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Antibiotic Misuse: Crisis of Today, Failure of Tomorrow | Esteban Silva | TEDxColegioBolivar


[Music]

[Music] [Applause]

[Applause]

[Applause] the last time I decided I was martyr

the last time I decided I was martyr

the last time I decided I was martyr than my doctor and thus prescribed

than my doctor and thus prescribed

than my doctor and thus prescribed myself an antibiotic treatment I ended

myself an antibiotic treatment I ended

myself an antibiotic treatment I ended up on a hospital bed with a terrible

up on a hospital bed with a terrible

up on a hospital bed with a terrible headache and uncontrollable stomachache

headache and uncontrollable stomachache

headache and uncontrollable stomachache and an intravenous drip on my forearm

and an intravenous drip on my forearm

and an intravenous drip on my forearm you idiot

you idiot

you idiot my mother said you practically destroyed

my mother said you practically destroyed

my mother said you practically destroyed all of your necessary life enabling

all of your necessary life enabling

all of your necessary life enabling bacteria as you can guess this

bacteria as you can guess this

bacteria as you can guess this observation was not unique to my mother

observation was not unique to my mother

observation was not unique to my mother and though inadvertently she summarized

and though inadvertently she summarized

and though inadvertently she summarized the two most important features of

the two most important features of

the two most important features of antibiotic overuse first it’s red

antibiotic overuse first it’s red

antibiotic overuse first it’s red dreadful comfort consequences for your

dreadful comfort consequences for your

dreadful comfort consequences for your health and second the fact that it is a

health and second the fact that it is a

health and second the fact that it is a social phenomenon antibiotics

social phenomenon antibiotics

social phenomenon antibiotics revolutionize medicine with their

revolutionize medicine with their

revolutionize medicine with their ability to radical pernicious bacteria

ability to radical pernicious bacteria

ability to radical pernicious bacteria from one’s body and plants cure

from one’s body and plants cure

from one’s body and plants cure infections

infections

infections nevertheless the misuse or overuse of

nevertheless the misuse or overuse of

nevertheless the misuse or overuse of these medications can lead to diseases

these medications can lead to diseases

these medications can lead to diseases such as the one described above or to

such as the one described above or to

such as the one described above or to the formation of superbugs that can

the formation of superbugs that can

the formation of superbugs that can withstand any antibiotic treatment

withstand any antibiotic treatment

withstand any antibiotic treatment apparently the solution to this issue is

apparently the solution to this issue is

apparently the solution to this issue is simple stop consuming antibiotics yet

simple stop consuming antibiotics yet

simple stop consuming antibiotics yet the lack of regulation and the social

the lack of regulation and the social

the lack of regulation and the social normalization of antibiotic use made a

normalization of antibiotic use made a

normalization of antibiotic use made a consumption of this medicine extensive I

consumption of this medicine extensive I

consumption of this medicine extensive I may eventually lead us to a miserable

may eventually lead us to a miserable

may eventually lead us to a miserable pre-antibiotic era if a country has a

pre-antibiotic era if a country has a

pre-antibiotic era if a country has a sufficient supply of antibiotics then it

sufficient supply of antibiotics then it

sufficient supply of antibiotics then it is probably struggling with the misuse

is probably struggling with the misuse

is probably struggling with the misuse of these drugs or has a set of laws that

of these drugs or has a set of laws that

of these drugs or has a set of laws that attempt to regulate their overuse these

attempt to regulate their overuse these

attempt to regulate their overuse these laws are often in existent or variant

laws are often in existent or variant

laws are often in existent or variant agree intrusiveness and quantity but a

agree intrusiveness and quantity but a

agree intrusiveness and quantity but a failure of Nations when it comes to

failure of Nations when it comes to

failure of Nations when it comes to limiting this behavior is a worldwide

limiting this behavior is a worldwide

limiting this behavior is a worldwide phenomenon for instance according to

phenomenon for instance according to

phenomenon for instance according to NCBI expert Levin Tola from 2000 to 2010

NCBI expert Levin Tola from 2000 to 2010

NCBI expert Levin Tola from 2000 to 2010 the world consumption of antibiotics

the world consumption of antibiotics

the world consumption of antibiotics increased by 35% certainly the support

increased by 35% certainly the support

increased by 35% certainly the support rent entails that countries around the

rent entails that countries around the

rent entails that countries around the world are not efficiently limiting the

world are not efficiently limiting the

world are not efficiently limiting the spread prescription and overuse of these

spread prescription and overuse of these

spread prescription and overuse of these medications

medications

medications however surprisingly 76% of this 35%

however surprisingly 76% of this 35%

however surprisingly 76% of this 35% increase can be attributed to five

increase can be attributed to five

increase can be attributed to five countries in particular Brazil Russia

countries in particular Brazil Russia

countries in particular Brazil Russia India China and South Africa which

India China and South Africa which

India China and South Africa which coincidentally also fulfilled the two

coincidentally also fulfilled the two

coincidentally also fulfilled the two requirements for a substantive overuse

requirements for a substantive overuse

requirements for a substantive overuse of antibiotics as of instance a

of antibiotics as of instance a

of antibiotics as of instance a sufficient supply and the

sufficient supply and the

sufficient supply and the over-the-counter beta of these drugs

over-the-counter beta of these drugs

over-the-counter beta of these drugs although this trend can be attributed to

although this trend can be attributed to

although this trend can be attributed to an improvement in healthcare access this

an improvement in healthcare access this

an improvement in healthcare access this explanation is not enough to account for

