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Restoring sight to the blind | John Pezaris | TEDxUniversityofPiraeus


who here is alive okay this is an easy

who here is alive okay this is an easy question everybody should be raising

question everybody should be raising

question everybody should be raising your hand or just about everybody here

your hand or just about everybody here

your hand or just about everybody here okay thank you hands down

okay thank you hands down

okay thank you hands down who here is blind that might be one or

who here is blind that might be one or

who here is blind that might be one or two of you and for you I apologize that

two of you and for you I apologize that

two of you and for you I apologize that they’re going to be parts of this

they’re going to be parts of this

they’re going to be parts of this presentation which will not be

presentation which will not be

presentation which will not be accessible but I’ll be narrating through

accessible but I’ll be narrating through

accessible but I’ll be narrating through them so that you can understand what’s

them so that you can understand what’s

them so that you can understand what’s going on now who here knows someone who

going on now who here knows someone who

going on now who here knows someone who is blind or is losing their sight about

is blind or is losing their sight about

is blind or is losing their sight about one-third of you should had you have

one-third of you should had you have

one-third of you should had you have your hands up because about one-third of

your hands up because about one-third of

your hands up because about one-third of you in fact know someone who is blind or

you in fact know someone who is blind or

you in fact know someone who is blind or who is losing their sight whether

who is losing their sight whether

who is losing their sight whether they’ve told you that or not ask your

they’ve told you that or not ask your

they’ve told you that or not ask your parents ask your grandparents talk to

parents ask your grandparents talk to

parents ask your grandparents talk to them blindness is widespread it affects

them blindness is widespread it affects

them blindness is widespread it affects millions of people worldwide the exact

millions of people worldwide the exact

millions of people worldwide the exact number of millions depends on exactly

number of millions depends on exactly

number of millions depends on exactly how you define blindness for the

how you define blindness for the

how you define blindness for the purposes of this talk blindness will

purposes of this talk blindness will

purposes of this talk blindness will mean that you can’t walk without risking

mean that you can’t walk without risking

mean that you can’t walk without risking hitting something or someone you can’t

hitting something or someone you can’t

hitting something or someone you can’t see the food on a plate in front of you

see the food on a plate in front of you

see the food on a plate in front of you you can’t tell the color of your

you can’t tell the color of your

you can’t tell the color of your clothing or if your shoe has come untied

clothing or if your shoe has come untied

clothing or if your shoe has come untied you if your child or your grandchild

you if your child or your grandchild

you if your child or your grandchild hands you a piece of paper you can’t

hands you a piece of paper you can’t

hands you a piece of paper you can’t tell what the drawing is that they have

tell what the drawing is that they have

tell what the drawing is that they have made for you

made for you

made for you blindness is a devastating condition

blindness is a devastating condition

blindness is a devastating condition that can leave individuals isolated in

that can leave individuals isolated in

that can leave individuals isolated in withdrawn it has staggering effects

withdrawn it has staggering effects

withdrawn it has staggering effects economically in the United States where

economically in the United States where

economically in the United States where we currently have almost full employment

we currently have almost full employment

we currently have almost full employment in the general population in the blind

in the general population in the blind

in the general population in the blind population unemployment runs at about

population unemployment runs at about

population unemployment runs at about 75% blindness has significant burdens on

75% blindness has significant burdens on

75% blindness has significant burdens on the family both in terms of medical

the family both in terms of medical

the family both in terms of medical costs as well as everyday care costs the

costs as well as everyday care costs the

costs as well as everyday care costs the total cost of blindness to society in

total cost of blindness to society in

total cost of blindness to society in the United States including things like

the United States including things like

the United States including things like lost wages is three billion dollar

lost wages is three billion dollar

lost wages is three billion dollar a year interestingly most of the causes

a year interestingly most of the causes

a year interestingly most of the causes of blindness are diseases of the eyes

of blindness are diseases of the eyes

of blindness are diseases of the eyes I’m an engineer who’s become a

I’m an engineer who’s become a

