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Every breath you take: how cell barriers protect the body | Simon Jackson | TEDxTruro


my father was a translator he spoke five

my father was a translator he spoke five languages fluently and he was pretty

languages fluently and he was pretty

languages fluently and he was pretty good at lots of others as well I used to

good at lots of others as well I used to

good at lots of others as well I used to marvel when I was a child we go on

marvel when I was a child we go on

marvel when I was a child we go on holiday to different countries he could

holiday to different countries he could

holiday to different countries he could converse with different people

converse with different people

converse with different people whatever the land we were in they could

whatever the land we were in they could

whatever the land we were in they could understand him he could understand them

understand him he could understand them

understand him he could understand them sadly I didn’t inherit his linguistic

sadly I didn’t inherit his linguistic

sadly I didn’t inherit his linguistic skills but methods of communication have

skills but methods of communication have

skills but methods of communication have remained with me as a fascination

remained with me as a fascination

remained with me as a fascination throughout my life

throughout my life

throughout my life what about messages what do they convey

what about messages what do they convey

what about messages what do they convey how do we decipher them how do we act on

how do we decipher them how do we act on

how do we decipher them how do we act on the information that we get can this

the information that we get can this

the information that we get can this translate not just into humans but into

translate not just into humans but into

translate not just into humans but into other things other forms of life I was

other things other forms of life I was

other things other forms of life I was always interested in science and in

always interested in science and in

always interested in science and in particular the science of the human body

particular the science of the human body

particular the science of the human body and how the body responds to threats

and how the body responds to threats

and how the body responds to threats from the environment how do we protect

from the environment how do we protect

from the environment how do we protect ourselves from infection what are the

ourselves from infection what are the

ourselves from infection what are the cells that are used in protecting the

cells that are used in protecting the

cells that are used in protecting the body from infection the cells of the

body from infection the cells of the

body from infection the cells of the immune system

immune system

immune system so I was lucky enough to become an

so I was lucky enough to become an

so I was lucky enough to become an immunologist and now I spend my time

immunologist and now I spend my time

immunologist and now I spend my time studying those cells studying how they

studying those cells studying how they

studying those cells studying how they respond to infectious threats and other

respond to infectious threats and other

respond to infectious threats and other threats in the environment and what I’ve

threats in the environment and what I’ve

threats in the environment and what I’ve learnt is a key component of how the

learnt is a key component of how the

learnt is a key component of how the immune system responds is the

immune system responds is the

immune system responds is the communication between the cells the

communication between the cells the

communication between the cells the cells are speaking to each other and

cells are speaking to each other and

cells are speaking to each other and that’s how we manifest our defense of

that’s how we manifest our defense of

that’s how we manifest our defense of the body let’s think about the lungs

the body let’s think about the lungs

the body let’s think about the lungs I’ve become very interested in the

I’ve become very interested in the

I’ve become very interested in the immune system in the lungs now I hope

immune system in the lungs now I hope

immune system in the lungs now I hope you’re all still breathing yeah we

you’re all still breathing yeah we

you’re all still breathing yeah we haven’t lost anybody yet that’s good

haven’t lost anybody yet that’s good

haven’t lost anybody yet that’s good every time you breathe you’re breathing

every time you breathe you’re breathing

every time you breathe you’re breathing in and out about a half a liter of air

in and out about a half a liter of air

in and out about a half a liter of air that equates to about 10,000 liters of

that equates to about 10,000 liters of

that equates to about 10,000 liters of air that pass through our lungs every

air that pass through our lungs every

air that pass through our lungs every day

everything in the air

everything in the air we’re breathing and let’s think about

we’re breathing and let’s think about

we’re breathing and let’s think about the challenges that poses to the lungs

the challenges that poses to the lungs

the challenges that poses to the lungs and in particular I want to tell you

and in particular I want to tell you

and in particular I want to tell you about a group of cells called epithelial

about a group of cells called epithelial

about a group of cells called epithelial cells these are cells that form the

cells these are cells that form the

cells these are cells that form the barrier in the lungs between the body

barrier in the lungs between the body

barrier in the lungs between the body the lungs themselves and the external

the lungs themselves and the external

the lungs themselves and the external environment the air that we are

environment the air that we are

environment the air that we are breathing and if you think about it they

breathing and if you think about it they

breathing and if you think about it they have a very very challenging job to do

have a very very challenging job to do

have a very very challenging job to do because yes we want to keep out noxious

because yes we want to keep out noxious

because yes we want to keep out noxious particles viruses and bacteria so they

particles viruses and bacteria so they

particles viruses and bacteria so they have to be able to do that but also they

have to be able to do that but also they

have to be able to do that but also they have to allow us to exchange the gases

have to allow us to exchange the gases

have to allow us to exchange the gases that we need for life every time we

that we need for life every time we

that we need for life every time we breathe in we’re taking a little little

breathe in we’re taking a little little

breathe in we’re taking a little little oxygen from the air we breathe and we’re

oxygen from the air we breathe and we’re

oxygen from the air we breathe and we’re returning a bit of carbon dioxide so

returning a bit of carbon dioxide so

returning a bit of carbon dioxide so these barrier cells are actually very

these barrier cells are actually very

these barrier cells are actually very useful to us these epithelial cells that

useful to us these epithelial cells that

useful to us these epithelial cells that act as barriers there allow us to

act as barriers there allow us to

act as barriers there allow us to exchange gases and they must protect us

exchange gases and they must protect us

exchange gases and they must protect us they must keep the outside out and the

they must keep the outside out and the

they must keep the outside out and the inside in and for a long time that’s all

inside in and for a long time that’s all

inside in and for a long time that’s all we thought they did we just thought they

we thought they did we just thought they

we thought they did we just thought they were barriers that they didn’t have much

