and outside brain when we enter

brain and outside brain when we enter

brain and outside brain when we enter REM sleep during this physiological

REM sleep during this physiological

REM sleep during this physiological state we we lose for example the control

state we we lose for example the control

state we we lose for example the control of our body temperature so it’s a sort

of our body temperature so it’s a sort

of our body temperature so it’s a sort of going back in evolution down to the

of going back in evolution down to the

of going back in evolution down to the reptile lineage if you wish but there

reptile lineage if you wish but there

reptile lineage if you wish but there also many brain areas which are

also many brain areas which are

also many brain areas which are activated during REM sleep and one of

activated during REM sleep and one of

activated during REM sleep and one of these is the MiG da amygdala is an

these is the MiG da amygdala is an

these is the MiG da amygdala is an extremely important structure for our

extremely important structure for our

extremely important structure for our brain it provides us the capability to

brain it provides us the capability to

brain it provides us the capability to process emotions and when you are child

process emotions and when you are child

process emotions and when you are child this is extremely important it provides

this is extremely important it provides

this is extremely important it provides you the right infrastructure to

you the right infrastructure to

you the right infrastructure to understand if the environment around you

understand if the environment around you

understand if the environment around you is safe or not weather is chaotic or is

is safe or not weather is chaotic or is

is safe or not weather is chaotic or is predictable it has been shown that if

predictable it has been shown that if

predictable it has been shown that if the local environment during the first

the local environment during the first

the local environment during the first year of life is not stable and

year of life is not stable and

year of life is not stable and predictable this may have dramatic

predictable this may have dramatic

predictable this may have dramatic consequences for the developmental

consequences for the developmental

consequences for the developmental trajectories of the

trajectories of the

trajectories of the individuals so affecting the rest of our

individuals so affecting the rest of our

individuals so affecting the rest of our life so all this brings us to the next

life so all this brings us to the next

life so all this brings us to the next topic which motivated part of our

topic which motivated part of our

topic which motivated part of our research over the last few years and

research over the last few years and

research over the last few years and particularly what we wonder was what’s

particularly what we wonder was what’s

particularly what we wonder was what’s going on when we change genetic

going on when we change genetic

going on when we change genetic background and we discover that a

background and we discover that a

background and we discover that a combination a particular combination of

combination a particular combination of

combination a particular combination of maternal and paternal genes affects the

maternal and paternal genes affects the

maternal and paternal genes affects the expression of REM sleep but also the

expression of REM sleep but also the

expression of REM sleep but also the interaction between the newborns and the

interaction between the newborns and the

interaction between the newborns and the mother and what I will hug you here that

mother and what I will hug you here that

mother and what I will hug you here that influenced the development of particular

