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TEDx UFS 2017 – Dr. Sal Morgera: The Grandest Social Network | Sal Morgera | TEDxUSF


the grandest social network is the brain

the grandest social network is the brain it’s the end of the social network it’s

it’s the end of the social network it’s

it’s the end of the social network it’s had in its present shape and size about

had in its present shape and size about

had in its present shape and size about two million years to evolve so it’s the

two million years to evolve so it’s the

two million years to evolve so it’s the grandest and oldest social network in

grandest and oldest social network in

grandest and oldest social network in the world we’ve never thought of it that

the world we’ve never thought of it that

the world we’ve never thought of it that way well if I told you that the brain

way well if I told you that the brain

way well if I told you that the brain has a hundred billion users a single

has a hundred billion users a single

has a hundred billion users a single brain your brain has a hundred billion

brain your brain has a hundred billion

brain your brain has a hundred billion users what if I told you that the way in

users what if I told you that the way in

users what if I told you that the way in which the brain communicates internally

which the brain communicates internally

which the brain communicates internally is through a technology that we’ve

is through a technology that we’ve

is through a technology that we’ve recently discovered it’s a wireless type

recently discovered it’s a wireless type

recently discovered it’s a wireless type of technology so you have the grandest

of technology so you have the grandest

of technology so you have the grandest oldest social network utilizing what is

oldest social network utilizing what is

oldest social network utilizing what is really a cutting edge technology it’s

really a cutting edge technology it’s

really a cutting edge technology it’s quite extraordinary it’s not very

quite extraordinary it’s not very

quite extraordinary it’s not very personal to me and it’s all very

personal to me and it’s all very

personal to me and it’s all very personal to you this is my mom born in

personal to you this is my mom born in

personal to you this is my mom born in 1920 diagnosed with multiple sclerosis

1920 diagnosed with multiple sclerosis

1920 diagnosed with multiple sclerosis MS in 1958 suffered about 22 years of

MS in 1958 suffered about 22 years of

MS in 1958 suffered about 22 years of progressive decline and MS is a disease

progressive decline and MS is a disease

progressive decline and MS is a disease that affects the brain the optic nerves

that affects the brain the optic nerves

that affects the brain the optic nerves the spinal cord and it impairs the

the spinal cord and it impairs the

the spinal cord and it impairs the communication in her case principle

communication in her case principle

communication in her case principle within the brain the treatment for her

within the brain the treatment for her

within the brain the treatment for her was surgical procedures very painful

was surgical procedures very painful

was surgical procedures very painful things like spinal taps drugs of course

things like spinal taps drugs of course

things like spinal taps drugs of course with some efficacy and tremendous

with some efficacy and tremendous

with some efficacy and tremendous numbers of side effects things haven’t

numbers of side effects things haven’t

numbers of side effects things haven’t changed a lot since since those days and

changed a lot since since those days and

changed a lot since since those days and the doctors really didn’t have ability

the doctors really didn’t have ability

the doctors really didn’t have ability to manage your disease and this is true

to manage your disease and this is true

to manage your disease and this is true of many neurological dysfunctions this

of many neurological dysfunctions this

of many neurological dysfunctions this is just one other examples autism

is just one other examples autism

is just one other examples autism spectrum disorder Alzheimer’s

spectrum disorder Alzheimer’s

spectrum disorder Alzheimer’s Parkinson’s the list goes on and on of

Parkinson’s the list goes on and on of

Parkinson’s the list goes on and on of these types of neurological disorders

these types of neurological disorders

these types of neurological disorders what are you going to talk about tonight

what are you going to talk about tonight

what are you going to talk about tonight everything I have to talk about tonight

everything I have to talk about tonight

everything I have to talk about tonight is about understanding the social

is about understanding the social

is about understanding the social network of the brain listening to it

network of the brain listening to it

network of the brain listening to it talking to it and not invasively

talking to it and not invasively

talking to it and not invasively diagnosing diseases of this type and

diagnosing diseases of this type and

diagnosing diseases of this type and further therapeutically treating

further therapeutically treating

further therapeutically treating diseases of this type the keyword here

diseases of this type the keyword here