were barriers that they didn’t have much

were barriers that they didn’t have much other functioning now we know of course

other functioning now we know of course

other functioning now we know of course that they do and in fact a key part of

that they do and in fact a key part of

that they do and in fact a key part of how they protect us from the outside

how they protect us from the outside

how they protect us from the outside environment how they maintain the

environment how they maintain the

environment how they maintain the integrity of the lungs how they keep us

integrity of the lungs how they keep us

integrity of the lungs how they keep us free from infection is that they

free from infection is that they

free from infection is that they communicate with other cells and some of

communicate with other cells and some of

communicate with other cells and some of the important cells that they

the important cells that they

the important cells that they communicate with are called macrophages

communicate with are called macrophages

communicate with are called macrophages that literally means cells that go

that literally means cells that go

that literally means cells that go around eating things they’re big eaters

around eating things they’re big eaters

around eating things they’re big eaters and the epithelial cells tell the

and the epithelial cells tell the

and the epithelial cells tell the macrophages what’s in the environment

macrophages what’s in the environment

macrophages what’s in the environment they send signals they communicate with

they send signals they communicate with

they send signals they communicate with the environment they send signals to the

the environment they send signals to the

the environment they send signals to the macrophages so that if there’s an

macrophages so that if there’s an

macrophages so that if there’s an infection coming if there’s a bacteria

infection coming if there’s a bacteria

infection coming if there’s a bacteria they’ve encountered for exam

they’ve encountered for exam

they’ve encountered for exam the macrophages become activated to deal

the macrophages become activated to deal

the macrophages become activated to deal with that threat and we call these

with that threat and we call these

with that threat and we call these activated macrophages M 1 as

activated macrophages M 1 as

activated macrophages M 1 as immunologists we’re not very imaginative

immunologists we’re not very imaginative

immunologists we’re not very imaginative so these are M 1 and they’re very

so these are M 1 and they’re very

so these are M 1 and they’re very aggressive they’re spoiling for a fight

aggressive they’re spoiling for a fight

aggressive they’re spoiling for a fight they’ll kick the hell out of bacteria

they’ll kick the hell out of bacteria

they’ll kick the hell out of bacteria but of course they might damage the

but of course they might damage the

but of course they might damage the surrounding just like in a bar brawl

surrounding just like in a bar brawl

surrounding just like in a bar brawl lots of windows get smashed so they take

lots of windows get smashed so they take

lots of windows get smashed so they take out the invaders but they can cause

out the invaders but they can cause

out the invaders but they can cause damage so we have to limit their

damage so we have to limit their

damage so we have to limit their aggression and so the barrier cells also

aggression and so the barrier cells also

aggression and so the barrier cells also have to send signals to macrophages to

have to send signals to macrophages to

have to send signals to macrophages to calm them down and in their calm state

calm them down and in their calm state

calm them down and in their calm state they’re chilled out state they’re known

they’re chilled out state they’re known

they’re chilled out state they’re known as m2 again very imaginative

as m2 again very imaginative

as m2 again very imaginative so the m2 macrophages are laid-back and

so the m2 macrophages are laid-back and

so the m2 macrophages are laid-back and what they do is they stop the m1

what they do is they stop the m1

what they do is they stop the m1 macrophages from being aggressive and

macrophages from being aggressive and

macrophages from being aggressive and the m2 macrophages go in and they repair

the m2 macrophages go in and they repair

the m2 macrophages go in and they repair any damages done they repair that

any damages done they repair that

any damages done they repair that barrier those epithelial cells clearly

barrier those epithelial cells clearly

barrier those epithelial cells clearly the signaling between the epithelial

the signaling between the epithelial

the signaling between the epithelial cells and the macrophages is very

cells and the macrophages is very

cells and the macrophages is very important and sometimes the macrophages

important and sometimes the macrophages

important and sometimes the macrophages return the favor they signal back to the

