you very much for coming today so let me start with asking you a question when
start with asking you a question when
start with asking you a question when you look around in the seats here what
you look around in the seats here what
you look around in the seats here what do you see probably people and maybe
do you see probably people and maybe
do you see probably people and maybe it’s because my background in computer
it’s because my background in computer
it’s because my background in computer science and and then becoming a
science and and then becoming a
science and and then becoming a molecular biologist what I see are
molecular biologist what I see are
molecular biologist what I see are trillions of cells grouped together
trillions of cells grouped together
trillions of cells grouped together collaborating to form human beings and
collaborating to form human beings and
collaborating to form human beings and they they are actually little organic
they they are actually little organic
they they are actually little organic computers that every cell is just an
computers that every cell is just an
computers that every cell is just an organic computer that runs off of
organic computer that runs off of
organic computer that runs off of software DNA
software DNA
software DNA and that they they network together in
and that they they network together in
and that they they network together in an incredibly sophisticated way even
an incredibly sophisticated way even
an incredibly sophisticated way even more than sophisticated than computers
more than sophisticated than computers
more than sophisticated than computers in order to give you all of your
in order to give you all of your
in order to give you all of your physical capabilities but even your
physical capabilities but even your
physical capabilities but even your thoughts your emotions your memories and
thoughts your emotions your memories and
thoughts your emotions your memories and probably even your consciousness so it’s
probably even your consciousness so it’s
probably even your consciousness so it’s a remarkably complex computer but it’s a
a remarkably complex computer but it’s a
a remarkably complex computer but it’s a computer nonetheless and the parallels
computer nonetheless and the parallels
computer nonetheless and the parallels are so compelling that I could speak for
are so compelling that I could speak for
are so compelling that I could speak for that you know for a day so I won’t get
that you know for a day so I won’t get
that you know for a day so I won’t get into it in a lot of depth but I will
into it in a lot of depth but I will
into it in a lot of depth but I will want to draw some parallels for you to
want to draw some parallels for you to
want to draw some parallels for you to help you to understand a revolution that
help you to understand a revolution that
help you to understand a revolution that is coming in healthcare that is going to
is coming in healthcare that is going to
is coming in healthcare that is going to yield miracle cures to things that were
yield miracle cures to things that were
yield miracle cures to things that were formerly untreatable or incurable and
formerly untreatable or incurable and
formerly untreatable or incurable and you know this thing is happening right
you know this thing is happening right
you know this thing is happening right now
now
now it’s accelerating we’re getting a drip
it’s accelerating we’re getting a drip
it’s accelerating we’re getting a drip drip drip of miracle cures already but
drip drip of miracle cures already but
drip drip of miracle cures already but this is going to become a steady stream
this is going to become a steady stream
this is going to become a steady stream and it’s going to become a deluge in the
and it’s going to become a deluge in the
and it’s going to become a deluge in the near future and it’s going to touch us
near future and it’s going to touch us
near future and it’s going to touch us all and it’s extremely exciting and it’s
all and it’s extremely exciting and it’s
all and it’s extremely exciting and it’s an extremely exciting extremely positive
an extremely exciting extremely positive
an extremely exciting extremely positive thing that’s going to happen to society
thing that’s going to happen to society
thing that’s going to happen to society and to us as individuals let’s see I
and to us as individuals let’s see I
and to us as individuals let’s see I gotta figure out which one’s Plus here
gotta figure out which one’s Plus here
gotta figure out which one’s Plus here that one ah there we go
that one ah there we go
that one ah there we go so my talk is basically about
so my talk is basically about
so my talk is basically about reprogramming the human computer so let
reprogramming the human computer so let
reprogramming the human computer so let me talk a little bit about the
me talk a little bit about the
me talk a little bit about the differences between a regular computer
differences between a regular computer
differences between a regular computer and a human computer so a regular
and a human computer so a regular
and a human computer so a regular computer works in base2 or binary or
computer works in base2 or binary or
computer works in base2 or binary or zeros and ones it has two symbols that
zeros and ones it has two symbols that
zeros and ones it has two symbols that essentially make up all the commands for