influenced the development of particular

influenced the development of particular attachment style what we did in this

attachment style what we did in this

attachment style what we did in this experiment is to subject newborn mice to

experiment is to subject newborn mice to

experiment is to subject newborn mice to an unfamiliar female and later to the

an unfamiliar female and later to the

an unfamiliar female and later to the man and we study how they react when in

man and we study how they react when in

man and we study how they react when in the explore the in unfamiliar

the explore the in unfamiliar

the explore the in unfamiliar environment and then during the reunion

environment and then during the reunion

environment and then during the reunion and what we understood is that a

and what we understood is that a

and what we understood is that a particular set of maternal and paternal

particular set of maternal and paternal

particular set of maternal and paternal genes influence this behavior in

genes influence this behavior in

genes influence this behavior in particular responsible of which

particular responsible of which

particular responsible of which developmental which attachment style the

developmental which attachment style the

developmental which attachment style the mouse will develop whether will have a

mouse will develop whether will have a

mouse will develop whether will have a secure attachment or an insecure

secure attachment or an insecure

secure attachment or an insecure attachment and most important this

attachment and most important this

attachment and most important this influence also the behavior as adult

influence also the behavior as adult

influence also the behavior as adult indeed those mice which develop an

indeed those mice which develop an

indeed those mice which develop an insecure attachment later in life will

insecure attachment later in life will

insecure attachment later in life will interact less and less with other

interact less and less with other

interact less and less with other conspecific so showing a sort of a

conspecific so showing a sort of a

conspecific so showing a sort of a social impairment so all I told you

social impairment so all I told you

social impairment so all I told you today brings us to some important

today brings us to some important

today brings us to some important consideration first of all that humans

consideration first of all that humans

consideration first of all that humans are not fully dedicated to the

are not fully dedicated to the

are not fully dedicated to the production we are not mandatorily

production we are not mandatorily

production we are not mandatorily committed to just pass our genes on to

committed to just pass our genes on to

committed to just pass our genes on to the next generation we surely respond to

the next generation we surely respond to

the next generation we surely respond to this evolutionary need but we have

this evolutionary need but we have

this evolutionary need but we have organized also our life with plenty of

organized also our life with plenty of

organized also our life with plenty of time to develop other activities and not

time to develop other activities and not

time to develop other activities and not all these activities are engaged in

all these activities are engaged in

all these activities are engaged in specific revolutionary programs compared

specific revolutionary programs compared

specific revolutionary programs compared to our other primates we extended our

to our other primates we extended our

to our other primates we extended our apostle productive period but we also

apostle productive period but we also

apostle productive period but we also extended our juvenile period and in

extended our juvenile period and in

extended our juvenile period and in particular during this extended juvenile

particular during this extended juvenile

particular during this extended juvenile period

period

period we invest lots of resources in preparing

we invest lots of resources in preparing

we invest lots of resources in preparing ourself for adult life this is called

ourself for adult life this is called

ourself for adult life this is called education which occurs generally in

education which occurs generally in

education which occurs generally in families but also mostly in a social

families but also mostly in a social

families but also mostly in a social context and we also create a specialized

context and we also create a specialized

context and we also create a specialized organization for that which are called

organization for that which are called

organization for that which are called school another important consideration

school another important consideration

school another important consideration we can take from here that we are a

we can take from here that we are a

we can take from here that we are a species that is capable of sharing the

species that is capable of sharing the

species that is capable of sharing the responsibility of the safety of our

responsibility of the safety of our

responsibility of the safety of our children within the social context and

children within the social context and

children within the social context and hold these aspects are extremely

hold these aspects are extremely

hold these aspects are extremely important and this should improve the

important and this should improve the

important and this should improve the quality of our life

quality of our life

quality of our life so the next question is is this what

so the next question is is this what

so the next question is is this what really happening unfortunately things

really happening unfortunately things

really happening unfortunately things don’t go always in this direction for

don’t go always in this direction for

don’t go always in this direction for example psychological suffering

example psychological suffering

example psychological suffering represents a tremendous burden for our

represents a tremendous burden for our

represents a tremendous burden for our society it has been estimated that 350

society it has been estimated that 350

society it has been estimated that 350 million individuals suffer from

million individuals suffer from

million individuals suffer from depression around the world and

depression around the world and

depression around the world and depression is some case may lead to

depression is some case may lead to

depression is some case may lead to suicide has been estimated at 800,000

suicide has been estimated at 800,000