return the favor they signal back to the

return the favor they signal back to the epithelial cells as we shall see a bit

epithelial cells as we shall see a bit

epithelial cells as we shall see a bit later on they can instruct the

later on they can instruct the

later on they can instruct the epithelial cells to do things but this

epithelial cells to do things but this

epithelial cells to do things but this communication between the cells

communication between the cells

communication between the cells regulates the activity and it keeps us

regulates the activity and it keeps us

regulates the activity and it keeps us healthy it keeps our lungs healthy as we

healthy it keeps our lungs healthy as we

healthy it keeps our lungs healthy as we breathe we breathe in everything in the

breathe we breathe in everything in the

breathe we breathe in everything in the air particles of soot bacteria people

air particles of soot bacteria people

air particles of soot bacteria people coughing viruses diesel particles

coughing viruses diesel particles

coughing viruses diesel particles organic matter everything in the air

organic matter everything in the air

organic matter everything in the air that we are breathing passes into our

that we are breathing passes into our

that we are breathing passes into our lungs and of course that can cause

lungs and of course that can cause

lungs and of course that can cause damage to the lungs if we know how the

damage to the lungs if we know how the

damage to the lungs if we know how the damage is caused and perhaps which

damage is caused and perhaps which

damage is caused and perhaps which pollutants are causing that damage then

pollutants are causing that damage then

pollutants are causing that damage then maybe we can do something about it and

maybe we can do something about it and

maybe we can do something about it and the World Health Organization tell us

the World Health Organization tell us

the World Health Organization tell us that in the past year over 7 million

that in the past year over 7 million

that in the past year over 7 million people have died from air

people have died from air

people have died from air that’s about one in eight of the total

that’s about one in eight of the total

that’s about one in eight of the total deaths in the world is due to breathing

deaths in the world is due to breathing

deaths in the world is due to breathing polluted and contaminated air and that’s

polluted and contaminated air and that’s

polluted and contaminated air and that’s a problem

a problem

a problem in our country and particularly in many

in our country and particularly in many

in our country and particularly in many of the developing countries around the

of the developing countries around the

of the developing countries around the world pollutants can corrupt the

world pollutants can corrupt the

world pollutants can corrupt the signaling between those cells pollutants

signaling between those cells pollutants

signaling between those cells pollutants very often can activate the em1 those

very often can activate the em1 those

very often can activate the em1 those aggressive macrophages and keep them

aggressive macrophages and keep them

aggressive macrophages and keep them switched on so we get lots of damage as

switched on so we get lots of damage as

switched on so we get lots of damage as a result of course we can get chronic

a result of course we can get chronic

a result of course we can get chronic diseases asthma COPD chronic obstructive

diseases asthma COPD chronic obstructive

diseases asthma COPD chronic obstructive pulmonary disease and many others that

pulmonary disease and many others that

pulmonary disease and many others that caused the deaths that we see due to air

caused the deaths that we see due to air

caused the deaths that we see due to air pollution other pollutants can activate

pollution other pollutants can activate

pollution other pollutants can activate the m-2 macrophages and keep them

the m-2 macrophages and keep them

the m-2 macrophages and keep them switched on and what can happen then is

switched on and what can happen then is

switched on and what can happen then is we get aberrant thickening of the

we get aberrant thickening of the

we get aberrant thickening of the epithelial cells and we might leave

epithelial cells and we might leave

epithelial cells and we might leave ourselves open to infection from

ourselves open to infection from

ourselves open to infection from bacteria and from viruses if we can

bacteria and from viruses if we can

bacteria and from viruses if we can understand those signals if we can

understand those signals if we can

understand those signals if we can understand the language between the

understand the language between the

understand the language between the epithelial cells and the macrophages and

epithelial cells and the macrophages and

epithelial cells and the macrophages and how the pollutants can corrupt that