diseases of this type the keyword here is non-invasive is it possible but the

is non-invasive is it possible but the

is non-invasive is it possible but the answer is yes it is possible and in

answer is yes it is possible and in

answer is yes it is possible and in order to really understand the

order to really understand the

order to really understand the possibilities which are truly limitless

possibilities which are truly limitless

possibilities which are truly limitless we need to understand the central

we need to understand the central

we need to understand the central nervous system at its most fundamental

nervous system at its most fundamental

nervous system at its most fundamental level which are the nerve fibers and

level which are the nerve fibers and

level which are the nerve fibers and when I was referring to 100 billion

when I was referring to 100 billion

when I was referring to 100 billion users in the brain before I was

users in the brain before I was

users in the brain before I was referring to the nerve fibers in the

referring to the nerve fibers in the

referring to the nerve fibers in the brain there’s about a hundred billion

brain there’s about a hundred billion

brain there’s about a hundred billion Facebook has two billion users so we’re

Facebook has two billion users so we’re

Facebook has two billion users so we’re really talking about a big social

really talking about a big social

really talking about a big social network within our own brain it’s a

network within our own brain it’s a

network within our own brain it’s a picture it’s an electron micrograph of

picture it’s an electron micrograph of

picture it’s an electron micrograph of the nerve fibers in a certain portion of

the nerve fibers in a certain portion of

the nerve fibers in a certain portion of the brain each and every one of them

the brain each and every one of them

the brain each and every one of them along its length carries an electrical

along its length carries an electrical

along its length carries an electrical impulse and some of you know we call

impulse and some of you know we call

impulse and some of you know we call this an action potential and this is the

this an action potential and this is the

this an action potential and this is the way the brain communicates to a great

way the brain communicates to a great

way the brain communicates to a great extent within itself and

extent within itself and

extent within itself and and the central nervous system

and the central nervous system

and the central nervous system throughout our body each one of these is

throughout our body each one of these is

throughout our body each one of these is very tiny they’re extraordinary each one

very tiny they’re extraordinary each one

very tiny they’re extraordinary each one of these is in diameter tinier than a

of these is in diameter tinier than a

of these is in diameter tinier than a human hair and there’s a hundred billion

human hair and there’s a hundred billion

human hair and there’s a hundred billion of there in there we’ve made two

of there in there we’ve made two

of there in there we’ve made two discoveries and these discoveries are

discoveries and these discoveries are

discoveries and these discoveries are really game changers in the

really game changers in the

really game changers in the understanding of the human brain and

understanding of the human brain and

understanding of the human brain and generally the central nervous system

generally the central nervous system

generally the central nervous system these nerve fibers don’t just carry

these nerve fibers don’t just carry

these nerve fibers don’t just carry impulses along their length but like

impulses along their length but like

impulses along their length but like neighbors packed in a dense neighborhood

neighbors packed in a dense neighborhood

neighbors packed in a dense neighborhood they talk to each other they communicate

they talk to each other they communicate

they talk to each other they communicate with each other they compete and they

with each other they compete and they

with each other they compete and they collaborate with each other they do

collaborate with each other they do

collaborate with each other they do everything that you would expect users

everything that you would expect users

everything that you would expect users and a Facebook social network to do so

and a Facebook social network to do so

and a Facebook social network to do so you have this interaction we call it

you have this interaction we call it

you have this interaction we call it cross talk between the fibers creates a

cross talk between the fibers creates a

cross talk between the fibers creates a very sophisticated Network truly

very sophisticated Network truly

very sophisticated Network truly sophisticated in addition to that the

sophisticated in addition to that the

sophisticated in addition to that the technology they use yes I can call it

technology they use yes I can call it

technology they use yes I can call it technology that they use to communicate

technology that they use to communicate

technology that they use to communicate with each other is very similar to Apple

with each other is very similar to Apple

with each other is very similar to Apple pay and Google roll it you never thought