I’m an engineer who’s become a neuroscientist because of a passion for

neuroscientist because of a passion for

neuroscientist because of a passion for vision and I find that very interesting

vision and I find that very interesting

vision and I find that very interesting it’s the sensors that have gone bad

it’s the sensors that have gone bad

it’s the sensors that have gone bad maybe we can fix that the most common

maybe we can fix that the most common

maybe we can fix that the most common causes of blindness in fact are glaucoma

causes of blindness in fact are glaucoma

causes of blindness in fact are glaucoma macular degeneration retinitis

macular degeneration retinitis

macular degeneration retinitis pigmentosa and these three are the

pigmentosa and these three are the

pigmentosa and these three are the biggest there are many other diseases

biggest there are many other diseases

biggest there are many other diseases including some forms of cancer but these

including some forms of cancer but these

including some forms of cancer but these are the biggest a fourth cause of

are the biggest a fourth cause of

are the biggest a fourth cause of blindness although not nearly as common

blindness although not nearly as common

blindness although not nearly as common is trauma specifically blast trauma that

is trauma specifically blast trauma that

is trauma specifically blast trauma that we find in modern warfare we find it in

we find in modern warfare we find it in

we find in modern warfare we find it in both the civilian and of the soldier in

both the civilian and of the soldier in

both the civilian and of the soldier in areas where there has been war and

areas where there has been war and

areas where there has been war and landmine fields have been left behind

landmine fields have been left behind

landmine fields have been left behind trauma Rises in frequency and becomes a

trauma Rises in frequency and becomes a

trauma Rises in frequency and becomes a leading cause of blindness among

leading cause of blindness among

leading cause of blindness among children and the developing world

children and the developing world

children and the developing world this story is slightly different and we

this story is slightly different and we

this story is slightly different and we have infection and cataract as the most

have infection and cataract as the most

have infection and cataract as the most frequent causes of blindness but those

frequent causes of blindness but those

frequent causes of blindness but those have solutions we know how to treat

have solutions we know how to treat

have solutions we know how to treat those so we won’t be talking about

those so we won’t be talking about

those so we won’t be talking about treating those individuals

treating those individuals

treating those individuals similarly for congenital blindness the

similarly for congenital blindness the

similarly for congenital blindness the brain is left without the normal

brain is left without the normal

brain is left without the normal experience of visual sight and so it

experience of visual sight and so it

experience of visual sight and so it doesn’t develop the way it normally

doesn’t develop the way it normally

doesn’t develop the way it normally would and so no one in the field is

would and so no one in the field is

would and so no one in the field is talking about treating those individuals

talking about treating those individuals

talking about treating those individuals not yet so what’s the solution

not yet so what’s the solution

not yet so what’s the solution we know the Oh in the eyes are no longer

we know the Oh in the eyes are no longer

we know the Oh in the eyes are no longer sensitive to light as neuroscientists

sensitive to light as neuroscientists

sensitive to light as neuroscientists we’ve discovered that the rest of the

we’ve discovered that the rest of the

we’ve discovered that the rest of the brain is okay and as engineers we know

brain is okay and as engineers we know

brain is okay and as engineers we know how to build cameras to capture moving

how to build cameras to capture moving

how to build cameras to capture moving images and so we can just plug that

images and so we can just plug that

images and so we can just plug that information directly into the brain and

information directly into the brain and

information directly into the brain and vision Steve Austin

vision Steve Austin

vision Steve Austin Geordi LaForge Neil we’re familiar with

Geordi LaForge Neil we’re familiar with

Geordi LaForge Neil we’re familiar with the idea from popular entertainment

the idea from popular entertainment

the idea from popular entertainment because of the technological simplicity

because of the technological simplicity

because of the technological simplicity it appears to have the basic idea looks

it appears to have the basic idea looks

it appears to have the basic idea looks like this we put a small camera like the

like this we put a small camera like the

like this we put a small camera like the one in your mobile phone into a set of

one in your mobile phone into a set of

one in your mobile phone into a set of goggles and send the video stream from

goggles and send the video stream from

goggles and send the video stream from that wirelessly to electrodes that we’ve

that wirelessly to electrodes that we’ve

that wirelessly to electrodes that we’ve implanted in the brain and that provides