how the pollutants can corrupt that

how the pollutants can corrupt that language then maybe we can start to do

language then maybe we can start to do

language then maybe we can start to do something about it

something about it

something about it and that’s the task that I set myself

and that’s the task that I set myself

and that’s the task that I set myself and my research group now the first

and my research group now the first

and my research group now the first thing to do of course is to find some

thing to do of course is to find some

thing to do of course is to find some lungs we want to work on this signaling

lungs we want to work on this signaling

lungs we want to work on this signaling between epithelial cells barrier cells

between epithelial cells barrier cells

between epithelial cells barrier cells in the lungs and immune cells the

in the lungs and immune cells the

in the lungs and immune cells the macrophages that interact with them so

macrophages that interact with them so

macrophages that interact with them so I’d like volunteer to donate some of

I’d like volunteer to donate some of

I’d like volunteer to donate some of their lungs it’s all in a good cause in

their lungs it’s all in a good cause in

their lungs it’s all in a good cause in science yeah I usually get that response

science yeah I usually get that response

science yeah I usually get that response not too many people want to give me some

not too many people want to give me some

not too many people want to give me some of their lungs actually there are some

of their lungs actually there are some

of their lungs actually there are some people that do and there’s a technique

people that do and there’s a technique

people that do and there’s a technique called bronchoalveolar lavage where you

called bronchoalveolar lavage where you

called bronchoalveolar lavage where you put a salt solution into the lungs and

put a salt solution into the lungs and

put a salt solution into the lungs and you wash out the lungs and with that

you wash out the lungs and with that

you wash out the lungs and with that comes some cells and we can grow the

comes some cells and we can grow the

comes some cells and we can grow the cells but we don’t really want to do

cells but we don’t really want to do

cells but we don’t really want to do that it’s a bit of an inconvenience and

that it’s a bit of an inconvenience and

that it’s a bit of an inconvenience and I wouldn’t recommend that you volunteer

I wouldn’t recommend that you volunteer

I wouldn’t recommend that you volunteer for that

for that

for that frankly what we’ve done is developed

frankly what we’ve done is developed

frankly what we’ve done is developed cells that grow continuously but are

cells that grow continuously but are

cells that grow continuously but are actually very very much like the

actually very very much like the

actually very very much like the alveolar epithelial cells and

alveolar epithelial cells and

alveolar epithelial cells and macrophages the cells of the lung that

macrophages the cells of the lung that

macrophages the cells of the lung that we want to study we can grow these soul

we want to study we can grow these soul

we want to study we can grow these soul cells together in special chambers in

cells together in special chambers in

cells together in special chambers in the lab so they’re like a lab lung so

the lab so they’re like a lab lung so

the lab so they’re like a lab lung so now we have a system that we can

now we have a system that we can

now we have a system that we can interrogate we can put different

interrogate we can put different

interrogate we can put different pollutants into that system and that’s

pollutants into that system and that’s

pollutants into that system and that’s what we’re doing we can add extracts

what we’re doing we can add extracts

what we’re doing we can add extracts from diesel exhaust particles we can add

from diesel exhaust particles we can add

from diesel exhaust particles we can add allergens we can add organic matter

allergens we can add organic matter

allergens we can add organic matter that’s come from composting or intensive

that’s come from composting or intensive

that’s come from composting or intensive agriculture sites that’s exactly what

agriculture sites that’s exactly what

agriculture sites that’s exactly what we’re doing and we’re looking at the

we’re doing and we’re looking at the

we’re doing and we’re looking at the responses that the macrophages have are

responses that the macrophages have are

responses that the macrophages have are they aggressive are they chilled out

they aggressive are they chilled out

they aggressive are they chilled out are they m1 are they m2 what’s happening

are they m1 are they m2 what’s happening

are they m1 are they m2 what’s happening to the epithelial cells we can study all

to the epithelial cells we can study all

to the epithelial cells we can study all these things in this lab lung that we’ve

