I’m gonna ask a few I’m gonna throw it a few words or thoughts and just react to
few words or thoughts and just react to
few words or thoughts and just react to them Airbnb uber to companies who are
them Airbnb uber to companies who are
them Airbnb uber to companies who are totally you’re reinventing their
totally you’re reinventing their
totally you’re reinventing their business okay manufacturing something
business okay manufacturing something
business okay manufacturing something very complex yep
very complex yep
very complex yep judo or jiu-jitsu a way you want to
judo or jiu-jitsu a way you want to
judo or jiu-jitsu a way you want to fight if you’re smaller he’s a big guy
fight if you’re smaller he’s a big guy
fight if you’re smaller he’s a big guy inside
inside
inside Syke enough full virus who heard so many
Syke enough full virus who heard so many
Syke enough full virus who heard so many children yeah so many people know Conan
children yeah so many people know Conan
children yeah so many people know Conan O’Brien grew up across the street from
O’Brien grew up across the street from
O’Brien grew up across the street from here and it’s dad Tom O’Brien is when
here and it’s dad Tom O’Brien is when
here and it’s dad Tom O’Brien is when the top infectious disease guy so we’ll
the top infectious disease guy so we’ll
the top infectious disease guy so we’ll circle back to infectious disease
circle back to infectious disease
circle back to infectious disease Silicon Valley crazy people
Silicon Valley crazy people
Silicon Valley crazy people okay a company you know we gave an award
okay a company you know we gave an award
okay a company you know we gave an award earlier lifetime streamer award to the
earlier lifetime streamer award to the
earlier lifetime streamer award to the visit count team Microsoft has done
visit count team Microsoft has done
visit count team Microsoft has done pretty well with software what do you
pretty well with software what do you
pretty well with software what do you think of Microsoft and and what they’ve
think of Microsoft and and what they’ve
think of Microsoft and and what they’ve done with software
done with software
done with software I think they enable us to just change
I think they enable us to just change
I think they enable us to just change how we how we work how we think how we
how we how we work how we think how we
how we how we work how we think how we create blockbuster blockbuster movie
create blockbuster blockbuster movie
create blockbuster blockbuster movie blockbuster yeah blockbuster
blockbuster yeah blockbuster
blockbuster yeah blockbuster billion-dollar blockbuster what do you
billion-dollar blockbuster what do you
billion-dollar blockbuster what do you think sometimes good movies sometimes
think sometimes good movies sometimes
think sometimes good movies sometimes not so good movies yeah patience that’s
not so good movies yeah patience that’s
not so good movies yeah patience that’s why I get up in the morning for your
why I get up in the morning for your
why I get up in the morning for your patience
patience
patience unicorn when you think of the word
unicorn when you think of the word
unicorn when you think of the word unicorn it’s French anymore yeah great
unicorn it’s French anymore yeah great
unicorn it’s French anymore yeah great so you had lived in the u.s. four times
so you had lived in the u.s. four times
so you had lived in the u.s. four times this is your fourth time you grew up in
this is your fourth time you grew up in
this is your fourth time you grew up in France in 2008 to 11
France in 2008 to 11
France in 2008 to 11 you were running a company that did
you were running a company that did
you were running a company that did pretty well you had six thousand
pretty well you had six thousand
pretty well you had six thousand employees they all report to you not all
employees they all report to you not all
employees they all report to you not all the CEO of a company with six thousand
the CEO of a company with six thousand
the CEO of a company with six thousand five billion dollar company it was
five billion dollar company it was
five billion dollar company it was number one in space blood Diagnostics
number one in space blood Diagnostics
number one in space blood Diagnostics you spent two years in France and you
you spent two years in France and you
you spent two years in France and you moved here and ran it for three years
moved here and ran it for three years
moved here and ran it for three years when you were done running that you
when you were done running that you
when you were done running that you could have just bought an island and
could have just bought an island and
could have just bought an island and done nothing is that true not that
done nothing is that true not that
done nothing is that true not that that’s your inclination but is that true
that’s your inclination but is that true
that’s your inclination but is that true or false kind of true
or false kind of true
or false kind of true kinda true so you didn’t need to work
kinda true so you didn’t need to work
kinda true so you didn’t need to work another day in your life you’d helped a
another day in your life you’d helped a
another day in your life you’d helped a lot of people in the health space but
lot of people in the health space but
lot of people in the health space but you decided to jump in is that right
you decided to jump in is that right
you decided to jump in is that right yeah so in 2012 we started text weakened
yeah so in 2012 we started text weakened
yeah so in 2012 we started text weakened screen 2014 we asked you to give a talk
screen 2014 we asked you to give a talk