implanted in the brain and that provides

implanted in the brain and that provides restoration of function or artificial

restoration of function or artificial

restoration of function or artificial sight as we call them we know how to

sight as we call them we know how to

sight as we call them we know how to build tiny cameras we know how to build

build tiny cameras we know how to build

build tiny cameras we know how to build small computers we know how to build

small computers we know how to build

small computers we know how to build wireless links and we even know how to

wireless links and we even know how to

wireless links and we even know how to build brain electrodes on both a

build brain electrodes on both a

build brain electrodes on both a scientist and an engineer so it should

scientist and an engineer so it should

scientist and an engineer so it should just work it sounds very simple but

just work it sounds very simple but

just work it sounds very simple but that’s the idea the hard part is in

that’s the idea the hard part is in

that’s the idea the hard part is in translating the camera images into the

translating the camera images into the

translating the camera images into the language of the brain the neural code

language of the brain the neural code

language of the brain the neural code and delivering that translation in a

and delivering that translation in a

and delivering that translation in a safe way to the right parts of the brain

safe way to the right parts of the brain

safe way to the right parts of the brain so that it can be used to reconstruct

so that it can be used to reconstruct

so that it can be used to reconstruct images the importance is in the details

images the importance is in the details

images the importance is in the details and in the details we find challenges in

and in the details we find challenges in

and in the details we find challenges in technology in biomedical engineering and

technology in biomedical engineering and

technology in biomedical engineering and in science most of you are familiar with

in science most of you are familiar with

in science most of you are familiar with technology but perhaps not so familiar

technology but perhaps not so familiar

technology but perhaps not so familiar with neuroscience so here’s a very quick

with neuroscience so here’s a very quick

with neuroscience so here’s a very quick introduction this drawing is the

introduction this drawing is the

introduction this drawing is the underside view of a human brain where

underside view of a human brain where

underside view of a human brain where I’ve labeled the different stages of

I’ve labeled the different stages of

I’ve labeled the different stages of what’s called the early visual pathway

what’s called the early visual pathway

what’s called the early visual pathway it’s called the early visual pathway

it’s called the early visual pathway

it’s called the early visual pathway because it’s the first few stages in a

because it’s the first few stages in a

because it’s the first few stages in a very long chain of visual processing

very long chain of visual processing

very long chain of visual processing light enters the eyes and falls on the

light enters the eyes and falls on the

light enters the eyes and falls on the retina where it turns into neural

retina where it turns into neural

retina where it turns into neural activity most of the diseases that I

activity most of the diseases that I

activity most of the diseases that I mentioned that cause blindness interfere

mentioned that cause blindness interfere

mentioned that cause blindness interfere with that process and leave the eyes no

with that process and leave the eyes no

with that process and leave the eyes no longer sensitive to light when the eyes

longer sensitive to light when the eyes

longer sensitive to light when the eyes are working normally however the signals

are working normally however the signals

are working normally however the signals fall through the optic nerve to the

fall through the optic nerve to the

fall through the optic nerve to the lateral geniculate nucleus or LGN as

lateral geniculate nucleus or LGN as

lateral geniculate nucleus or LGN as I’ve shown here then through the optic

I’ve shown here then through the optic

I’ve shown here then through the optic radiation to the primary visual cortex

radiation to the primary visual cortex

radiation to the primary visual cortex at the back of the head that’s where

at the back of the head that’s where

at the back of the head that’s where conscious vision begins

conscious vision begins

conscious vision begins from there it moves on to other parts of

from there it moves on to other parts of

from there it moves on to other parts of the brain where things happen like

the brain where things happen like

the brain where things happen like recognizing people places or things

recognizing people places or things

recognizing people places or things about 40% of the brain is devoted to

about 40% of the brain is devoted to

about 40% of the brain is devoted to vision to restore sight to the blind

vision to restore sight to the blind

vision to restore sight to the blind where the eyes are no longer functioning

where the eyes are no longer functioning

where the eyes are no longer functioning we can think about putting signals from

we can think about putting signals from

we can think about putting signals from electronic camera into any of these

electronic camera into any of these

electronic camera into any of these stages of the early visual system each

stages of the early visual system each

stages of the early visual system each stages each stage uses a slightly

stages each stage uses a slightly

stages each stage uses a slightly different encoding a slightly different

different encoding a slightly different

different encoding a slightly different neural language but we understand most

neural language but we understand most

neural language but we understand most of those thanks to decades of work we

of those thanks to decades of work we

of those thanks to decades of work we are in fact standing on the shoulders of

are in fact standing on the shoulders of

are in fact standing on the shoulders of giants

giants

giants there is evidence going back a hundred

there is evidence going back a hundred

there is evidence going back a hundred years that we can generate visual

years that we can generate visual

years that we can generate visual experience by stimulating the brain

experience by stimulating the brain

experience by stimulating the brain different parts of the brain perhaps the

different parts of the brain perhaps the

different parts of the brain perhaps the first important attempt at a visual

first important attempt at a visual

first important attempt at a visual prosthesis was by Brindley and Lewin at

prosthesis was by Brindley and Lewin at

prosthesis was by Brindley and Lewin at the University of Cambridge in the late

the University of Cambridge in the late

the University of Cambridge in the late 1960s they put 80 electrodes on the

1960s they put 80 electrodes on the

1960s they put 80 electrodes on the primary visual cortex surface in a

primary visual cortex surface in a

primary visual cortex surface in a brilliant bit of bioengineering that was

brilliant bit of bioengineering that was

brilliant bit of bioengineering that was well ahead of its time they were able to