suicide has been estimated at 800,000 individuals every year commit suicide an

individuals every year commit suicide an

individuals every year commit suicide an average of one individual every 40

average of one individual every 40

average of one individual every 40 seconds in psychological suffering is

seconds in psychological suffering is

seconds in psychological suffering is caused not only by depression but also

caused not only by depression but also

caused not only by depression but also for example by personality disorders 10%

for example by personality disorders 10%

for example by personality disorders 10% of u.s. population suffers personality

of u.s. population suffers personality

of u.s. population suffers personality disorders and those are disorders we

disorders and those are disorders we

disorders and those are disorders we affect which affect not only the

affect which affect not only the

affect which affect not only the individual but also families the partner

individual but also families the partner

individual but also families the partner the social context aim of the working

the social context aim of the working

the social context aim of the working environment so if you wish is a sort of

environment so if you wish is a sort of

environment so if you wish is a sort of epidemic effort across the society in a

epidemic effort across the society in a

epidemic effort across the society in a recent study has been estimated that 20%

recent study has been estimated that 20%

recent study has been estimated that 20% of individuals who ever high-risk

of individuals who ever high-risk

of individuals who ever high-risk infancy can account as adult for 80% of

infancy can account as adult for 80% of

infancy can account as adult for 80% of the economic burden for our society in

the economic burden for our society in

the economic burden for our society in conclusion what I told you today has a

conclusion what I told you today has a

conclusion what I told you today has a biological factor to the link between

biological factor to the link between

biological factor to the link between our physiology and behavior early in

our physiology and behavior early in

our physiology and behavior early in life and our adult life the idea I want

life and our adult life the idea I want

life and our adult life the idea I want to pass to you is that we are suited to

to pass to you is that we are suited to

to pass to you is that we are suited to get the best hour our life we can

get the best hour our life we can

get the best hour our life we can develop a proper physiology and behavior

develop a proper physiology and behavior

develop a proper physiology and behavior that maximize our interest across life

that maximize our interest across life

that maximize our interest across life but what I also told you that in the

but what I also told you that in the

but what I also told you that in the equation between an early life and adult

equation between an early life and adult

equation between an early life and adult life there is a new entry

life there is a new entry

life there is a new entry but we should take seriously in

but we should take seriously in

but we should take seriously in consideration and this is sleep and

consideration and this is sleep and

consideration and this is sleep and particularly talking about REM sleep

particularly talking about REM sleep

particularly talking about REM sleep what I also told you that there are

what I also told you that there are

what I also told you that there are specific genes that regulate all this

specific genes that regulate all this

specific genes that regulate all this mechanism and in particular I mention

mechanism and in particular I mention

mechanism and in particular I mention the imprinted genes the problem raised

the imprinted genes the problem raised

the imprinted genes the problem raised when we increase the risk for our

when we increase the risk for our

when we increase the risk for our individuals and high risk conditions

individuals and high risk conditions

individuals and high risk conditions usually occurs when the individual is

usually occurs when the individual is

usually occurs when the individual is vulnerable for example soon after birth

vulnerable for example soon after birth

vulnerable for example soon after birth when our physiology and our behavior are

when our physiology and our behavior are

when our physiology and our behavior are not fully developed at that stage we are

not fully developed at that stage we are

not fully developed at that stage we are particularly vulnerable so if something

particularly vulnerable so if something

particularly vulnerable so if something goes wrong at that stage the

goes wrong at that stage the

goes wrong at that stage the consequences are dramatic for the

consequences are dramatic for the

consequences are dramatic for the individual but also for the rest of

individual but also for the rest of

individual but also for the rest of society society however the good news is

society society however the good news is

society society however the good news is that will make great progress in

that will make great progress in

that will make great progress in understanding these risk factors we do

understanding these risk factors we do

understanding these risk factors we do constantly research in trying to

constantly research in trying to

constantly research in trying to understand how genetics and external

understand how genetics and external

understand how genetics and external factors influence our biology but also

factors influence our biology but also

factors influence our biology but also mental health so our ultimate goal as a

mental health so our ultimate goal as a

mental health so our ultimate goal as a scientist will be to provide a complete

scientist will be to provide a complete

scientist will be to provide a complete understanding of the genetics of our

understanding of the genetics of our

understanding of the genetics of our physiology and behavior and hopefully

physiology and behavior and hopefully

physiology and behavior and hopefully this will reduce dramatically the global

this will reduce dramatically the global

this will reduce dramatically the global psychological suffering of the

psychological suffering of the

psychological suffering of the population but also will reduce the

population but also will reduce the

population but also will reduce the burden for our economy thank

burden for our economy thank

burden for our economy thank [Applause]

”

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