essentially make up all the commands for
essentially make up all the commands for a computer in your body
a computer in your body
a computer in your body it’s here’s the first thing that’s more
it’s here’s the first thing that’s more
it’s here’s the first thing that’s more sophisticated about it your cells
sophisticated about it your cells
sophisticated about it your cells operate in a CTE GeForce
operate in a CTE GeForce
operate in a CTE GeForce cymbals or bass for but they still are
cymbals or bass for but they still are
cymbals or bass for but they still are organized the software the DNA is
organized the software the DNA is
organized the software the DNA is organized into commands and the order of
organized into commands and the order of
organized into commands and the order of that ACTG is what determines what your
that ACTG is what determines what your
that ACTG is what determines what your cells do and these genes determine what
cells do and these genes determine what
cells do and these genes determine what your cells make are they making enzymes
your cells make are they making enzymes
your cells make are they making enzymes proteins things to secrete
proteins things to secrete
proteins things to secrete light-sensitive proteins that turn into
light-sensitive proteins that turn into
light-sensitive proteins that turn into electrical signals that go into your
electrical signals that go into your
electrical signals that go into your brain
brain
brain stomach acid whatever it is it’s all
stomach acid whatever it is it’s all
stomach acid whatever it is it’s all encoded by genes and even though the DNA
encoded by genes and even though the DNA
encoded by genes and even though the DNA is the same in every single one of your
is the same in every single one of your
is the same in every single one of your cells it’s a complete operating system
cells it’s a complete operating system
cells it’s a complete operating system right you know you have a network of
right you know you have a network of
right you know you have a network of computers at your university here we
computers at your university here we
computers at your university here we have one at work not every computer is
have one at work not every computer is
have one at work not every computer is doing the same thing it’s running
doing the same thing it’s running
doing the same thing it’s running different parts of its operating system
different parts of its operating system
different parts of its operating system as necessary and that’s exactly what
as necessary and that’s exactly what
as necessary and that’s exactly what your cells do as well each cell has a
your cells do as well each cell has a
your cells do as well each cell has a essentially a manager is called the
essentially a manager is called the
essentially a manager is called the endogenous promoter that knows which
endogenous promoter that knows which
endogenous promoter that knows which part of your DNA applies to that cell so
part of your DNA applies to that cell so
part of your DNA applies to that cell so that cell can do its job every day in
that cell can do its job every day in
that cell can do its job every day in that collection those trillions of cells
that collection those trillions of cells
that collection those trillions of cells that make you up so you could imagine
that make you up so you could imagine
that make you up so you could imagine you know with this sort of view of human
you know with this sort of view of human
you know with this sort of view of human beings if we could change that operating
beings if we could change that operating
beings if we could change that operating system if we could modify that operating
system if we could modify that operating
system if we could modify that operating system if we could update that operating
system if we could update that operating
system if we could update that operating system we could make you work better and
system we could make you work better and
system we could make you work better and you would be right you know what what
you would be right you know what what
you would be right you know what what could we do if we could go ahead and
could we do if we could go ahead and
could we do if we could go ahead and update that operating system and get rid
update that operating system and get rid
update that operating system and get rid of the defects or even improve the the
of the defects or even improve the the
of the defects or even improve the the way that it works right now but I think
way that it works right now but I think
way that it works right now but I think you know let’s focus on the defects
you know let’s focus on the defects
you know let’s focus on the defects first well the question might be more
first well the question might be more
first well the question might be more what can’t we do right we’re limited
what can’t we do right we’re limited
what can’t we do right we’re limited right now by our understanding of how
right now by our understanding of how
right now by our understanding of how genes work even though we sequenced the
genes work even though we sequenced the
genes work even though we sequenced the human genome all’s it did was give us
human genome all’s it did was give us
human genome all’s it did was give us the order of that ACTG but it didn’t
the order of that ACTG but it didn’t
the order of that ACTG but it didn’t tell us what every single one of those
