you know who he is or mons
the owner of the aero company
spatial spacex that today is the
first private company that competes with
the nasa in the race of the conquest
of space have been raised a
vital issue in your trip in the
planning your trip to Mars that
let’s go on board that represents the
minimum volume and minimum weight the
cost is within our organism
of our body and are the cells
mother
our patients continue to suffer
strokes are still dying of heart attacks and
we continue to amputate them unfortunately
especially those who go wrong
present arterial disease
peripheral lately when I go from
congress
I have the feeling that if maybe
we have improved our therapies
maybe we do surgeries minimally
invasive
maybe we have talk every day of
smallest extensor catheters
that release prosthetic drugs
folding that are placed inside
devices that allow us to solve
aneurysms with a simple cut cited in
English without having to do those
surgeries that maybe you all have
in mind that they need to open the
belly and that make our
patients have to go to the office
and all other paraphernalia as well
well leaving the congresses always to
out thinking really is like
we were circling it
really question our patients
you all know that diseases
cardiovascular diseases are the first cause of
death in the western world and so
There is so much that we are not doing
all right
this feeling was confirmed when
I met paco vidal
here it is
paco vidal is a bioengineer and he
they presented a day at the clinic
drinking a coffee
it was that one big day was the second
person in a short time who was talking to me about
stem cells had a few months
stayed with a friend of the faculty and I
he was talking the satisfiers
explaining how satisfying it was for
he started his doctoral thesis bn
precisely about stem cells
the staff to the monologue and the cia in rule
in paco vidal macular degeneration
he began to explain to me what was the
transplant the autotransplant with
stem cells and he explained to me that it was a
alternative to the therapies that
we were doing
the vascular surgeons and besides already
there was an article here what
you have that had been published in the
lancet magazine in the year 2002
in this article that was presented the
study that a group had made
German in patients with ischemia
criticism that means they do not have
year contributions in a limb that does not
they had therapeutic alternative that did not
they were inoperable and that therefore
they were condemned to an amputation
in this study they had saved
legs and I think some arm too
and Paco explained that the autotransplant
with stem cells as the cells are
our own cells really was
something very simple to do that in addition
I had the problem of rejection and
nor toxicity problems like
they had the drugs and that day and
He also offered me the possibility of
start doing a study in our
center
I did not think for a second and it was real
I said yes and it was exciting to be able to
perform it
I remember well the first case we did
I remember the name and surnames
of the patient and I also remember that
is what I thought when I left the
clinic inside my car told me
montse you have noticed what you’ve done
done and we’ve really done this
treatment so simple that it is possible
that this the knowledge of the cells
mother this therapeutic application what
changed everything and good to think will think
and which are stem cells because here
they were presented there are different
forms there are cells that are stellate
there are more finger round cells but
they are all rough diamonds
Why do I say this as because they are
cells that are poorly differentiated
that we have in the adult organism and that
in certain situations they are activated and
allow you to regenerate tissues where
we found these cells because the
we find in the tissues in what
we call a niche that is lynched
a reserve of cells that are
differentiated stem cells that
They are usually around
glasses we also find them in the
peripheral blood but especially in
large number at the bone marrow level
the bone marrow is a large factory of
cells
here we have them we have cells of the
hematopoietic lineage which are the
cells that are precursors of the
red blood cells and platelets
we have dermal cells or
mesenchymal that have you this way
starry that are the forerunners of the
cartilage the bones the vessels we have
dermal cells that are the
precursors of the skin of neurons and
we also have cells in thermal
which are the precursors of the line
germline which are the cells
precursors of sperm cough and
of the oocytes
Lastly we also have the
immune cells that are
those that form our defenses
they are all in the bone marrow and
we are mobilized have a great
therapeutic potential and we know that it
mobilized by proteins and by a
system of receivers that have the
cells when the body suffers a
injury
for example a trauma a wound
to avoid bleeding for example
when we get hurt, they come to
to the injured tissue and repairs it too
in a situation of acute inflammation
this whole system is put in place to
repair the damage produced by
example for an infection but we know
to today that this system of
tissue regeneration remains
blocked in a situation of
chronic inflammation and because
block at that time because the
cells produce a whole series of
proteins that make these cells
mother do not reach the tissues and not
can repair them is so that what