screen 2014 we asked you to give a talk here how what was that process like in
here how what was that process like in
here how what was that process like in terms of helping you with this little
terms of helping you with this little
terms of helping you with this little company that you’ve been leading
company that you’ve been leading
company that you’ve been leading recently so I was very helpful in two
recently so I was very helpful in two
recently so I was very helpful in two ways I think the first way was you know
ways I think the first way was you know
ways I think the first way was you know we do something that’s very science II
we do something that’s very science II
we do something that’s very science II we do messenger RNA which I guess some
we do messenger RNA which I guess some
we do messenger RNA which I guess some people in the room don’t know what it is
people in the room don’t know what it is
people in the room don’t know what it is so I’ll come back to that later do you
so I’ll come back to that later do you
so I’ll come back to that later do you will so so we just are trying to invent
will so so we just are trying to invent
will so so we just are trying to invent a new way to make medicine just totally
a new way to make medicine just totally
a new way to make medicine just totally new ways so that your body is making the
new ways so that your body is making the
new ways so that your body is making the medicine not in a factory on the other
medicine not in a factory on the other
medicine not in a factory on the other side of the planet but your body makes
side of the planet but your body makes
side of the planet but your body makes you own medicine when you’re sick so
you own medicine when you’re sick so
you own medicine when you’re sick so just totally crazy way to do it so that
just totally crazy way to do it so that
just totally crazy way to do it so that was very helpful to help me figure out
was very helpful to help me figure out
was very helpful to help me figure out how do I explain this
how do I explain this
how do I explain this this crazy concept to people who don’t
this crazy concept to people who don’t
this crazy concept to people who don’t know the biotech space the second way
know the biotech space the second way
know the biotech space the second way way was very helpful is because he was
way was very helpful is because he was
way was very helpful is because he was on a web and on tell that I had so many
on a web and on tell that I had so many
on a web and on tell that I had so many employees prospect you know coming to
employees prospect you know coming to
employees prospect you know coming to the office saying hey I’m coming from an
the office saying hey I’m coming from an
the office saying hey I’m coming from an interview I already saw a TED talk I
interview I already saw a TED talk I
interview I already saw a TED talk I think I get it same thing with suppliers
think I get it same thing with suppliers
think I get it same thing with suppliers partners so that’s really helped us find
partners so that’s really helped us find
partners so that’s really helped us find a structure to explain what we do to
a structure to explain what we do to
a structure to explain what we do to people who do not know what we do so
people who do not know what we do so
people who do not know what we do so third-party validation yes you have your
third-party validation yes you have your
third-party validation yes you have your fiber in place so those of you don’t
fiber in place so those of you don’t
fiber in place so those of you don’t know moderna some companies raise money
know moderna some companies raise money
know moderna some companies raise money they’ve successfully raised 1.9 million
they’ve successfully raised 1.9 million
they’ve successfully raised 1.9 million dollars you misspoke I misspoke 1.9
dollars you misspoke I misspoke 1.9
dollars you misspoke I misspoke 1.9 billion dollars
billion dollars
billion dollars right now yeah right now they’re
right now yeah right now they’re
right now yeah right now they’re evaluated at a five billion dollars and
evaluated at a five billion dollars and
evaluated at a five billion dollars and they are a unicorn they are the Airbnb
they are a unicorn they are the Airbnb
they are a unicorn they are the Airbnb of biotech you were looking at the Mark
of biotech you were looking at the Mark
of biotech you were looking at the Mark Zuckerberg a biotech I don’t know if he
Zuckerberg a biotech I don’t know if he
Zuckerberg a biotech I don’t know if he would claim that but many people have
would claim that but many people have
would claim that but many people have referred to him as that so again he
referred to him as that so again he
referred to him as that so again he didn’t go live in an island he said I
didn’t go live in an island he said I
didn’t go live in an island he said I want to do something remarkable and you
want to do something remarkable and you
want to do something remarkable and you an interesting path you went to business
an interesting path you went to business
an interesting path you went to business school and while all your peers went
school and while all your peers went
school and while all your peers went into the dot-com space fill’ sanderson
into the dot-com space fill’ sanderson
into the dot-com space fill’ sanderson was up here’s a guy who helped create
was up here’s a guy who helped create
was up here’s a guy who helped create Pandora he did calm space you went into
Pandora he did calm space you went into
Pandora he did calm space you went into manufacturing and what’s that a smart
manufacturing and what’s that a smart