pay and Google roll it you never thought

pay and Google roll it you never thought I’d say that but that’s that’s exactly

I’d say that but that’s that’s exactly

I’d say that but that’s that’s exactly true it’s called near field

true it’s called near field

true it’s called near field communications and you can probably not

communications and you can probably not

communications and you can probably not a good time to do it but you can take

a good time to do it but you can take

a good time to do it but you can take your cell phone out take a look on the

your cell phone out take a look on the

your cell phone out take a look on the back most of you know this and some of

back most of you know this and some of

back most of you know this and some of your phones will be enabled for

your phones will be enabled for

your phones will be enabled for contactless payment or near field

contactless payment or near field

contactless payment or near field communication similar sort of technology

communication similar sort of technology

communication similar sort of technology so once we understand these these these

so once we understand these these these

so once we understand these these these two discoveries the world opens up

two discoveries the world opens up

two discoveries the world opens up possibilities really open up because if

possibilities really open up because if

possibilities really open up because if we’re going to listen to the brain we’re

we’re going to listen to the brain we’re

we’re going to listen to the brain we’re going to be listening to near field

going to be listening to near field

going to be listening to near field communication signals like wireless

communication signals like wireless

communication signals like wireless signals and these are going to change

signals and these are going to change

signals and these are going to change with time we need to understand that as

with time we need to understand that as

with time we need to understand that as the person gets altered the signals

the person gets altered the signals

the person gets altered the signals change as a person suffers a

change as a person suffers a

change as a person suffers a neurological dysfunction

neurological dysfunction

neurological dysfunction the signals change as they go through

the signals change as they go through

the signals change as they go through the progressive stages and that’s in

the progressive stages and that’s in

the progressive stages and that’s in some ways an excellent diagnostic tool

some ways an excellent diagnostic tool

some ways an excellent diagnostic tool because we listen to those signals we

because we listen to those signals we

because we listen to those signals we sense those changes and we diagnose a

sense those changes and we diagnose a

sense those changes and we diagnose a patient non-invasively now of course we

patient non-invasively now of course we

patient non-invasively now of course we need a lot to do this I mean I might

need a lot to do this I mean I might

need a lot to do this I mean I might make it sound a little simple but in

make it sound a little simple but in

make it sound a little simple but in order to sense these signals we need

order to sense these signals we need

order to sense these signals we need very sensitive receivers we use

very sensitive receivers we use

very sensitive receivers we use extraordinary antennas we need to push

extraordinary antennas we need to push

extraordinary antennas we need to push technology which is what we’ve been

technology which is what we’ve been

technology which is what we’ve been doing in a variety of ways in addition

doing in a variety of ways in addition

doing in a variety of ways in addition to that we need to know how the language

to that we need to know how the language

to that we need to know how the language of the brain expresses itself and we’ve

of the brain expresses itself and we’ve

of the brain expresses itself and we’ve taught it spent thousands of hours

taught it spent thousands of hours

taught it spent thousands of hours talking to individuals with neurological

talking to individuals with neurological

talking to individuals with neurological dysfunctions and matching their clinical

dysfunctions and matching their clinical

dysfunctions and matching their clinical studies against what they really tell us

studies against what they really tell us

studies against what they really tell us against our own observations an

against our own observations an

against our own observations an individual with Alzheimer’s will present

individual with Alzheimer’s will present

individual with Alzheimer’s will present those symptoms in a wide variety of ways

