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Could Tweaking Our Memories Help Us Feel Better? | Nat Geo Live


The work that I’ve been doing at MIT

focuses on finding

individual memories in the brain

and then trying to actually tinker with those memories.

Can we turn them on, can we turn them off

can we change the contents of those memories?

Ethical stuff aside, you can imagine the implications

for things like actually being able to

activate memories in Alzheimer’s, for example.

Or using memories to combat certain symptoms

associated with psychiatric disorders.

The main question that we started off

tackling was, can we go in,

can we find the brain cells

that are active during a particular memory

and again, can we actually modulate those brain cells.

So, what we would do is, uh, we would go in

we would find these brain cells that

we think are holding on to a particular memory

and we would actually artificially install

a light-sensitive switch in those brain cells.

So, that means that we can actually take an optic fiber,

do some careful brain surgery

and actually shoot lasers into the brain

and reactivate these brain cells or inactivate these brain cells

that we think are housing a particular memory.

You don’t have to imagine any more

the possibility of bringing back a memory that

was once thought to be lost, in a patient with Alzheimer’s.

Or imagine going in and turning the dial down

on the emotional gut-wrenching “I hate my life” feeling of…

not a breakup but something more seriously, something like PTSD.

Imagine being able to turn the dial down

on those negative emotions.

Or being able to jump start particular moods

when your mood is really low

or even under depression, uh, in a depressed state.

So, those are the things that we don’t have to imagine any more.

Those are the things that we are on the cusp of

actually being able to do

with, I think, powerful therapeutic value.

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