well ahead of its time they were able to

well ahead of its time they were able to use these electrodes to generate little

use these electrodes to generate little

use these electrodes to generate little points of light little stars or small

points of light little stars or small

points of light little stars or small fuzzy circles and we call those

fuzzy circles and we call those

fuzzy circles and we call those phosphenes phosphenes our visual

phosphenes phosphenes our visual

phosphenes phosphenes our visual experiences that are created without

experiences that are created without

experiences that are created without visual input you see them for example

visual input you see them for example

visual input you see them for example when you go to sleep at night or before

when you go to sleep at night or before

when you go to sleep at night or before you go to sleep at night when you close

you go to sleep at night when you close

you go to sleep at night when you close your eyes those purple and greenish

your eyes those purple and greenish

your eyes those purple and greenish waves you see them if you hit your head

waves you see them if you hit your head

waves you see them if you hit your head too hard we call that seeing stars each

too hard we call that seeing stars each

too hard we call that seeing stars each of those stars is a phosphine will you

of those stars is a phosphine will you

of those stars is a phosphine will you see them when a cosmic ray hits your

see them when a cosmic ray hits your

see them when a cosmic ray hits your retina like for astronauts who

retina like for astronauts who

retina like for astronauts who frequently report phosphenes so we think

frequently report phosphenes so we think

frequently report phosphenes so we think we can create small phosphines the

we can create small phosphines the

we can create small phosphines the pixels of artificial sight by applying

pixels of artificial sight by applying

pixels of artificial sight by applying electrical stimulation to any part of

electrical stimulation to any part of

electrical stimulation to any part of the early visual system worldwide there

the early visual system worldwide there

the early visual system worldwide there are about two dozen groups working on

are about two dozen groups working on

are about two dozen groups working on creating a visual prosthesis and each of

creating a visual prosthesis and each of

creating a visual prosthesis and each of them take a slightly different approach

them take a slightly different approach

them take a slightly different approach many of them put electrodes in the eye

many of them put electrodes in the eye

many of them put electrodes in the eye some like my group put them in the

some like my group put them in the

some like my group put them in the and some put them in the primary visual

and some put them in the primary visual

and some put them in the primary visual cortex but they all more or less follow

cortex but they all more or less follow

cortex but they all more or less follow the same idea they use a man-made an

the same idea they use a man-made an

the same idea they use a man-made an imaging system to apply patterns of

imaging system to apply patterns of

imaging system to apply patterns of electrical stimulation to restore sight

electrical stimulation to restore sight

electrical stimulation to restore sight they also more or less all face the same

they also more or less all face the same

they also more or less all face the same big problem the visual system is amazing

big problem the visual system is amazing

big problem the visual system is amazing and amazingly experience detailed

and amazingly experience detailed

and amazingly experience detailed experience that it gives you no one is

experience that it gives you no one is

experience that it gives you no one is talking about restoring normal vision no

talking about restoring normal vision no

talking about restoring normal vision no one all of these groups are creating

one all of these groups are creating

one all of these groups are creating devices that provide only very crude

devices that provide only very crude

devices that provide only very crude artificial sight better than blindness

artificial sight better than blindness

artificial sight better than blindness but still very very simple some gloops

but still very very simple some gloops

but still very very simple some gloops groups like mine are aiming for a

groups like mine are aiming for a

groups like mine are aiming for a slightly higher quality visual

slightly higher quality visual

slightly higher quality visual prosthesis experience artificial vision

prosthesis experience artificial vision

prosthesis experience artificial vision and so we’re taking slightly longer in

and so we’re taking slightly longer in

and so we’re taking slightly longer in development other groups are seeking to

development other groups are seeking to

development other groups are seeking to deliver a device as quickly as possible

deliver a device as quickly as possible

deliver a device as quickly as possible and so have taken a lower-resolution

and so have taken a lower-resolution

and so have taken a lower-resolution path the hard part is not the

path the hard part is not the

path the hard part is not the technological design of the external

technological design of the external

technological design of the external apparatus the camera the eyeglasses the

apparatus the camera the eyeglasses the

apparatus the camera the eyeglasses the stimulator but in fact the electrodes

stimulator but in fact the electrodes

stimulator but in fact the electrodes themselves and making sure everything is

themselves and making sure everything is

themselves and making sure everything is biocompatible since putting an electrode