manufacturing and what’s that a smart choice or did that kind of derail you or
choice or did that kind of derail you or
choice or did that kind of derail you or has that play out again I’ve always been
has that play out again I’ve always been
has that play out again I’ve always been in love with making medicine and I
in love with making medicine and I
in love with making medicine and I thought it was important for me to know
thought it was important for me to know
thought it was important for me to know how actually to physically make medicine
how actually to physically make medicine
how actually to physically make medicine because if you look at it all the
because if you look at it all the
because if you look at it all the pharmaceutical company all of them in
pharmaceutical company all of them in
pharmaceutical company all of them in the last 20 years all had big FDA issue
the last 20 years all had big FDA issue
the last 20 years all had big FDA issue we saw Jen’s I’m here you know a few
we saw Jen’s I’m here you know a few
we saw Jen’s I’m here you know a few miles away from here and it always put
miles away from here and it always put
miles away from here and it always put them on their knees and I was like it’s
them on their knees and I was like it’s
them on their knees and I was like it’s crazy to spend so much time in the labs
crazy to spend so much time in the labs
crazy to spend so much time in the labs making those medicines if you cannot
making those medicines if you cannot
making those medicines if you cannot find a way to make them move the right
find a way to make them move the right
find a way to make them move the right quality to get them to patients so I
quality to get them to patients so I
quality to get them to patients so I wanted to spend a bit of time learning
wanted to spend a bit of time learning
wanted to spend a bit of time learning working in a factory how to do that and
working in a factory how to do that and
working in a factory how to do that and that has been something that has helped
that has been something that has helped
that has been something that has helped me almost very good investment for you
me almost very good investment for you
me almost very good investment for you to be a black belt
to be a black belt
to be a black belt judo CEO of a biotech firm so I asked
judo CEO of a biotech firm so I asked
judo CEO of a biotech firm so I asked you about judo and jiu-jitsu so those of
you about judo and jiu-jitsu so those of
you about judo and jiu-jitsu so those of you who don’t know and you will know em
you who don’t know and you will know em
you who don’t know and you will know em RNA can you talk a little bit about you
RNA can you talk a little bit about you
RNA can you talk a little bit about you know we talked about how I see it as
know we talked about how I see it as
know we talked about how I see it as judo like like and this is a software of
judo like like and this is a software of
judo like like and this is a software of life just just talk a little bit about
life just just talk a little bit about
life just just talk a little bit about this big idea that pulled you away from
this big idea that pulled you away from
this big idea that pulled you away from running the the company who had been
running the the company who had been
running the the company who had been running to be part of this startup it’s
running to be part of this startup it’s
running to be part of this startup it’s now 500 staff in the early years he
now 500 staff in the early years he
now 500 staff in the early years he spoke here and it was helped way the
spoke here and it was helped way the
spoke here and it was helped way the talk helped bring in some of the talent
talk helped bring in some of the talent
talk helped bring in some of the talent you have now but talk about the big idea
you have now but talk about the big idea
you have now but talk about the big idea because that is an idea worth spreading
because that is an idea worth spreading
because that is an idea worth spreading and worth putting in action yes so if
and worth putting in action yes so if
and worth putting in action yes so if you look at the dogma of biology the way
you look at the dogma of biology the way
you look at the dogma of biology the way your body works is you have your DNA
your body works is you have your DNA
your body works is you have your DNA that’s basically as all the recipes for
that’s basically as all the recipes for
that’s basically as all the recipes for all the proteins
all the proteins
all the proteins in your body around 22,000 and every
in your body around 22,000 and every
in your body around 22,000 and every time you sell needs a protein like
time you sell needs a protein like
time you sell needs a protein like insulin what he does he makes a copy of
insulin what he does he makes a copy of
insulin what he does he makes a copy of that information instruction in
that information instruction in
that information instruction in something called the messenger RNA and
something called the messenger RNA and
something called the messenger RNA and that messenger RNA makes a copy from you
that messenger RNA makes a copy from you
that messenger RNA makes a copy from you DNA goes inside your cell and makes
DNA goes inside your cell and makes
DNA goes inside your cell and makes insulin protein and you cell does that a
insulin protein and you cell does that a
insulin protein and you cell does that a trillion times per day every one of your
trillion times per day every one of your
trillion times per day every one of your cells so but where since the 70s the
cells so but where since the 70s the