those symptoms in a wide variety of ways

those symptoms in a wide variety of ways not just one way so we’ve developed

not just one way so we’ve developed

not just one way so we’ve developed software in an expert system kind of

software in an expert system kind of

software in an expert system kind of setting which captures all of that

setting which captures all of that

setting which captures all of that information and utilize it along with

information and utilize it along with

information and utilize it along with are very sensitive hardware so what I

are very sensitive hardware so what I

are very sensitive hardware so what I want you to do is come into the lab and

want you to do is come into the lab and

want you to do is come into the lab and take a look at a few examples and the

take a look at a few examples and the

take a look at a few examples and the two examples I have for you this evening

two examples I have for you this evening

two examples I have for you this evening one is autism spectrum disorder and the

one is autism spectrum disorder and the

one is autism spectrum disorder and the other is Alzheimer’s

other is Alzheimer’s

other is Alzheimer’s the first is autism and I’ll show it to

the first is autism and I’ll show it to

the first is autism and I’ll show it to you in two different ways because as

you in two different ways because as

you in two different ways because as humans we like to see things we like to

humans we like to see things we like to

humans we like to see things we like to hear things and sometimes that’s

hear things and sometimes that’s

hear things and sometimes that’s difficult with the brain so in order to

difficult with the brain so in order to

difficult with the brain so in order to see things we need an imaging system

see things we need an imaging system

see things we need an imaging system that takes a snapshot of the activity in

that takes a snapshot of the activity in

that takes a snapshot of the activity in the brain the activity of those nerve

the brain the activity of those nerve

the brain the activity of those nerve fibers and with autism it’s all about

fibers and with autism it’s all about

fibers and with autism it’s all about the balance between excitation and

the balance between excitation and

the balance between excitation and inhibition

inhibition

inhibition in populations of nerve fibers if there

in populations of nerve fibers if there

in populations of nerve fibers if there is a balance the individual does not

is a balance the individual does not

is a balance the individual does not present with autistic spectrum disorder

present with autistic spectrum disorder

present with autistic spectrum disorder symptoms now this picture shows us it

symptoms now this picture shows us it

symptoms now this picture shows us it looks like a truth forest where the

looks like a truth forest where the

looks like a truth forest where the trees are evenly spread across the

trees are evenly spread across the

trees are evenly spread across the landscape it’s an individual that does

landscape it’s an individual that does

landscape it’s an individual that does not present as an autistic individual so

not present as an autistic individual so

not present as an autistic individual so that we have a balance between

that we have a balance between

that we have a balance between excitation and inhibition and there’s a

excitation and inhibition and there’s a

excitation and inhibition and there’s a sound associated with this well there

sound associated with this well there

sound associated with this well there should be a sound associated with this

which is it’s say it’s a rumbling sound

which is it’s say it’s a rumbling sound but it’s a constant sound now this is an

but it’s a constant sound now this is an

but it’s a constant sound now this is an individual that presents with artists

individual that presents with artists

individual that presents with artists autistic symptoms and the serious

autistic symptoms and the serious

autistic symptoms and the serious symptoms it’s like that forest got

symptoms it’s like that forest got

symptoms it’s like that forest got plowed through and there’s a very great

plowed through and there’s a very great

plowed through and there’s a very great imbalance between excitation and

imbalance between excitation and

imbalance between excitation and inhibition so this individual sees

inhibition so this individual sees

inhibition so this individual sees colors very brightly butch brightly that

colors very brightly butch brightly that

colors very brightly butch brightly that a normal individual would see this

a normal individual would see this

a normal individual would see this individual here sounds there are

individual here sounds there are

