my work focuses on finding individual memories in the brain and actually
memories in the brain and actually
memories in the brain and actually turning them on or off we had a series
turning them on or off we had a series
turning them on or off we had a series of projects where we started off by
of projects where we started off by
of projects where we started off by asking really simply can we go in and
asking really simply can we go in and
asking really simply can we go in and can we just find a memory in the brain
can we just find a memory in the brain
can we just find a memory in the brain can we isolate a memory in the brain
can we isolate a memory in the brain
can we isolate a memory in the brain every memory is realized at the level of
every memory is realized at the level of
every memory is realized at the level of individual brain cells we have to find
individual brain cells we have to find
individual brain cells we have to find the brain cells that were holding on to
the brain cells that were holding on to
the brain cells that were holding on to one particular memory once we were able
one particular memory once we were able
one particular memory once we were able to do that we asked can we actually
to do that we asked can we actually
to do that we asked can we actually modulate that memory could we activate
modulate that memory could we activate
modulate that memory could we activate it could be inactivated again can we
it could be inactivated again can we
it could be inactivated again can we change the contents of it so to do that
change the contents of it so to do that
change the contents of it so to do that we had to go in and we have to
we had to go in and we have to
we had to go in and we have to genetically hijack those brain cells and
genetically hijack those brain cells and
genetically hijack those brain cells and trick those brain cells to respond to
trick those brain cells to respond to
trick those brain cells to respond to pulses of light we did that by
pulses of light we did that by
pulses of light we did that by artificially installing this light
artificially installing this light
artificially installing this light sensitive switch so that now we know
sensitive switch so that now we know
sensitive switch so that now we know which brain cells are involved in
which brain cells are involved in
which brain cells are involved in holding on to a memory and we also now
holding on to a memory and we also now
holding on to a memory and we also now have these cells that respond to pulses
have these cells that respond to pulses
have these cells that respond to pulses of light so we can literally go into the
of light so we can literally go into the
of light so we can literally go into the brain shoot lasers into the brain and
brain shoot lasers into the brain and
brain shoot lasers into the brain and either activate those brain cells and
either activate those brain cells and
either activate those brain cells and thereby activate a memory or inactivate
thereby activate a memory or inactivate
thereby activate a memory or inactivate those brain cells and thereby
those brain cells and thereby
those brain cells and thereby inactivated memory we’re able to go into
inactivated memory we’re able to go into
inactivated memory we’re able to go into the brain and dial up let’s say the
the brain and dial up let’s say the
the brain and dial up let’s say the emotional oof associated with a
emotional oof associated with a
emotional oof associated with a particular memory or dial down the
particular memory or dial down the
particular memory or dial down the emotional Uma associated with the memory
emotional Uma associated with the memory
emotional Uma associated with the memory more recently actually we’ve been able
more recently actually we’ve been able
more recently actually we’ve been able to go into the brain and isolate
to go into the brain and isolate
to go into the brain and isolate individual positive memories now this is
individual positive memories now this is
individual positive memories now this is powerful because we can go and we can
powerful because we can go and we can
powerful because we can go and we can isolate and reactivate positive memories
isolate and reactivate positive memories
isolate and reactivate positive memories and one figure out what does this tell
and one figure out what does this tell
and one figure out what does this tell us about the brain right what’s
us about the brain right what’s
us about the brain right what’s happening in the brain when we do this
happening in the brain when we do this
happening in the brain when we do this but in my opinion just as importantly we
but in my opinion just as importantly we
but in my opinion just as importantly we can go and use these artificially
can go and use these artificially
can go and use these artificially activated positive memories you can
activated positive memories you can
activated positive memories you can think of them as sort of weapons now
think of them as sort of weapons now
think of them as sort of weapons now against certain psychiatric disorders to
against certain psychiatric disorders to
against certain psychiatric disorders to the extent that we can model those and
the extent that we can model those and
the extent that we can model those and animals so imagine that we can actually
animals so imagine that we can actually
animals so imagine that we can actually go in and we can generate animal models
go in and we can generate animal models
go in and we can generate animal models of things like anxiety depression PTSD
of things like anxiety depression PTSD
of things like anxiety depression PTSD and so on and actually harness the
and so on and actually harness the
and so on and actually harness the brain’s powers and force it to jumpstart
brain’s powers and force it to jumpstart
brain’s powers and force it to jumpstart this process of recollection of a
this process of recollection of a
this process of recollection of a positive memory and force it to suppress
positive memory and force it to suppress
positive memory and force it to suppress some of these symptoms associated with a
some of these symptoms associated with a
some of these symptoms associated with a variety of mood disorders my work is
variety of mood disorders my work is
variety of mood disorders my work is addicting you look at something under
addicting you look at something under
addicting you look at something under the microscope or your mouse is doing
the microscope or your mouse is doing
the microscope or your mouse is doing something and if it’s a true discovery
something and if it’s a true discovery
something and if it’s a true discovery you’re the only person in the world
you’re the only person in the world
you’re the only person in the world that’s looking at that one thing at that
that’s looking at that one thing at that
that’s looking at that one thing at that moment you’re at that edge of the known
moment you’re at that edge of the known
moment you’re at that edge of the known and the unknown and when you make a tiny
and the unknown and when you make a tiny
and the unknown and when you make a tiny even incremental advance into the
even incremental advance into the
even incremental advance into the unknown that’s like a drug like that’s
unknown that’s like a drug like that’s
unknown that’s like a drug like that’s whole other thing
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