explanation is not enough to account for

explanation is not enough to account for this huge increment in simpler terms

this huge increment in simpler terms

this huge increment in simpler terms antibiotic misuse is more commonly

antibiotic misuse is more commonly

antibiotic misuse is more commonly associated with country to have flexible

associated with country to have flexible

associated with country to have flexible regulations for the purchase of this

regulations for the purchase of this

regulations for the purchase of this medicine in essence tackle the causation

medicine in essence tackle the causation

medicine in essence tackle the causation is straightforward the lack of

is straightforward the lack of

is straightforward the lack of boundaries in an area where limitations

boundaries in an area where limitations

boundaries in an area where limitations might be same disincentivize undesirable

might be same disincentivize undesirable

might be same disincentivize undesirable conducts encourages or facilitates the

conducts encourages or facilitates the

conducts encourages or facilitates the incorrect prescription of antibiotics

incorrect prescription of antibiotics

incorrect prescription of antibiotics the constant use of these drugs and the

the constant use of these drugs and the

the constant use of these drugs and the permissiveness of experts for example

permissiveness of experts for example

permissiveness of experts for example antibiotics are an over-the-counter drug

antibiotics are an over-the-counter drug

antibiotics are an over-the-counter drug in Colombia does the lack of regulation

in Colombia does the lack of regulation

in Colombia does the lack of regulation has the to rising cost for the Colombian

has the to rising cost for the Colombian

has the to rising cost for the Colombian government which currently placed two

government which currently placed two

government which currently placed two hundred and forty two billion dollars in

hundred and forty two billion dollars in

hundred and forty two billion dollars in a type of antibiotic overuse cases for

a type of antibiotic overuse cases for

a type of antibiotic overuse cases for its subsidised citizens for this example

its subsidised citizens for this example

its subsidised citizens for this example it is crucial to note that an increase

it is crucial to note that an increase

it is crucial to note that an increase in subsidized medical costs implies an

in subsidized medical costs implies an

in subsidized medical costs implies an increasing number of antibiotic overuse

increasing number of antibiotic overuse

increasing number of antibiotic overuse cases and therefore subject suggests

cases and therefore subject suggests

cases and therefore subject suggests that minimal regulations lead to the

that minimal regulations lead to the

that minimal regulations lead to the overuse of these medications since laws

overuse of these medications since laws

overuse of these medications since laws are created as a response to

are created as a response to

are created as a response to pre-existing social conditions the

pre-existing social conditions the

pre-existing social conditions the regulations the regulations that limit

regulations the regulations that limit

regulations the regulations that limit the consumption of antibiotics must be

the consumption of antibiotics must be

the consumption of antibiotics must be attempting to offset the social factors

attempting to offset the social factors

attempting to offset the social factors that cause this issue then what are the

that cause this issue then what are the

that cause this issue then what are the social factors that lead to this

social factors that lead to this

social factors that lead to this phenomenon negative externalities

phenomenon negative externalities

phenomenon negative externalities doctor-patient relationships and pig

doctor-patient relationships and pig

doctor-patient relationships and pig neurons are the three risk factors that

neurons are the three risk factors that

neurons are the three risk factors that are normalizing and proliferating the

are normalizing and proliferating the

are normalizing and proliferating the use of antibiotics

use of antibiotics

use of antibiotics an externality is a consequence that is

an externality is a consequence that is

an externality is a consequence that is produced by someone who does not receive

produced by someone who does not receive

produced by someone who does not receive that direct impacts of the action in

that direct impacts of the action in

that direct impacts of the action in effect the reconstruction antibiotics

effect the reconstruction antibiotics

effect the reconstruction antibiotics can be considered an externality which