these things in this lab lung that we’ve

these things in this lab lung that we’ve got now the cells don’t talk to each

got now the cells don’t talk to each

got now the cells don’t talk to each other using words would be great if they

other using words would be great if they

other using words would be great if they did but they talk to each other by

did but they talk to each other by

did but they talk to each other by producing small proteins those proteins

producing small proteins those proteins

producing small proteins those proteins are called cytokines so if we can

are called cytokines so if we can

are called cytokines so if we can identify those proteins that would be

identify those proteins that would be

identify those proteins that would be like identifying the language and then

like identifying the language and then

like identifying the language and then we could translate what they were saying

we could translate what they were saying

we could translate what they were saying we could understand the language of the

we could understand the language of the

we could understand the language of the cells so that’s what we need to do and

cells so that’s what we need to do and

cells so that’s what we need to do and that’s what we’ve been doing we’ve been

that’s what we’ve been doing we’ve been

that’s what we’ve been doing we’ve been taking samples from our lab lung our

taking samples from our lab lung our

taking samples from our lab lung our cell cultures that have had different

cell cultures that have had different

cell cultures that have had different stimulants added to them different

stimulants added to them different

stimulants added to them different pollutants and we’ve taken the mixture

pollutants and we’ve taken the mixture

pollutants and we’ve taken the mixture containing all the proteins that these

containing all the proteins that these

containing all the proteins that these cells are communicating to each other

cells are communicating to each other

cells are communicating to each other with and we we’re trying to identify

with and we we’re trying to identify

with and we we’re trying to identify what they are sometimes the macrophages

what they are sometimes the macrophages

what they are sometimes the macrophages talk back to the epithelial cells and if

talk back to the epithelial cells and if

talk back to the epithelial cells and if there are particular stresses in the

there are particular stresses in the

there are particular stresses in the environment the macrophages instruct the

environment the macrophages instruct the

environment the macrophages instruct the epithelial cells to commit suicide it’s

epithelial cells to commit suicide it’s

epithelial cells to commit suicide it’s a process called apoptosis

now sometimes this can be actually

now sometimes this can be actually beneficial but of course many times it

beneficial but of course many times it

beneficial but of course many times it can be detrimental and if you look at

can be detrimental and if you look at

can be detrimental and if you look at the difference between the the pictures

the difference between the the pictures

the difference between the the pictures the micrographs that you can see on the

the micrographs that you can see on the

the micrographs that you can see on the slides you can see that on the left

slides you can see that on the left

slides you can see that on the left you’ve got a nice mixture of macrophages

you’ve got a nice mixture of macrophages

you’ve got a nice mixture of macrophages and epithelial cells but the main

and epithelial cells but the main

and epithelial cells but the main difference is on the right that many of

difference is on the right that many of

difference is on the right that many of those cells have disappeared those are

those cells have disappeared those are

those cells have disappeared those are the epithelial cells that have committed

the epithelial cells that have committed

the epithelial cells that have committed suicide under instruction from the

suicide under instruction from the

suicide under instruction from the macrophages so we’re interested in what

macrophages so we’re interested in what

macrophages so we’re interested in what those signals are as well what’s that

those signals are as well what’s that

those signals are as well what’s that language okay to understand a language

language okay to understand a language

language okay to understand a language we need a translator just much like when

we need a translator just much like when

we need a translator just much like when we started I told you about my father

we started I told you about my father

we started I told you about my father translating languages we have to have a

translating languages we have to have a

translating languages we have to have a translator that can understand the

translator that can understand the

translator that can understand the protein language that the cells are

protein language that the cells are

protein language that the cells are speaking to each other

speaking to each other

speaking to each other we have to be able to take all the

we have to be able to take all the

we have to be able to take all the proteins in our system put it through a

proteins in our system put it through a

proteins in our system put it through a translator and hopefully some sensible

translator and hopefully some sensible

translator and hopefully some sensible sentences might come out the other end

sentences might come out the other end

sentences might come out the other end and to do that we use sophisticated

and to do that we use sophisticated

and to do that we use sophisticated equipment called a mass spectrometer

equipment called a mass spectrometer

equipment called a mass spectrometer what this does is it smashes up all the

what this does is it smashes up all the

what this does is it smashes up all the proteins into tiny fragments and then it

proteins into tiny fragments and then it

proteins into tiny fragments and then it separates those fragments according to

separates those fragments according to

separates those fragments according to their mass and it turns out that the

their mass and it turns out that the

their mass and it turns out that the mass of the fragments are unique to