cells so but where since the 70s the biotech industry has made protein
biotech industry has made protein
biotech industry has made protein medicines is they took the human gene
medicines is they took the human gene
medicines is they took the human gene from your human DNA they put it in the
from your human DNA they put it in the
from your human DNA they put it in the bacteria and they made the doctor I make
bacteria and they made the doctor I make
bacteria and they made the doctor I make the protein the way we’re trying to
the protein the way we’re trying to
the protein the way we’re trying to change how we do medicines for patients
change how we do medicines for patients
change how we do medicines for patients is what trying to make directly the
is what trying to make directly the
is what trying to make directly the messenger RNA between your DNA and your
messenger RNA between your DNA and your
messenger RNA between your DNA and your protein so we make the messenger RNA and
protein so we make the messenger RNA and
protein so we make the messenger RNA and we inject the patient the messenger RNA
we inject the patient the messenger RNA
we inject the patient the messenger RNA and their body by itself makes the
and their body by itself makes the
and their body by itself makes the protein that’s gonna cure them that’s
protein that’s gonna cure them that’s
protein that’s gonna cure them that’s what we’re trying to do so like judo is
what we’re trying to do so like judo is
what we’re trying to do so like judo is putting something in your body to use
putting something in your body to use
putting something in your body to use your body to do successful things so a
your body to do successful things so a
your body to do successful things so a lot of my wife’s father my father-in-law
lot of my wife’s father my father-in-law
lot of my wife’s father my father-in-law worked at a biotech company that was
worked at a biotech company that was
worked at a biotech company that was doing very well in the 80s and 90s and
doing very well in the 80s and 90s and
doing very well in the 80s and 90s and it’s a very different time now for those
it’s a very different time now for those
it’s a very different time now for those companies and I interacted with them
companies and I interacted with them
companies and I interacted with them when I was at MIT and a lot of these
when I was at MIT and a lot of these
when I was at MIT and a lot of these companies they feel the pressure of
companies they feel the pressure of
companies they feel the pressure of trying to create these blockbuster drugs
trying to create these blockbuster drugs
trying to create these blockbuster drugs and I asked you about blockbuster movies
and I asked you about blockbuster movies
and I asked you about blockbuster movies so you’re sitting on the technology that
so you’re sitting on the technology that
so you’re sitting on the technology that kind of big impact and I know you have
kind of big impact and I know you have
kind of big impact and I know you have you have a strategy on how to have
you have a strategy on how to have
you have a strategy on how to have impact do you feel the pressure to
impact do you feel the pressure to
impact do you feel the pressure to create a blockbuster drug that can
create a blockbuster drug that can
create a blockbuster drug that can underwrite everything you’re doing like
underwrite everything you’re doing like
underwrite everything you’re doing like how do you see the blockbuster mentality
how do you see the blockbuster mentality
how do you see the blockbuster mentality playing out at your company or is it not
playing out at your company or is it not
playing out at your company or is it not yeah actually it is not we’re trying to
yeah actually it is not we’re trying to
yeah actually it is not we’re trying to do the right biology so that we can get
do the right biology so that we can get
do the right biology so that we can get the right medicine to patients the big
the right medicine to patients the big
the right medicine to patients the big problem with a pharmaceutical industry
problem with a pharmaceutical industry
problem with a pharmaceutical industry is it’s a trial-and-error business they
is it’s a trial-and-error business they
is it’s a trial-and-error business they try millions of things for one thing to
try millions of things for one thing to
try millions of things for one thing to get approved we think that a much better
get approved we think that a much better
get approved we think that a much better way to do it is to using the software of
way to do it is to using the software of
way to do it is to using the software of life using messenger RNA is to design
life using messenger RNA is to design
life using messenger RNA is to design the right protein
the right protein
the right protein so that you’re gonna be cured once and
so that you’re gonna be cured once and
so that you’re gonna be cured once and for all that’s kind of how we think
for all that’s kind of how we think
for all that’s kind of how we think about it and so we don’t believe that
about it and so we don’t believe that
about it and so we don’t believe that you need a billion dollar drug so that
you need a billion dollar drug so that
you need a billion dollar drug so that you can make a profit so that you can
you can make a profit so that you can
you can make a profit so that you can survive we think that you could have
survive we think that you could have
survive we think that you could have much smaller medicines because these
much smaller medicines because these
much smaller medicines because these eases are much more complicated and we
