[Applause] when you sit in front of your doctor
when you sit in front of your doctor
when you sit in front of your doctor your doctor cannot know what treatment
your doctor cannot know what treatment
your doctor cannot know what treatment will work for you I was shocked when I
will work for you I was shocked when I
will work for you I was shocked when I found out in the first place for almost
found out in the first place for almost
found out in the first place for almost half of medical treatments in use there
half of medical treatments in use there
half of medical treatments in use there is no proof of effect effectivity at all
is no proof of effect effectivity at all
is no proof of effect effectivity at all this was shown in a famous study that
this was shown in a famous study that
this was shown in a famous study that was published in the British Medical
was published in the British Medical
was published in the British Medical Journal so for one in two treatments
Journal so for one in two treatments
Journal so for one in two treatments nobody has ever shown that they really
nobody has ever shown that they really
nobody has ever shown that they really make you better when you get sick and
make you better when you get sick and
make you better when you get sick and the proof for the other half of the
the proof for the other half of the
the proof for the other half of the treatments is based on only a fraction
treatments is based on only a fraction
treatments is based on only a fraction of the patient population so the
of the patient population so the
of the patient population so the research is based on young white healthy
research is based on young white healthy
research is based on young white healthy meals while on the Netherlands alone we
meals while on the Netherlands alone we
meals while on the Netherlands alone we have 5.3 million chronic patients 1.9
have 5.3 million chronic patients 1.9
have 5.3 million chronic patients 1.9 million patients with migration
million patients with migration
million patients with migration background and over half a million
background and over half a million
background and over half a million people older than 75 using more than
people older than 75 using more than
people older than 75 using more than five medications at the same time and
five medications at the same time and
five medications at the same time and these are the patients that are hardest
these are the patients that are hardest
these are the patients that are hardest to treat and furthermore the results of
to treat and furthermore the results of
to treat and furthermore the results of studies are based on averages but
studies are based on averages but
studies are based on averages but treatments have different effects on
treatments have different effects on
treatments have different effects on every unique human body and 50% of
every unique human body and 50% of
every unique human body and 50% of medical studies give different results
medical studies give different results
medical studies give different results when they are reproduced so how can a
when they are reproduced so how can a
when they are reproduced so how can a doctor trust research so a doctor does
doctor trust research so a doctor does
doctor trust research so a doctor does not have access to the right information
not have access to the right information
not have access to the right information but what does this mean this means that
but what does this mean this means that
but what does this mean this means that people stay sick when they don’t have to
people stay sick when they don’t have to
people stay sick when they don’t have to but it can also mean that people die
but it can also mean that people die
but it can also mean that people die according to professor Goucher who is
according to professor Goucher who is
according to professor Goucher who is one of the founders of the Cochrane
one of the founders of the Cochrane
one of the founders of the Cochrane Collaboration
Collaboration
Collaboration the wrongful effects of medication is
the wrongful effects of medication is
the wrongful effects of medication is not a third leading cause of death in
not a third leading cause of death in
not a third leading cause of death in the United States and Western Europe we
the United States and Western Europe we
the United States and Western Europe we in September 2014 but we both
in September 2014 but we both
in September 2014 but we both participated in the Dutch national think
participated in the Dutch national think
participated in the Dutch national think tank on big data we immediately found
tank on big data we immediately found
tank on big data we immediately found each other in a shared conviction and
each other in a shared conviction and
each other in a shared conviction and from that moment on we spent all our
from that moment on we spent all our
from that moment on we spent all our time on it our conviction is that we can
time on it our conviction is that we can
time on it our conviction is that we can use the digitization of the world to
use the digitization of the world to
use the digitization of the world to make healthcare smarter and much much
make healthcare smarter and much much
make healthcare smarter and much much better I studied medicine I’ve learned
better I studied medicine I’ve learned
better I studied medicine I’ve learned how the human body works I’ve seen our
how the human body works I’ve seen our
how the human body works I’ve seen our medical research is done and I’ve seen
medical research is done and I’ve seen
medical research is done and I’ve seen our doctors have to make their decisions
our doctors have to make their decisions
our doctors have to make their decisions and I’m a theoretical physicist and I’ve
and I’m a theoretical physicist and I’ve
and I’m a theoretical physicist and I’ve always wanted to use my analytical
always wanted to use my analytical
always wanted to use my analytical skills to have true impact on the real
skills to have true impact on the real
skills to have true impact on the real ever faster changing world and we would
ever faster changing world and we would
ever faster changing world and we would like to see a world where there’s proof
like to see a world where there’s proof
like to see a world where there’s proof of activity for every treatment and that
of activity for every treatment and that
of activity for every treatment and that every single decision in healthcare is
every single decision in healthcare is
every single decision in healthcare is based on solid evidence and this is
based on solid evidence and this is
based on solid evidence and this is possible in the digital age where
possible in the digital age where
possible in the digital age where doctors are generating more and more
doctors are generating more and more
doctors are generating more and more data each day this gives us the
data each day this gives us the
data each day this gives us the opportunity to learn from every single
opportunity to learn from every single
opportunity to learn from every single patient including children women elderly
patient including children women elderly
patient including children women elderly ethnic minorities and the millions of
ethnic minorities and the millions of
ethnic minorities and the millions of patients with multiple diseases and
patients with multiple diseases and
patients with multiple diseases and medications and we analyze from all
medications and we analyze from all
medications and we analyze from all these patients which patients are
these patients which patients are
these patients which patients are similar to you because you are not an
similar to you because you are not an
similar to you because you are not an average patient and we learned what
average patient and we learned what
average patient and we learned what treatment will work for you based on the
treatment will work for you based on the