individual here sounds there are sometimes excruciating and there’s a a

sometimes excruciating and there’s a a

sometimes excruciating and there’s a a sound that goes along with this type of

sound that goes along with this type of

sound that goes along with this type of behavior they’re the first that have

behavior they’re the first that have

behavior they’re the first that have heard these this is such a diverse

heard these this is such a diverse

heard these this is such a diverse audience really that I’ve never

audience really that I’ve never

audience really that I’ve never presented before such a wonderful group

presented before such a wonderful group

presented before such a wonderful group to actually hear these things it’s

to actually hear these things it’s

to actually hear these things it’s choppy it’s higher in frequency now

choppy it’s higher in frequency now

choppy it’s higher in frequency now what’s going on associated with these

what’s going on associated with these

what’s going on associated with these types of dysfunction the near field

types of dysfunction the near field

types of dysfunction the near field communication waves in the brain have

communication waves in the brain have

communication waves in the brain have different characteristics we call it

different characteristics we call it

different characteristics we call it different signatures and now most of

different signatures and now most of

different signatures and now most of those are very low frequency they’re

those are very low frequency they’re

those are very low frequency they’re below our threshold of hearing so in

below our threshold of hearing so in

below our threshold of hearing so in order for you to hear them I’ve had to

order for you to hear them I’ve had to

order for you to hear them I’ve had to faithfully raise them up so you could

faithfully raise them up so you could

faithfully raise them up so you could hear them and hear those differences

hear them and hear those differences

hear them and hear those differences now those differences can be used

now those differences can be used

now those differences can be used tonight of the differences and the

tonight of the differences and the

tonight of the differences and the images can be used to non-invasively

images can be used to non-invasively

images can be used to non-invasively diagnosed individuals now the next

diagnosed individuals now the next

diagnosed individuals now the next example is a little more complicated we

example is a little more complicated we

example is a little more complicated we have a brain and we have electric field

have a brain and we have electric field

have a brain and we have electric field outside the brain and first what we’re

outside the brain and first what we’re

outside the brain and first what we’re doing is listening with sensitive

doing is listening with sensitive

doing is listening with sensitive receivers to the waves in the brain that

receivers to the waves in the brain that

receivers to the waves in the brain that are associated with memory consolidation

are associated with memory consolidation

are associated with memory consolidation so the problem is one of Alzheimer’s

so the problem is one of Alzheimer’s

so the problem is one of Alzheimer’s certain times of the day in certain

certain times of the day in certain

certain times of the day in certain areas of the brain the brain waves

areas of the brain the brain waves

areas of the brain the brain waves become what we call coherent in other

become what we call coherent in other

become what we call coherent in other words they change from being rather

words they change from being rather

words they change from being rather noisy to a single frequency wave and

noisy to a single frequency wave and

noisy to a single frequency wave and when that single frequency wave occurs

when that single frequency wave occurs

when that single frequency wave occurs the brain is performing an efficient

the brain is performing an efficient

the brain is performing an efficient memory consolidation process and the

memory consolidation process and the

memory consolidation process and the individual does not present with

individual does not present with

individual does not present with Alzheimer’s when the brain remains noisy

Alzheimer’s when the brain remains noisy

Alzheimer’s when the brain remains noisy it’s the opposite the consolidation

it’s the opposite the consolidation

it’s the opposite the consolidation process is inefficient and the

process is inefficient and the

process is inefficient and the individual does not remember their wives

individual does not remember their wives

individual does not remember their wives their sons their daughters so what we’ll