mass of the fragments are unique to

mass of the fragments are unique to different proteins so if we can identify

different proteins so if we can identify

different proteins so if we can identify the fragments from their masses we can

the fragments from their masses we can

the fragments from their masses we can work back and tell which proteins are

work back and tell which proteins are

work back and tell which proteins are present and that’s exactly what we’re

present and that’s exactly what we’re

present and that’s exactly what we’re doing we’re looking at all the proteins

doing we’re looking at all the proteins

doing we’re looking at all the proteins in our system something called

in our system something called

in our system something called proteomics we’re analyzing that and then

proteomics we’re analyzing that and then

proteomics we’re analyzing that and then deciphering what proteins are produced

deciphering what proteins are produced

deciphering what proteins are produced under different conditions what

under different conditions what

under different conditions what pollutants are inducing certain proteins

pollutants are inducing certain proteins

pollutants are inducing certain proteins and what’s the response from our

and what’s the response from our

and what’s the response from our macrophages so this is the language of

macrophages so this is the language of

macrophages so this is the language of the cells this is the protein language

the cells this is the protein language

the cells this is the protein language of the cells it turns out the protein

of the cells it turns out the protein

of the cells it turns out the protein language is quite complex but we’re

language is quite complex but we’re

language is quite complex but we’re starting to understand it we’ve got a

starting to understand it we’ve got a

starting to understand it we’ve got a rudimentary understanding of the

rudimentary understanding of the

rudimentary understanding of the language of the cells and this will

language of the cells and this will

language of the cells and this will allow us to make predictions about how

allow us to make predictions about how

allow us to make predictions about how the cells might respond in different

the cells might respond in different

the cells might respond in different situations

situations

situations so what if we found out we’ve been able

so what if we found out we’ve been able

so what if we found out we’ve been able to grow lung cells in the lab we’ve been

to grow lung cells in the lab we’ve been

to grow lung cells in the lab we’ve been able to add different stimulants

able to add different stimulants

able to add different stimulants different pollutants to these lung cells

different pollutants to these lung cells

different pollutants to these lung cells and we’ve been able to look at whether

and we’ve been able to look at whether

and we’ve been able to look at whether they induce the aggressive m1

they induce the aggressive m1

they induce the aggressive m1 macrophages or the chilled-out m2

macrophages or the chilled-out m2

macrophages or the chilled-out m2 macrophages and how that impacts on the

macrophages and how that impacts on the

macrophages and how that impacts on the barrier cells we’ve been able to find

barrier cells we’ve been able to find

barrier cells we’ve been able to find out some of the protein language that

out some of the protein language that

out some of the protein language that instructs the aggressive m1 macrophage

instructs the aggressive m1 macrophage

instructs the aggressive m1 macrophage or the chilled-out m2 macrophage and

or the chilled-out m2 macrophage and

or the chilled-out m2 macrophage and this is allowing us to develop drugs

this is allowing us to develop drugs

this is allowing us to develop drugs that can maybe change that language so

that can maybe change that language so

that can maybe change that language so that when we’re faced with pollutants or

that when we’re faced with pollutants or

that when we’re faced with pollutants or other stresses that switch on the

other stresses that switch on the

other stresses that switch on the aggressive m1 we can change that

aggressive m1 we can change that

aggressive m1 we can change that language we can modify it back to a

language we can modify it back to a

language we can modify it back to a language it tells them to to chill out

language it tells them to to chill out

language it tells them to to chill out of it so we might be able to treat or

of it so we might be able to treat or

of it so we might be able to treat or even prevent diseases such as asthma and

even prevent diseases such as asthma and

even prevent diseases such as asthma and other airway diseases the more we

other airway diseases the more we

other airway diseases the more we understand about this language this

understand about this language this

understand about this language this protein language of the cells and more

protein language of the cells and more

protein language of the cells and more than that our mini lung is also we can

than that our mini lung is also we can

than that our mini lung is also we can work the ank language back the other way

work the ank language back the other way

work the ank language back the other way we can look at what it’s telling us and

we can look at what it’s telling us and

we can look at what it’s telling us and then understand what’s in the

then understand what’s in the

then understand what’s in the environment around us what is in the air

environment around us what is in the air

environment around us what is in the air around us so we’re using our cells as

around us so we’re using our cells as

around us so we’re using our cells as sensors to tell us what’s around every

sensors to tell us what’s around every

sensors to tell us what’s around every breath we take

breath we take

breath we take so please think about the language of

so please think about the language of

so please think about the language of the cells with every breath you take

the cells with every breath you take

the cells with every breath you take thank you

thank you

thank you [Applause]

”

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