treatment will work for you based on the success of treatments in practice for
success of treatments in practice for
success of treatments in practice for similar patients this is about gathering
similar patients this is about gathering
similar patients this is about gathering much more information from many more
much more information from many more
much more information from many more patients and processing it in a way such
patients and processing it in a way such
patients and processing it in a way such that it allows doctors to do better what
that it allows doctors to do better what
that it allows doctors to do better what makes them so valuable and irreplaceable
makes them so valuable and irreplaceable
makes them so valuable and irreplaceable which is combining different forms of
which is combining different forms of
which is combining different forms of information with the knowledge and
information with the knowledge and
information with the knowledge and experience and making a decision that
experience and making a decision that
experience and making a decision that fits with the personal situation of
fits with the personal situation of
fits with the personal situation of their patients and using data we can
their patients and using data we can
their patients and using data we can learn from the experience of patients as
learn from the experience of patients as
learn from the experience of patients as many times as we want it costs only
many times as we want it costs only
many times as we want it costs only pennies in seconds to do with
pennies in seconds to do with
pennies in seconds to do with tailor-made research and the results are
tailor-made research and the results are
tailor-made research and the results are based on up-to-date information
based on up-to-date information
based on up-to-date information directly benefit doctor and patient and
directly benefit doctor and patient and
directly benefit doctor and patient and by presenting the expected outcomes for
by presenting the expected outcomes for
by presenting the expected outcomes for an individual patient we provide the
an individual patient we provide the
an individual patient we provide the doctor with all the information he needs
doctor with all the information he needs
doctor with all the information he needs to choose the treatment that will truly
to choose the treatment that will truly
to choose the treatment that will truly benefit his patients lives and the best
benefit his patients lives and the best
benefit his patients lives and the best thing about this tooling is that it
thing about this tooling is that it
thing about this tooling is that it learns and improves every time it is
learns and improves every time it is
learns and improves every time it is used we’ve experienced that without
used we’ve experienced that without
used we’ve experienced that without medical knowledge you cannot learn
medical knowledge you cannot learn
medical knowledge you cannot learn anything from medical data that’s why
anything from medical data that’s why
anything from medical data that’s why we’ve been spending most of our time
we’ve been spending most of our time
we’ve been spending most of our time working together with both medical
working together with both medical
working together with both medical experts and doctors big data and Alethea
experts and doctors big data and Alethea
experts and doctors big data and Alethea truly is about combining the best of
truly is about combining the best of
truly is about combining the best of both worlds yeah and big data and
both worlds yeah and big data and
both worlds yeah and big data and healthcare truly is like teenage sex
healthcare truly is like teenage sex
healthcare truly is like teenage sex because everybody is talking about it
because everybody is talking about it
because everybody is talking about it everybody wants to do it everybody is
everybody wants to do it everybody is
everybody wants to do it everybody is saying that they are doing it but nobody
saying that they are doing it but nobody
saying that they are doing it but nobody is actually doing
so we wanted to choose a starting point
so we wanted to choose a starting point where we could be of help for doctor and
where we could be of help for doctor and
where we could be of help for doctor and patient starting from today so we chose
patient starting from today so we chose
patient starting from today so we chose bladder infections up until now doctors
bladder infections up until now doctors
bladder infections up until now doctors have been basing their decisions on
have been basing their decisions on
have been basing their decisions on seventeen-year-old research based on
seventeen-year-old research based on
seventeen-year-old research based on about 400 patients a time whom are all
about 400 patients a time whom are all
about 400 patients a time whom are all relatively healthy female patients it’s
relatively healthy female patients it’s
relatively healthy female patients it’s because 3 months to analyze recent data
because 3 months to analyze recent data
because 3 months to analyze recent data of over 250,000 bladder infections
of over 250,000 bladder infections
of over 250,000 bladder infections including 12,000 pregnant females over
including 12,000 pregnant females over
including 12,000 pregnant females over 80,000 elderly and over 50,000 men we
80,000 elderly and over 50,000 men we
80,000 elderly and over 50,000 men we have shown that even for one of the most
have shown that even for one of the most
have shown that even for one of the most simple and common diseases we can
simple and common diseases we can
simple and common diseases we can provide doctors with new and solid
provide doctors with new and solid
provide doctors with new and solid evidence to base their decisions on so
evidence to base their decisions on so
evidence to base their decisions on so we radically transformed the way we
we radically transformed the way we
we radically transformed the way we learn what treatment will work for whom
learn what treatment will work for whom
learn what treatment will work for whom but it feels like a very small step to
but it feels like a very small step to
but it feels like a very small step to us because for now we’ve only been using
us because for now we’ve only been using
us because for now we’ve only been using medical files that doctors have been
medical files that doctors have been
medical files that doctors have been generating for years but there’s a
generating for years but there’s a
generating for years but there’s a tsunami of information coming our way
tsunami of information coming our way
tsunami of information coming our way it’s data of increasing quality all
it’s data of increasing quality all
it’s data of increasing quality all medical devices gather very valuable
medical devices gather very valuable
medical devices gather very valuable information we generate generate
information we generate generate
information we generate generate terabytes of dinah data of CT scans mris
terabytes of dinah data of CT scans mris
terabytes of dinah data of CT scans mris patient genomics and patients themselves
patient genomics and patients themselves
patient genomics and patients themselves track their sickness and health through
track their sickness and health through
track their sickness and health through a lot of wearables and apps our dream is
a lot of wearables and apps our dream is
a lot of wearables and apps our dream is to make the doctor the point of
to make the doctor the point of
to make the doctor the point of convergence of all this information such
convergence of all this information such
convergence of all this information such that you get a treatment that works for
that you get a treatment that works for
that you get a treatment that works for you thank you
you thank you
you thank you [Applause]
”
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