for example understand that the snuff
Stress and sugar cholesterol
they all act, you know, they act
deteriorating are inflaming our
arteries chronically and that explains
that cardiovascular diseases
until today we do not finish them
understand and it ‘s chronic inflammation
blocks the regeneration system of
our organism and therefore it is a
illness that to this day for now
it has no cure but there we are
US
animated by paco vidal we started a
I’m really studying the treatment that
we do is very simple surprise for your
simplicity and what we do is take out the
bone marrow
there you are seeing it in images to take out
the bone marrow usually
we take out of the tibia because it’s much more
accessible
we take it out under local anesthesia
once removed in conditions of
maximum sterility within a
operating room with a flow chamber
laminate what we do what he does for
take care is to select from all this
bone marrow mesenchymal cells
which are the cells that we
we need to be able to repair the glasses
that are damaged
what are we going to do once
processed in vitro
what we do is inject the form
strategic at the level of the fabric that
we want to repair and in this way we have
could treat patients like this one that
it was about a 50 year old boy who
he had gone through two hospitals and
they had said he had all the
clogged knee arteries down
and that it was impossible to treat what had
so much pain in both hospitals will
they said that the only alternative
therapeutic was sadly the
amputation came to us via web and
agreed to be treated to be treated and
what we did was what is explained
before a week
this boy who took daily
morphine began to lower the dose was a
dose of your treatment until
the pain disappeared between a week and
fifteen days in a short time as you can
see in the photo of that really celebrated
finger and could keep his leg
these good results in the field of
the critical stevia that were not always
good not all patients by
misfortune has preserved retained their
limb and we are really conscious
that this treatment is in their
beginnings and there is a lot of work to do
but if these results encouraged us to
try this way of trying
also stupid to treat lymphedema
chronic
what is this about chronic lymphoedema
it is a disease caused by evil
operation of some very
little ones that are called lymphatics that
he has to be the ones in charge of draining
the liquid and the proteins that are
at the tissue level and that if
accumulate they can come up with what
who see in the photo that it is a case of
elephantiasis are these patients
they really do not have any alternative
therapeutic except compressive therapy
and the lymphatic drainages and really
what we are seeing today are
very hopeful results but
we really are very aware that
all this is in what I am
explaining is in its infancy and
we really have to work on what
it’s called a clinical trial because
there is a great need to have data for
to be able to interpret them and a bit to
deepen also in knowledge
of these stem cells but not only
you have to know the cells better
you also have to investigate in
biomaterials these biomaterials are
those who are going to allow us to build
matrices that we are going to fill in
cells and we will be able to manufacture by
meniscus example to be able to treat the
knee osteoarthritis lumbar hernias and
in the future probably organs
and not only that we have to know better
all those molecules that intervene in
chronic inflammation to be able
improve or unblock this process and
stimulate in some way the
regeneration scale to the
spontaneous tissue regeneration of
organism and we also have to improve
the clinical application is important
all this is important to be aware
that we are in the beginning of this
ica therapist and good the knowledge of
the stem cells has led us
also in a collateral way to know
better the immune system and how to
I was talking about the system at the beginning
immune is important because a
deregulation is what ends
producing the chronic inflammation of
low grade that spoke to them at the beginning
which is the cause of the blockage of
spontaneous regeneration of our
tissues is beginning to talk about
immunotherapy that is that then the
extraction of our defenses the
lymphocytes and the way injection
also strategic in vaccine form
probably in the very near future
will begin to treat many
diseases in this way and between them
cancer
you realize the greatness of everything
this of what it is of what I am
talking is possible that we are
really seeing the light at the end of
tunnel
yes I read a few not only that
really so you can see a little bit what
represent the stem cells what changes
I think they changed everything we are
in front of a revolution as it was
in your day internet and that will end
imposing and that will change everything up
medical praxis will change the way that
we understand doctors today the
medicine and probably will return us
our humanism that we have lost in
the path of technification and not
only that
I read a few days ago in a newspaper
what did he do to be a researcher of
Spanish origin he receives in california
has managed to show in mice that it is
possible to stop aging and not
it is only possible to stop what is possible
reverse it
so why not in the very future
next
humanity will be able to solve one of its
great enigmas or chimeras is possible the
eternal life
thanks more
”
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