can be considered an externality which

can be considered an externality which doctors and patients are willing to

doctors and patients are willing to

doctors and patients are willing to undertake because as the McDonald norms

undertake because as the McDonald norms

undertake because as the McDonald norms group points out the action an

group points out the action an

group points out the action an undesirable consequence are so widely

undesirable consequence are so widely

undesirable consequence are so widely separated in time that the relationship

separated in time that the relationship

separated in time that the relationship is unrecognized or not knowledged

is unrecognized or not knowledged

is unrecognized or not knowledged nonetheless this recklessness and

nonetheless this recklessness and

nonetheless this recklessness and carelessness that allows individuals to

carelessness that allows individuals to

carelessness that allows individuals to undermine the health of the overall

undermine the health of the overall

undermine the health of the overall society has a major route in a less

society has a major route in a less

society has a major route in a less economic concept ignorant or lack of

economic concept ignorant or lack of

economic concept ignorant or lack of awareness the question is how can

awareness the question is how can

awareness the question is how can individuals be expected to suppress

individuals be expected to suppress

individuals be expected to suppress their self-interest when they ignore the

their self-interest when they ignore the

their self-interest when they ignore the basic implications of the matter in

basic implications of the matter in

basic implications of the matter in other words if someone does not know

other words if someone does not know

other words if someone does not know that the misuse of antibiotics may lead

that the misuse of antibiotics may lead

that the misuse of antibiotics may lead to superbugs or harmful disease then she

to superbugs or harmful disease then she

to superbugs or harmful disease then she will properly guide her decision on her

will properly guide her decision on her

will properly guide her decision on her self-interest and the almost folkloric

self-interest and the almost folkloric

self-interest and the almost folkloric belief that antibiotics can cure

belief that antibiotics can cure

belief that antibiotics can cure anything now for antibiotic in frantic

anything now for antibiotic in frantic

anything now for antibiotic in frantic work ignorance to be a trend a

work ignorance to be a trend a

work ignorance to be a trend a significant portion of the population

significant portion of the population

significant portion of the population has to suffer it according to a survey

has to suffer it according to a survey

has to suffer it according to a survey we conducted with the students of polio

we conducted with the students of polio

we conducted with the students of polio volleyer

volleyer

volleyer 55% of the people surveyed did not know

55% of the people surveyed did not know

55% of the people surveyed did not know the possible consequences of antibiotic

the possible consequences of antibiotic

the possible consequences of antibiotic overuse despite the small sample size

overuse despite the small sample size

overuse despite the small sample size and the probable measuring errors this

and the probable measuring errors this

and the probable measuring errors this number is still relevant enough to

number is still relevant enough to

number is still relevant enough to suggest that there is a relative

suggest that there is a relative

suggest that there is a relative ignorance in the population with regards

ignorance in the population with regards

ignorance in the population with regards to the effects of this phenomenon hence

to the effects of this phenomenon hence

to the effects of this phenomenon hence the ignorance evinced by the present

the ignorance evinced by the present

the ignorance evinced by the present American cure anything can be classified

American cure anything can be classified

American cure anything can be classified as a possible cause for the

as a possible cause for the

as a possible cause for the normalization of antibiotic

normalization of antibiotic

normalization of antibiotic overconsumption

overconsumption

overconsumption ultimately the incentive scheme

ultimately the incentive scheme

ultimately the incentive scheme involving the doctor-patient

involving the doctor-patient

involving the doctor-patient relationship is creating a situation in

relationship is creating a situation in

relationship is creating a situation in which inappropriate prescribing has