tell us what every single one of those
tell us what every single one of those genes did and it also didn’t tell us how
genes did and it also didn’t tell us how
genes did and it also didn’t tell us how they interact but what it did was it it
they interact but what it did was it it
they interact but what it did was it it unlocked a whole bunch of research that
unlocked a whole bunch of research that
unlocked a whole bunch of research that is yielding exactly that information the
is yielding exactly that information the
is yielding exactly that information the driver genes behind all different types
driver genes behind all different types
driver genes behind all different types of diseases and once we understand how
of diseases and once we understand how
of diseases and once we understand how those genes interact we can couple that
those genes interact we can couple that
those genes interact we can couple that together with our ability to change that
together with our ability to change that
together with our ability to change that code in order to improve the operation
code in order to improve the operation
code in order to improve the operation and in order to mitigate the
and in order to mitigate the
and in order to mitigate the drivers of diseases and to essentially
drivers of diseases and to essentially
drivers of diseases and to essentially cure or treat
cure or treat
cure or treat diseases in ways that we never could
diseases in ways that we never could
diseases in ways that we never could before this is way more powerful than
before this is way more powerful than
before this is way more powerful than other types of drug development
other types of drug development
other types of drug development modalities and it really boils down to
modalities and it really boils down to
modalities and it really boils down to something called the viral vector so the
something called the viral vector so the
something called the viral vector so the viral vector is quite simply taking a
viral vector is quite simply taking a
viral vector is quite simply taking a deadly virus or a possibly a deadly
deadly virus or a possibly a deadly
deadly virus or a possibly a deadly virus cracking it open and scooping out
virus cracking it open and scooping out
virus cracking it open and scooping out the viral DNA those little snippets of
the viral DNA those little snippets of
the viral DNA those little snippets of code that take over your system and do
code that take over your system and do
code that take over your system and do something bad with it we can throw that
something bad with it we can throw that
something bad with it we can throw that away and we can put update code in its
away and we can put update code in its
away and we can put update code in its instead so instead of using you know
instead so instead of using you know
instead so instead of using you know that carrying capacity these viruses
that carrying capacity these viruses
that carrying capacity these viruses have been doing this for millions of
have been doing this for millions of
have been doing this for millions of years in your body or in in the human’s
years in your body or in in the human’s
years in your body or in in the human’s bodies you know they’ve been essentially
bodies you know they’ve been essentially
bodies you know they’ve been essentially hijacking your cells by dropping a
hijacking your cells by dropping a
hijacking your cells by dropping a little snippets of code in there and
little snippets of code in there and
little snippets of code in there and doing what well that’s sort of the same
doing what well that’s sort of the same
doing what well that’s sort of the same thing that viruses do on your computer
thing that viruses do on your computer
thing that viruses do on your computer they take over your computer for some
they take over your computer for some
they take over your computer for some malevolent purpose something that
malevolent purpose something that
malevolent purpose something that doesn’t serve you as the host right you
doesn’t serve you as the host right you
doesn’t serve you as the host right you as the human being usually most viruses
as the human being usually most viruses
as the human being usually most viruses all they do is they carry instructions
all they do is they carry instructions
all they do is they carry instructions to replicate themselves cold viruses
to replicate themselves cold viruses
to replicate themselves cold viruses that’s pretty much all they are they
that’s pretty much all they are they
that’s pretty much all they are they hijack the system they’re so effective
hijack the system they’re so effective
hijack the system they’re so effective that when a cold virus gets into a cell
that when a cold virus gets into a cell
that when a cold virus gets into a cell that cell is a goner for sure it’s a
that cell is a goner for sure it’s a
that cell is a goner for sure it’s a dead cell because they will hijack that
dead cell because they will hijack that
dead cell because they will hijack that cell and they’ll make it use up all of
cell and they’ll make it use up all of
cell and they’ll make it use up all of its energy all of its resources all of
its energy all of its resources all of
its energy all of its resources all of its machinery to just make copies of the
its machinery to just make copies of the