eases are much more complicated and we
eases are much more complicated and we think that if you can do a drug much
think that if you can do a drug much
think that if you can do a drug much faster because you use a software of
faster because you use a software of
faster because you use a software of life if your drugs can be much cheaper
life if your drugs can be much cheaper
life if your drugs can be much cheaper because you need a very little amount of
because you need a very little amount of
because you need a very little amount of messenger RNA every time we give you the
messenger RNA every time we give you the
messenger RNA every time we give you the messenger RNA medicine for one molecule
messenger RNA medicine for one molecule
messenger RNA medicine for one molecule of mRNA getting into your body your body
of mRNA getting into your body your body
of mRNA getting into your body your body is gonna make a thousand copies so it’s
is gonna make a thousand copies so it’s
is gonna make a thousand copies so it’s a thousandfold improvement so you just
a thousandfold improvement so you just
a thousandfold improvement so you just need a very little to just help your
need a very little to just help your
need a very little to just help your body to do what it needs so that you get
body to do what it needs so that you get
body to do what it needs so that you get back healthy like Jamie go help me help
back healthy like Jamie go help me help
back healthy like Jamie go help me help you yes I don’t know if you quote that
you yes I don’t know if you quote that
you yes I don’t know if you quote that you don’t I should yeah so you know I’m
you don’t I should yeah so you know I’m
you don’t I should yeah so you know I’m in the mented reality space by day we’re
in the mented reality space by day we’re
in the mented reality space by day we’re creating a headset where you see
creating a headset where you see
creating a headset where you see three-dimensional objects it’s a new
three-dimensional objects it’s a new
three-dimensional objects it’s a new tack in a new space you’re new tech and
tack in a new space you’re new tech and
tack in a new space you’re new tech and you’re trying to you know make it
you’re trying to you know make it
you’re trying to you know make it mainstream how hard is that how easy is
mainstream how hard is that how easy is
mainstream how hard is that how easy is that what keeps you up at night you’re
that what keeps you up at night you’re
that what keeps you up at night you’re onto something can have real impacts
onto something can have real impacts
onto something can have real impacts how’s it going so I mean it’s going
how’s it going so I mean it’s going
how’s it going so I mean it’s going really amazing we now have 12 drugs that
really amazing we now have 12 drugs that
really amazing we now have 12 drugs that are in development we already have 250
are in development we already have 250
are in development we already have 250 people that have been injected with all
people that have been injected with all
people that have been injected with all medicines in Europe in the US now in
medicines in Europe in the US now in
medicines in Europe in the US now in Australia hopefully next week we should
Australia hopefully next week we should
Australia hopefully next week we should very soon start with Zika vaccine in
very soon start with Zika vaccine in
very soon start with Zika vaccine in clinical trial we just filed to be FD n
clinical trial we just filed to be FD n
clinical trial we just filed to be FD n to tell you how amazing these
to tell you how amazing these
to tell you how amazing these technologies thanks to the team that
technologies thanks to the team that
technologies thanks to the team that have builded is we started working on a
have builded is we started working on a
have builded is we started working on a Zika vaccine last December at December
Zika vaccine last December at December
Zika vaccine last December at December 2015 we filed to u.s. fda a month ago to
2015 we filed to u.s. fda a month ago to
2015 we filed to u.s. fda a month ago to get the authorization to start clinical
get the authorization to start clinical
get the authorization to start clinical trial that is ten moves from having
trial that is ten moves from having
trial that is ten moves from having nothing just an idea of let’s do it the
nothing just an idea of let’s do it the
nothing just an idea of let’s do it the carboxy to being ready that process in
carboxy to being ready that process in
carboxy to being ready that process in big pharma takes five to six years
big pharma takes five to six years
big pharma takes five to six years it’s just how crazy this is and we have
it’s just how crazy this is and we have
it’s just how crazy this is and we have done 15 of those vaccines with just
done 15 of those vaccines with just
done 15 of those vaccines with just different no viruses and so things are
different no viruses and so things are
different no viruses and so things are going really well the thing I worry the
going really well the thing I worry the
going really well the thing I worry the most at night is we clearly have a true
most at night is we clearly have a true
most at night is we clearly have a true platform because the difference between
platform because the difference between
platform because the difference between the mRNA for in
the mRNA for in
the mRNA for in aleem off of a Zika vaccine it’s just
aleem off of a Zika vaccine it’s just
aleem off of a Zika vaccine it’s just the sequence over laterals like in
the sequence over laterals like in
the sequence over laterals like in software you have zeros and ones in