which inappropriate prescribing has

which inappropriate prescribing has become the norm in short the

become the norm in short the

become the norm in short the doctor-patient relationship because it’s

doctor-patient relationship because it’s

doctor-patient relationship because it’s of a trade-off where the doctor is if

of a trade-off where the doctor is if

of a trade-off where the doctor is if recognition and the patient perceives he

recognition and the patient perceives he

recognition and the patient perceives he was adequately treated

was adequately treated

was adequately treated this trade-off encourages antibiotic

this trade-off encourages antibiotic

this trade-off encourages antibiotic prescription because we disciplined the

prescription because we disciplined the

prescription because we disciplined the patient concludes who concludes his his

patient concludes who concludes his his

patient concludes who concludes his his sickness has been acknowledged and is

sickness has been acknowledged and is

sickness has been acknowledged and is being treated and does the doctor

being treated and does the doctor

being treated and does the doctor ensures that his work is appreciated

ensures that his work is appreciated

ensures that his work is appreciated sadly these social norms that often

sadly these social norms that often

sadly these social norms that often yield favorable relations are creating

yield favorable relations are creating

yield favorable relations are creating in this context a detrimental precedent

in this context a detrimental precedent

in this context a detrimental precedent that normalizes antibiotic consumption

that normalizes antibiotic consumption

that normalizes antibiotic consumption by portraying it as routine like in some

by portraying it as routine like in some

by portraying it as routine like in some although these societal factors converge

although these societal factors converge

although these societal factors converge into one ever growing snowball of

into one ever growing snowball of

into one ever growing snowball of antibiotic overuse which in turn

antibiotic overuse which in turn

antibiotic overuse which in turn produces drug-resistant bacteria at a

produces drug-resistant bacteria at a

produces drug-resistant bacteria at a faster rate since ordinary bacteria

faster rate since ordinary bacteria

faster rate since ordinary bacteria season there are ordinary antibiotics

season there are ordinary antibiotics

season there are ordinary antibiotics eliminate ordinary bacteria but not

eliminate ordinary bacteria but not

eliminate ordinary bacteria but not super pac’s the overuse of this

super pac’s the overuse of this

super pac’s the overuse of this medication enables the latter to survive

medication enables the latter to survive

medication enables the latter to survive and pass it’s drug resistant genes to

and pass it’s drug resistant genes to

and pass it’s drug resistant genes to its offspring and fourth permitting them

its offspring and fourth permitting them

its offspring and fourth permitting them to multiply the kind altum Utley

to multiply the kind altum Utley

to multiply the kind altum Utley unfortunately this natural selection

unfortunately this natural selection

unfortunately this natural selection process is exacerbated as the number of

process is exacerbated as the number of

process is exacerbated as the number of reckless consumers increases likewise it

reckless consumers increases likewise it

reckless consumers increases likewise it is important to understand that

is important to understand that

is important to understand that resistance is also developed naturally

resistance is also developed naturally

resistance is also developed naturally in fact microbes effortlessly evolve and

in fact microbes effortlessly evolve and

in fact microbes effortlessly evolve and adapt to their environment the total

adapt to their environment the total

adapt to their environment the total total due to their genetic plasticity

total due to their genetic plasticity

total due to their genetic plasticity and rapid replication it takes factory a

and rapid replication it takes factory a

and rapid replication it takes factory a 20 to 30 minutes to replicate this

20 to 30 minutes to replicate this

20 to 30 minutes to replicate this ability makes makes it easy for microbes

ability makes makes it easy for microbes

ability makes makes it easy for microbes to whip off and become each time more

to whip off and become each time more

to whip off and become each time more resistant moreover when scientists leave

resistant moreover when scientists leave

resistant moreover when scientists leave intolerance antibiotic development is no