biocompatible since putting an electrode

biocompatible since putting an electrode in a human is a hard thing to do most of

in a human is a hard thing to do most of

in a human is a hard thing to do most of these groups rely on computerized

these groups rely on computerized

these groups rely on computerized simulations of artificial vision in

simulations of artificial vision in

simulations of artificial vision in order to answer questions about how well

order to answer questions about how well

order to answer questions about how well their device and their design will work

their device and their design will work

their device and their design will work they use virtual reality technology and

they use virtual reality technology and

they use virtual reality technology and normal sighted individuals in order to

normal sighted individuals in order to

normal sighted individuals in order to do this and these simulations are kind

do this and these simulations are kind

do this and these simulations are kind of fun so I’m going to show you two of

of fun so I’m going to show you two of

of fun so I’m going to show you two of them as an example on the left side is a

them as an example on the left side is a

them as an example on the left side is a movie of a young woman from an ordinary

movie of a young woman from an ordinary

movie of a young woman from an ordinary camera on the right will be a simulation

camera on the right will be a simulation

camera on the right will be a simulation of artificial vision with 500 phosphines

of artificial vision with 500 phosphines

of artificial vision with 500 phosphines notice a couple of things first

notice a couple of things first

notice a couple of things first those phosphenes aren’t one right next

those phosphenes aren’t one right next

those phosphenes aren’t one right next to the other like the pixels in your

to the other like the pixels in your

to the other like the pixels in your computer monitor they’re spread apart

computer monitor they’re spread apart

computer monitor they’re spread apart that’s because when we put fine wires

that’s because when we put fine wires

that’s because when we put fine wires into the brain to

into the brain to

into the brain to electrodes for visual prosthesis we have

electrodes for visual prosthesis we have

electrodes for visual prosthesis we have to space them every so often in order to