software you have zeros and ones in
software you have zeros and ones in messenger Arnie you have four letters
messenger Arnie you have four letters
messenger Arnie you have four letters and so the difference between those two
and so the difference between those two
and so the difference between those two products is just four letters so it
products is just four letters so it
products is just four letters so it takes a lot of time a lot of research to
takes a lot of time a lot of research to
takes a lot of time a lot of research to get the first drug to work but then the
get the first drug to work but then the
get the first drug to work but then the second the third the fourth they go very
second the third the fourth they go very
second the third the fourth they go very very fast we now make a thousand
very fast we now make a thousand
very fast we now make a thousand different messenger RNA drug every month
different messenger RNA drug every month
different messenger RNA drug every month if you will come to see us you know in
if you will come to see us you know in
if you will come to see us you know in Kendall Square we have just a huge farm
Kendall Square we have just a huge farm
Kendall Square we have just a huge farm of robots that just crank messenger RNA
of robots that just crank messenger RNA
of robots that just crank messenger RNA so you see the up side of a platform is
so you see the up side of a platform is
so you see the up side of a platform is speed scalability the thing I worry
speed scalability the thing I worry
speed scalability the thing I worry about is the downside because now that
about is the downside because now that
about is the downside because now that we know this is safe and working in
we know this is safe and working in
we know this is safe and working in human and we’re going to be publishing
human and we’re going to be publishing
human and we’re going to be publishing the clinical data early in a new year is
the clinical data early in a new year is
the clinical data early in a new year is I worry about what can we mess up
I worry about what can we mess up
I worry about what can we mess up because if you make a mistake you pick
because if you make a mistake you pick
because if you make a mistake you pick the wrong chemistry you make a
the wrong chemistry you make a
the wrong chemistry you make a manufacturing mistake all the drugs are
manufacturing mistake all the drugs are
manufacturing mistake all the drugs are wrong that’s the downside of a platform
wrong that’s the downside of a platform
wrong that’s the downside of a platform so what I spend a lot of time with a
so what I spend a lot of time with a
so what I spend a lot of time with a team now thinking about is what can go
team now thinking about is what can go
team now thinking about is what can go wrong because we can see a path to
wrong because we can see a path to
wrong because we can see a path to having dozens of drugs getting to
having dozens of drugs getting to
having dozens of drugs getting to patients so small medicine some for big
patients so small medicine some for big
patients so small medicine some for big markets we don’t really care we’re not
markets we don’t really care we’re not
markets we don’t really care we’re not solving for the size of a market were
solving for the size of a market were
solving for the size of a market were solving for medicines that only help
solving for medicines that only help
solving for medicines that only help people and the world team is really
people and the world team is really
people and the world team is really committed by that mission but the thing
committed by that mission but the thing
committed by that mission but the thing I worry a lot about is what are the
I worry a lot about is what are the
I worry a lot about is what are the things that we don’t know because it’s a
things that we don’t know because it’s a
things that we don’t know because it’s a new technology nobody has done messenger
new technology nobody has done messenger
new technology nobody has done messenger RNA drugs before so you cannot take a
RNA drugs before so you cannot take a
RNA drugs before so you cannot take a book written by MIT you know how you do
book written by MIT you know how you do
book written by MIT you know how you do a messenger RNA drug or how do you build
a messenger RNA drug or how do you build
a messenger RNA drug or how do you build a messenger RNA company we are inventing
a messenger RNA company we are inventing
a messenger RNA company we are inventing it and a bit like we saw before with a
it and a bit like we saw before with a
it and a bit like we saw before with a mountain which is we’re trying to figure
mountain which is we’re trying to figure
mountain which is we’re trying to figure ways what could go wrong every time you
ways what could go wrong every time you
ways what could go wrong every time you decide to I go right or do I go left try
decide to I go right or do I go left try
decide to I go right or do I go left try to be thoughtful about it because if you
to be thoughtful about it because if you
to be thoughtful about it because if you knew everything it’s much easier to make
knew everything it’s much easier to make
knew everything it’s much easier to make a decision but not knowing is what make
a decision but not knowing is what make
a decision but not knowing is what make it very hard for us and what makes it
it very hard for us and what makes it
it very hard for us and what makes it very hard for the team because this is a
very hard for the team because this is a
very hard for the team because this is a company that has a lot of ambiguity so