its machinery to just make copies of the cold virus and eventually it’ll run out
cold virus and eventually it’ll run out
cold virus and eventually it’ll run out of materials in the cell just falls
of materials in the cell just falls
of materials in the cell just falls apart and those copies of the virus
apart and those copies of the virus
apart and those copies of the virus escape and what do they do go on to the
escape and what do they do go on to the
escape and what do they do go on to the next cells and don’t worry about that
next cells and don’t worry about that
next cells and don’t worry about that you know colds are only deadly if you
you know colds are only deadly if you
you know colds are only deadly if you don’t have an immune system right
don’t have an immune system right
don’t have an immune system right because your immune system is actually
because your immune system is actually
because your immune system is actually even faster it can overtake that cold
even faster it can overtake that cold
even faster it can overtake that cold and it’s not a problem and I’m going to
and it’s not a problem and I’m going to
and it’s not a problem and I’m going to tell you a little bit more about that
tell you a little bit more about that
tell you a little bit more about that when I talk about our HIV functional
when I talk about our HIV functional
when I talk about our HIV functional cure but you know that’s the the idea is
cure but you know that’s the the idea is
cure but you know that’s the the idea is that these viruses have been carrying
that these viruses have been carrying
that these viruses have been carrying out this hijacking for millions of years
out this hijacking for millions of years
out this hijacking for millions of years what scientists have discovered how to
what scientists have discovered how to
what scientists have discovered how to do is to hijack the hijacker right
do is to hijack the hijacker right
do is to hijack the hijacker right viruses and updates on your computer
viruses and updates on your computer
viruses and updates on your computer arrived pretty much the same way right
arrived pretty much the same way right
arrived pretty much the same way right they usually come in over the internet
they usually come in over the internet
they usually come in over the internet or attached to an email
or attached to an email
or attached to an email or you download them from somewhere
or you download them from somewhere
or you download them from somewhere you’d run them and then you click on
you’d run them and then you click on
you’d run them and then you click on their ok to install and you hope it’s
their ok to install and you hope it’s
their ok to install and you hope it’s from a reputable source like Microsoft
from a reputable source like Microsoft
from a reputable source like Microsoft Apple Adobe or somebody that you could
Apple Adobe or somebody that you could
Apple Adobe or somebody that you could trust but it could be a virus what
trust but it could be a virus what
trust but it could be a virus what you’ve done is you’ve unlocked your
you’ve done is you’ve unlocked your
you’ve done is you’ve unlocked your computer’s DNA to whatever code snippet
computer’s DNA to whatever code snippet
computer’s DNA to whatever code snippet is in there and it’s going to do what
is in there and it’s going to do what
is in there and it’s going to do what it’s going to do so a virus and an
it’s going to do so a virus and an
it’s going to do so a virus and an update really you know sort of
update really you know sort of
update really you know sort of mechanically isn’t any different on your
mechanically isn’t any different on your
mechanically isn’t any different on your computer it’s just its intent is
computer it’s just its intent is
computer it’s just its intent is different well it’s the same thing when
different well it’s the same thing when
different well it’s the same thing when we hijacked the hijacker so we crack
we hijacked the hijacker so we crack
we hijacked the hijacker so we crack open a deadly virus and as a matter of
open a deadly virus and as a matter of
open a deadly virus and as a matter of fact what a GT uses is HIV Wow and we
fact what a GT uses is HIV Wow and we
fact what a GT uses is HIV Wow and we scoop out the DNA from HIV which is the
scoop out the DNA from HIV which is the
scoop out the DNA from HIV which is the AIDS virus and we also scoop out all of
AIDS virus and we also scoop out all of
AIDS virus and we also scoop out all of its capability to replicate because we
its capability to replicate because we
its capability to replicate because we don’t want to create a new virus what we
don’t want to create a new virus what we
don’t want to create a new virus what we want to do is use the delivery
want to do is use the delivery
want to do is use the delivery capabilities of that virus to deliver
capabilities of that virus to deliver
capabilities of that virus to deliver something beneficial to you now on your
something beneficial to you now on your
something beneficial to you now on your computer right some of your software is
computer right some of your software is
computer right some of your software is actually that you download and install
actually that you download and install
actually that you download and install is to protect you from viruses that’s
is to protect you from viruses that’s