their sons their daughters so what we’ll

their sons their daughters so what we’ll hear here is first the noisy signal of

hear here is first the noisy signal of

hear here is first the noisy signal of the brain and then as we apply the

the brain and then as we apply the

the brain and then as we apply the electric field very low-level electric

electric field very low-level electric

electric field very low-level electric field it trains the brain to a coherent

field it trains the brain to a coherent

field it trains the brain to a coherent state and it’s what we call a positive

state and it’s what we call a positive

state and it’s what we call a positive feedback kind of activity and starting

feedback kind of activity and starting

feedback kind of activity and starting up noisy actually build and it because

up noisy actually build and it because

up noisy actually build and it because you hear

and this is what it looks like

and this is what it looks like graphically time is in the front time

graphically time is in the front time

graphically time is in the front time goes back and if you move up the yellow

goes back and if you move up the yellow

goes back and if you move up the yellow shock then what you’re seeing really is

shock then what you’re seeing really is

shock then what you’re seeing really is a consolidation of waves in the brain a

a consolidation of waves in the brain a

a consolidation of waves in the brain a noisy state and with the electric field

noisy state and with the electric field

noisy state and with the electric field becoming much more coherent and

becoming much more coherent and

becoming much more coherent and increasing so it’s what you’ve just

increasing so it’s what you’ve just

increasing so it’s what you’ve just witnessed really is the diagnosis of an

witnessed really is the diagnosis of an

witnessed really is the diagnosis of an extraordinarily complex disease and one

extraordinarily complex disease and one

extraordinarily complex disease and one type of therapeutic treatment all

type of therapeutic treatment all

type of therapeutic treatment all non-invasive because we’re learning how

non-invasive because we’re learning how

non-invasive because we’re learning how to listen to the brain not here the

to listen to the brain not here the

to listen to the brain not here the brain but really listen to it and it’s

brain but really listen to it and it’s

brain but really listen to it and it’s dynamic language and train it if

dynamic language and train it if

dynamic language and train it if necessary these are game changers I

necessary these are game changers I

necessary these are game changers I believe this is a paradigm shift you

believe this is a paradigm shift you

believe this is a paradigm shift you know the medical profession many times

know the medical profession many times

know the medical profession many times will move toward drugs we’ve seen all

will move toward drugs we’ve seen all

will move toward drugs we’ve seen all the commercials the drugs do this they

the commercials the drugs do this they

the commercials the drugs do this they could cause this and it’s just beyond

could cause this and it’s just beyond

could cause this and it’s just beyond belief that it hasn’t changed since my

belief that it hasn’t changed since my

belief that it hasn’t changed since my mom was afflicted with multiple

mom was afflicted with multiple

mom was afflicted with multiple sclerosis

sclerosis

sclerosis and of course as I’ve grown older and

and of course as I’ve grown older and

and of course as I’ve grown older and engaged more with colleagues and a

engaged more with colleagues and a

engaged more with colleagues and a community I realized that to the left

community I realized that to the left

community I realized that to the left and to the right of me many times I see

and to the right of me many times I see

and to the right of me many times I see the millions of individuals in this

the millions of individuals in this

the millions of individuals in this world that are afflicted with

world that are afflicted with

world that are afflicted with neurological dysfunction or mental

neurological dysfunction or mental

neurological dysfunction or mental disorders and if you can do something

disorders and if you can do something

disorders and if you can do something about it it’s important to 1958 actually

about it it’s important to 1958 actually

about it it’s important to 1958 actually 1960 and the doctors told my mom have

1960 and the doctors told my mom have

1960 and the doctors told my mom have another baby because they thought that

another baby because they thought that

another baby because they thought that the the hormonal changes would help

the the hormonal changes would help

the the hormonal changes would help manage the disease I have a brother he’s

manage the disease I have a brother he’s

manage the disease I have a brother he’s a great doctor I wonder why you know

a great doctor I wonder why you know

a great doctor I wonder why you know he’s a great doctor and it didn’t help

he’s a great doctor and it didn’t help

he’s a great doctor and it didn’t help it didn’t help my mom

it didn’t help my mom

it didn’t help my mom maybe joy in her life of course bathe in

maybe joy in her life of course bathe in

maybe joy in her life of course bathe in warm water now we know that’s exactly

warm water now we know that’s exactly

warm water now we know that’s exactly the wrong thing to do and of course

the wrong thing to do and of course

the wrong thing to do and of course drugs and their side effects we can all

drugs and their side effects we can all

drugs and their side effects we can all make a difference and I think the near

make a difference and I think the near

make a difference and I think the near future holds a non-invasive diagnostic

future holds a non-invasive diagnostic

future holds a non-invasive diagnostic diagnosis diagnosis and therapeutic

diagnosis diagnosis and therapeutic

diagnosis diagnosis and therapeutic treatment of many of those things that

treatment of many of those things that

treatment of many of those things that we know do exist

we know do exist

we know do exist and every one of you probably know

and every one of you probably know

and every one of you probably know someone and I want you to take heart

someone and I want you to take heart

someone and I want you to take heart because in the near future things will

because in the near future things will

because in the near future things will improve greatly in the distant future I

improve greatly in the distant future I

improve greatly in the distant future I only leave you to imagine because the

only leave you to imagine because the

only leave you to imagine because the avenues and the opportunities I think

avenues and the opportunities I think

avenues and the opportunities I think are truly limitless

”

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