company that has a lot of ambiguity so
company that has a lot of ambiguity so it’s all about judgment so this is a
it’s all about judgment so this is a
it’s all about judgment so this is a company that requires a lot of
company that requires a lot of
company that requires a lot of collaboration because none of us
collaboration because none of us
collaboration because none of us starting with a C or none of us knows it
starting with a C or none of us knows it
starting with a C or none of us knows it all and so we have to work together as
all and so we have to work together as
all and so we have to work together as teams to listen to which
teams to listen to which
teams to listen to which and try to figure out what is a power
and try to figure out what is a power
and try to figure out what is a power forward so we don’t fall from the
forward so we don’t fall from the
forward so we don’t fall from the mountain sure and you know you just
mountain sure and you know you just
mountain sure and you know you just mentioned 12 you know most companies
mentioned 12 you know most companies
mentioned 12 you know most companies would do one or two the people who gave
would do one or two the people who gave
would do one or two the people who gave you the 1.9 billion probably didn’t
you the 1.9 billion probably didn’t
you the 1.9 billion probably didn’t think you would be you know having so
think you would be you know having so
think you would be you know having so many so many experiments going on
many so many experiments going on
many so many experiments going on concurrently but that shows that the
concurrently but that shows that the
concurrently but that shows that the technology is creating these these new
technology is creating these these new
technology is creating these these new new ways of approaching it do you think
new ways of approaching it do you think
new ways of approaching it do you think there’ll be many copycats I know iRobot
there’ll be many copycats I know iRobot
there’ll be many copycats I know iRobot you know I asked you about Silicon
you know I asked you about Silicon
you know I asked you about Silicon Valley and a lot of people go there you
Valley and a lot of people go there you
Valley and a lot of people go there you know this is sort of the Silicon Valley
know this is sort of the Silicon Valley
know this is sort of the Silicon Valley for biotech do you think there’ll be a
for biotech do you think there’ll be a
for biotech do you think there’ll be a lot of copycats of what your company’s
lot of copycats of what your company’s
lot of copycats of what your company’s doing there seventy robot companies now
doing there seventy robot companies now
doing there seventy robot companies now in Boston do you think you’re kind of
in Boston do you think you’re kind of
in Boston do you think you’re kind of changing the vector of biotech by what
changing the vector of biotech by what
changing the vector of biotech by what you’re doing yeah so what is interesting
you’re doing yeah so what is interesting
you’re doing yeah so what is interesting is because most things in biotech have
is because most things in biotech have
is because most things in biotech have not worked
not worked
not worked if you look at the last 40 years you
if you look at the last 40 years you
if you look at the last 40 years you have two types of people some that still
have two types of people some that still
have two types of people some that still think this is crazy and most probably
think this is crazy and most probably
think this is crazy and most probably will not work so can’t wait to share
will not work so can’t wait to share
will not work so can’t wait to share with them the data in the new year
with them the data in the new year
with them the data in the new year because I have seen the data and the
because I have seen the data and the
because I have seen the data and the other side is trying to emulate us so
other side is trying to emulate us so
other side is trying to emulate us so you have small companies or some big
you have small companies or some big
you have small companies or some big companies trying the thing that I think
companies trying the thing that I think
companies trying the thing that I think makes us quite unique is how fast we are
makes us quite unique is how fast we are
makes us quite unique is how fast we are learning we realized maybe a year into
learning we realized maybe a year into
learning we realized maybe a year into the company that because nobody had done
the company that because nobody had done
the company that because nobody had done messenger RNA drugs that it was going to
messenger RNA drugs that it was going to
messenger RNA drugs that it was going to be a 20-year learning cycle if you look
be a 20-year learning cycle if you look
be a 20-year learning cycle if you look at any technology mine kind of stretched
at any technology mine kind of stretched
at any technology mine kind of stretched ever it’s around 20 years that it takes
ever it’s around 20 years that it takes
ever it’s around 20 years that it takes no steam engine semiconductor mobile
no steam engine semiconductor mobile
no steam engine semiconductor mobile phone pick your favorite technology it
phone pick your favorite technology it
phone pick your favorite technology it takes 20 years for us as a society to
takes 20 years for us as a society to
takes 20 years for us as a society to kind of maximize what this technology
kind of maximize what this technology
kind of maximize what this technology can do now modern is five years old I
can do now modern is five years old I
can do now modern is five years old I still think we are still on day one we