intolerance antibiotic development is no

intolerance antibiotic development is no longer considered to be an economically

longer considered to be an economically

longer considered to be an economically wise investment for the pharmaceutical

wise investment for the pharmaceutical

wise investment for the pharmaceutical industry he is simply listing a fact

industry he is simply listing a fact

industry he is simply listing a fact that the Spiritist companies from

that the Spiritist companies from

that the Spiritist companies from creating new more effective antibiotics

creating new more effective antibiotics

creating new more effective antibiotics the data from the Center for Disease

the data from the Center for Disease

the data from the Center for Disease Control and Prevention demonstrates that

Control and Prevention demonstrates that

Control and Prevention demonstrates that the number of antibiotics created and

the number of antibiotics created and

the number of antibiotics created and approved in the US has decreased from 33

approved in the US has decreased from 33

approved in the US has decreased from 33 approvals between 1985 and 2000 to just

approvals between 1985 and 2000 to just

approvals between 1985 and 2000 to just 13 bit approvals between 2000 and 2014

13 bit approvals between 2000 and 2014

13 bit approvals between 2000 and 2014 therefore the increasing misuse of

therefore the increasing misuse of

therefore the increasing misuse of antibiotics and the decreasing phase

antibiotics and the decreasing phase

antibiotics and the decreasing phase antibiotics that cannot set a resistance

antibiotics that cannot set a resistance

antibiotics that cannot set a resistance crisis are creating a perfect storm

crisis are creating a perfect storm

crisis are creating a perfect storm which dr. BOTS bulwark asserts can mean

which dr. BOTS bulwark asserts can mean

which dr. BOTS bulwark asserts can mean a literal return to the priyanka bi

a literal return to the priyanka bi

a literal return to the priyanka bi priyanka very Kara for many types of

priyanka very Kara for many types of

priyanka very Kara for many types of infections although some experts may be

infections although some experts may be

infections although some experts may be right

right

right when criticizing this conclusion as an

when criticizing this conclusion as an

when criticizing this conclusion as an unrealistic doomsday scenario they

unrealistic doomsday scenario they

unrealistic doomsday scenario they cannot deny that they’re resistant

cannot deny that they’re resistant

cannot deny that they’re resistant prices cannot offsetting implications

prices cannot offsetting implications

prices cannot offsetting implications for modern medicine if the social and

for modern medicine if the social and

for modern medicine if the social and pharmaceutical response to this issue

pharmaceutical response to this issue

pharmaceutical response to this issue continues to be postponed then in a few

continues to be postponed then in a few

continues to be postponed then in a few years the medical field might face an

years the medical field might face an

years the medical field might face an ever growing number of cases that cannot

ever growing number of cases that cannot

ever growing number of cases that cannot be treated with a current spectrum of

be treated with a current spectrum of

be treated with a current spectrum of antibiotics or might have to deal with a

antibiotics or might have to deal with a

antibiotics or might have to deal with a cyclical multiplier effect in which the

cyclical multiplier effect in which the

cyclical multiplier effect in which the use of antibiotics cannot be halted and

use of antibiotics cannot be halted and

use of antibiotics cannot be halted and does superbugs continued to evolve in

does superbugs continued to evolve in

does superbugs continued to evolve in conclusion the anecdote from the

conclusion the anecdote from the

conclusion the anecdote from the beginning is not attempt to cosmetically

beginning is not attempt to cosmetically

beginning is not attempt to cosmetically captured the attention of the reader but

captured the attention of the reader but

captured the attention of the reader but a true example where society where

a true example where society where

a true example where society where societal forces and the lean issue of

societal forces and the lean issue of

societal forces and the lean issue of the law converge to express themselves

the law converge to express themselves

the law converge to express themselves as the oricon structure of antibiotics

as the oricon structure of antibiotics

as the oricon structure of antibiotics this example is the equivalent of one

this example is the equivalent of one

this example is the equivalent of one drop of water in the world’s oceans

drop of water in the world’s oceans

drop of water in the world’s oceans since there are millions and millions of

since there are millions and millions of

since there are millions and millions of similar cases which combine to produce

similar cases which combine to produce

similar cases which combine to produce drug-resistant bacteria that threaten

drug-resistant bacteria that threaten

drug-resistant bacteria that threaten our return to a pre-antibiotic era the

our return to a pre-antibiotic era the

our return to a pre-antibiotic era the fact a scientist considered a previous

fact a scientist considered a previous

fact a scientist considered a previous sentence to be a possibility should be

sentence to be a possibility should be

sentence to be a possibility should be enough to instigate a response that

enough to instigate a response that

enough to instigate a response that attempts to counter antibiotic

attempts to counter antibiotic

attempts to counter antibiotic resistance the reaction has been ignored

resistance the reaction has been ignored

resistance the reaction has been ignored the solution to this issue should be a

the solution to this issue should be a

the solution to this issue should be a burden of the collective not just an

burden of the collective not just an

burden of the collective not just an obligation of scientists and ladies

obligation of scientists and ladies

obligation of scientists and ladies ladies Labor’s the solution to this

ladies Labor’s the solution to this

ladies Labor’s the solution to this issue lies in the hands of every patient

issue lies in the hands of every patient

issue lies in the hands of every patient and doctor who breaks the cycle of

and doctor who breaks the cycle of

and doctor who breaks the cycle of overconsumption the solution of this

overconsumption the solution of this

overconsumption the solution of this issue must be based on encouraging

issue must be based on encouraging

issue must be based on encouraging self-control and awareness the solution

self-control and awareness the solution

self-control and awareness the solution of this issue is conceivable and must be

of this issue is conceivable and must be

of this issue is conceivable and must be certain motion right now thank

certain motion right now thank

certain motion right now thank [Applause]

”

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