to space them every so often in order to

to space them every so often in order to not damage the brain we have to be

not damage the brain we have to be

not damage the brain we have to be clever about biocompatibility in order

clever about biocompatibility in order

clever about biocompatibility in order to maximize the number of electrodes

to maximize the number of electrodes

to maximize the number of electrodes that go in because each electrode

that go in because each electrode

that go in because each electrode produces one phosphine next notice that

produces one phosphine next notice that

produces one phosphine next notice that if I’d shown you just the right hand

if I’d shown you just the right hand

if I’d shown you just the right hand image you probably wouldn’t recognize it

image you probably wouldn’t recognize it

image you probably wouldn’t recognize it as the face of a woman watch now as the

as the face of a woman watch now as the

as the face of a woman watch now as the animation begins you can probably very

animation begins you can probably very

animation begins you can probably very quickly see that it is in fact the image

quickly see that it is in fact the image

quickly see that it is in fact the image of a woman’s face you see her eyes her

of a woman’s face you see her eyes her

of a woman’s face you see her eyes her smile you might recognize her you can

smile you might recognize her you can

smile you might recognize her you can tell that it’s a sunny day and she

tell that it’s a sunny day and she

tell that it’s a sunny day and she raises her hands against Lee against the

raises her hands against Lee against the

raises her hands against Lee against the light the brain does a marvelous

light the brain does a marvelous

light the brain does a marvelous wonderful job of assembling that

wonderful job of assembling that

wonderful job of assembling that information let me play that again the

information let me play that again the

information let me play that again the left image has about a million pixels

left image has about a million pixels

left image has about a million pixels the right image only 500 phosphines now

the right image only 500 phosphines now

the right image only 500 phosphines now 500 phosphines won’t give you normal

500 phosphines won’t give you normal

500 phosphines won’t give you normal vision not by a long shot but it’s not

vision not by a long shot but it’s not

vision not by a long shot but it’s not bad it certainly would be useful or at

bad it certainly would be useful or at

bad it certainly would be useful or at least it appears to be so here’s another

least it appears to be so here’s another

least it appears to be so here’s another example from an experiment that we have

example from an experiment that we have

example from an experiment that we have run in the laboratory to test how well

run in the laboratory to test how well

run in the laboratory to test how well artificial vision can be used to read

artificial vision can be used to read

artificial vision can be used to read there will be a simple sentence that

there will be a simple sentence that

there will be a simple sentence that will that will appear on the screen over

will that will appear on the screen over

will that will appear on the screen over three lines and you’ll hear the subject

three lines and you’ll hear the subject

three lines and you’ll hear the subject read the text out loud notice that the

read the text out loud notice that the

read the text out loud notice that the pattern of phosphines will move as she

pattern of phosphines will move as she

pattern of phosphines will move as she looks at different parts of the sentence

can different kind of flowers grow by

can different kind of flowers grow by the side of the road she normally reads

the side of the road she normally reads

the side of the road she normally reads now I bet no one could actually read

now I bet no one could actually read

now I bet no one could actually read that text but she could remember with

that text but she could remember with

that text but she could remember with the first animation that I showed you

the first animation that I showed you

the first animation that I showed you the jump between the static phosphenes

the jump between the static phosphenes

the jump between the static phosphenes and when they began to be animated

and when they began to be animated

and when they began to be animated there’s a similar jump that happens

there’s a similar jump that happens

there’s a similar jump that happens between watching someone else run an

between watching someone else run an

between watching someone else run an artificial vision simulation and running

artificial vision simulation and running

artificial vision simulation and running it yourself because the phosphenes move

it yourself because the phosphenes move

it yourself because the phosphenes move with your eyes let me play that again

can different kind of flowers grow by

can different kind of flowers grow by the side of the road she reads that

the side of the road she reads that

the side of the road she reads that woman was a typical average subject and

woman was a typical average subject and

woman was a typical average subject and she could read easily and smoothly with

she could read easily and smoothly with

she could read easily and smoothly with 1,700 phosphines

1,700 phosphines

1,700 phosphines that means that anyone here with normal

that means that anyone here with normal

that means that anyone here with normal vision would probably also be able to

vision would probably also be able to

vision would probably also be able to read the same way if we put you in front

read the same way if we put you in front

read the same way if we put you in front of the simulation there are two groups

of the simulation there are two groups

of the simulation there are two groups one in Germany one in the United States

one in Germany one in the United States

one in Germany one in the United States who have created devices that have

who have created devices that have

who have created devices that have received approval for implantation in

received approval for implantation in

received approval for implantation in blind patients although these devices

blind patients although these devices

blind patients although these devices are very promising they only provide

are very promising they only provide

are very promising they only provide very crude vision not nearly as good as

very crude vision not nearly as good as

very crude vision not nearly as good as the two simulations I showed you just

the two simulations I showed you just

the two simulations I showed you just now no one has built real devices like

now no one has built real devices like

now no one has built real devices like that yet but all of the groups are

that yet but all of the groups are

that yet but all of the groups are working hard in my laboratory we are

working hard in my laboratory we are

working hard in my laboratory we are currently testing a system that uses 128

currently testing a system that uses 128

currently testing a system that uses 128 electrodes using two of the bundles I’ve

electrodes using two of the bundles I’ve

electrodes using two of the bundles I’ve shown here and we have a newer version

shown here and we have a newer version

shown here and we have a newer version of the same thing that doubles that

of the same thing that doubles that

of the same thing that doubles that count to 250 or about half of the number

count to 250 or about half of the number

count to 250 or about half of the number of phosphenes that you saw in the first

of phosphenes that you saw in the first

of phosphenes that you saw in the first video at the same time we are designing

video at the same time we are designing

video at the same time we are designing the next generation system which will

the next generation system which will

the next generation system which will have 1,000 phosphines

have 1,000 phosphines

have 1,000 phosphines and we’ll start testing that in about a

and we’ll start testing that in about a

and we’ll start testing that in about a year we aren’t the only ones making good

year we aren’t the only ones making good

year we aren’t the only ones making good progress and I expect to hear new

progress and I expect to hear new

progress and I expect to hear new exciting results from field from groups

exciting results from field from groups

exciting results from field from groups around the world in the next while the

around the world in the next while the

around the world in the next while the message I want to leave you with

message I want to leave you with

message I want to leave you with therefore is as crazy as it might sound

therefore is as crazy as it might sound

therefore is as crazy as it might sound we’re able to put signals directly into

we’re able to put signals directly into

we’re able to put signals directly into the brain and go from 0 to infinity

the brain and go from 0 to infinity

the brain and go from 0 to infinity restoring sight to the blind thank you

restoring sight to the blind thank you

restoring sight to the blind thank you you

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