still think we are still on day one we
still think we are still on day one we are still learning so much
are still learning so much
are still learning so much most recently Steven ruins all of our
most recently Steven ruins all of our
most recently Steven ruins all of our science it’s all the board of directors
science it’s all the board of directors
science it’s all the board of directors we have learned know in the last four
we have learned know in the last four
we have learned know in the last four most then we learned in the last four
most then we learned in the last four
most then we learned in the last four years and that is true I can learn in
years and that is true I can learn in
years and that is true I can learn in company so my last question I know your
company so my last question I know your
company so my last question I know your your mom’s here and your two daughters
your mom’s here and your two daughters
your mom’s here and your two daughters are here where do you think this goes in
are here where do you think this goes in
are here where do you think this goes in ten years we think at TEDx Beacon Street
ten years we think at TEDx Beacon Street
ten years we think at TEDx Beacon Street intergenerationally and kind of thinking
intergenerationally and kind of thinking
intergenerationally and kind of thinking about community what’s the impact ten
about community what’s the impact ten
about community what’s the impact ten years out of
years out of
years out of the great work that your team’s doing so
the great work that your team’s doing so
the great work that your team’s doing so the goal I have for the company is to
the goal I have for the company is to
the goal I have for the company is to something that has never been ever done
something that has never been ever done
something that has never been ever done is in the next ten years I want 100
is in the next ten years I want 100
is in the next ten years I want 100 medicine to go to patients and some are
medicine to go to patients and some are
medicine to go to patients and some are gonna be for very small diseases some
gonna be for very small diseases some
gonna be for very small diseases some other need for very big diseases this
other need for very big diseases this
other need for very big diseases this model doesn’t work for the big pharma
model doesn’t work for the big pharma
model doesn’t work for the big pharma correct yeah that’s a big idea and we
correct yeah that’s a big idea and we
correct yeah that’s a big idea and we really just care about getting drugs
really just care about getting drugs
really just care about getting drugs that are going to impact families help
that are going to impact families help
that are going to impact families help people that’s how we define success and
people that’s how we define success and
people that’s how we define success and we want to make sure given the breadth
we want to make sure given the breadth
we want to make sure given the breadth of a platform that we don’t try to be
of a platform that we don’t try to be
of a platform that we don’t try to be naive of to be arrogant to try to do
naive of to be arrogant to try to do
naive of to be arrogant to try to do everything ourselves we’re working with
everything ourselves we’re working with
everything ourselves we’re working with partners new AstraZeneca vertex for you
partners new AstraZeneca vertex for you
partners new AstraZeneca vertex for you know cystic fibrosis the judo jujutsu
know cystic fibrosis the judo jujutsu
know cystic fibrosis the judo jujutsu correct we’re trying to figure out some
correct we’re trying to figure out some
correct we’re trying to figure out some of the drugs that make sense for us to
of the drugs that make sense for us to
of the drugs that make sense for us to do but some drugs makes more sense for
do but some drugs makes more sense for
do but some drugs makes more sense for us to partner because those other
us to partner because those other
us to partner because those other companies are the clinical research
companies are the clinical research
companies are the clinical research regulatory capabilities for that disease
regulatory capabilities for that disease
regulatory capabilities for that disease they will take us years to build and
they will take us years to build and
they will take us years to build and we’ll always have a chance to build it
we’ll always have a chance to build it
we’ll always have a chance to build it wrong but because we care so deeply
wrong but because we care so deeply
wrong but because we care so deeply about those drugs getting to patients we
about those drugs getting to patients we
about those drugs getting to patients we are just solving for that and so if
are just solving for that and so if
are just solving for that and so if somebody else is much better fitted and
somebody else is much better fitted and
somebody else is much better fitted and this would ever drive so thank you for
this would ever drive so thank you for
this would ever drive so thank you for not buying that island and retiring I
not buying that island and retiring I
not buying that island and retiring I love your line software of life and in
love your line software of life and in
love your line software of life and in two years clear schedule we want you
two years clear schedule we want you
two years clear schedule we want you back here to give us a next update lady
back here to give us a next update lady
back here to give us a next update lady interested and gentlemen the CEO of
interested and gentlemen the CEO of
interested and gentlemen the CEO of moderna
”
Be First to Comment