is to protect you from viruses that’s right viruses or updates can get rid of
right viruses or updates can get rid of
right viruses or updates can get rid of viruses and that’s exactly what we do
viruses and that’s exactly what we do
viruses and that’s exactly what we do with HIV we can use it to treat viruses
with HIV we can use it to treat viruses
with HIV we can use it to treat viruses we can get it to hunt down viruses in
we can get it to hunt down viruses in
we can get it to hunt down viruses in your body change your DNA to mitigate
your body change your DNA to mitigate
your body change your DNA to mitigate that disease so that’s just one example
that disease so that’s just one example
that disease so that’s just one example but you know the idea being is that
but you know the idea being is that
but you know the idea being is that reprogramming you is incredibly powerful
reprogramming you is incredibly powerful
reprogramming you is incredibly powerful and we now have ways that are reliable
and we now have ways that are reliable
and we now have ways that are reliable in the clinic with all these different
in the clinic with all these different
in the clinic with all these different viruses that we can use for delivery all
viruses that we can use for delivery all
viruses that we can use for delivery all these hijackers that we can hijack that
these hijackers that we can hijack that
these hijackers that we can hijack that we can get to a wide variety cells and
we can get to a wide variety cells and
we can get to a wide variety cells and we can do a wide variety of things and
we can do a wide variety of things and
we can do a wide variety of things and we’re only limited by the delivery
we’re only limited by the delivery
we’re only limited by the delivery capability of the technology as it
capability of the technology as it
capability of the technology as it exists today and our knowledge of the
exists today and our knowledge of the
exists today and our knowledge of the drivers of disease and guess what both
drivers of disease and guess what both
drivers of disease and guess what both of those things are doubling or more
of those things are doubling or more
of those things are doubling or more every year and the cost of doing this
every year and the cost of doing this
every year and the cost of doing this stuff is cutting in half that sounds
stuff is cutting in half that sounds
stuff is cutting in half that sounds like a virtuous cycle to me
like a virtuous cycle to me
like a virtuous cycle to me it sounds like this is going to get
it sounds like this is going to get
it sounds like this is going to get better and better and better and I can
better and better and better and I can
better and better and better and I can tell you from 10 years in this industry
tell you from 10 years in this industry
tell you from 10 years in this industry it absolutely is and it will continue to
it absolutely is and it will continue to
it absolutely is and it will continue to do and what you can take away from this
do and what you can take away from this
do and what you can take away from this talk is that high tech has come to drug
talk is that high tech has come to drug
talk is that high tech has come to drug development and it’s gonna fire follow
development and it’s gonna fire follow
development and it’s gonna fire follow high tech curves and the bottom line is
high tech curves and the bottom line is
high tech curves and the bottom line is is that if you can dream it you can do
is that if you can dream it you can do
is that if you can dream it you can do it you don’t know when you’re gonna get
it you don’t know when you’re gonna get
it you don’t know when you’re gonna get there because you don’t know when you’re
there because you don’t know when you’re
there because you don’t know when you’re gonna understand how to unlock that
gonna understand how to unlock that
gonna understand how to unlock that thing you know what the drivers are what
thing you know what the drivers are what
thing you know what the drivers are what the interactions are in these diseases
the interactions are in these diseases
the interactions are in these diseases it’s incredibly complex your your
it’s incredibly complex your your
it’s incredibly complex your your genetics are not just your DNA it turns
genetics are not just your DNA it turns
genetics are not just your DNA it turns out we just discovered you know recently
out we just discovered you know recently
out we just discovered you know recently that there’s an epigenetic layer that
that there’s an epigenetic layer that
that there’s an epigenetic layer that alters your DNA and then we found out
alters your DNA and then we found out
alters your DNA and then we found out that this stuff that we used to call
that this stuff that we used to call
that this stuff that we used to call junk DNA that exists between different
junk DNA that exists between different
junk DNA that exists between different genes turns out not to be junk it turns
genes turns out not to be junk it turns
genes turns out not to be junk it turns out to be micro RNAs that can very
out to be micro RNAs that can very
out to be micro RNAs that can very hundreds of genes at one time so it’s
hundreds of genes at one time so it’s
hundreds of genes at one time so it’s really complex and there’s a lot of
really complex and there’s a lot of
really complex and there’s a lot of discovery that’s necessary but actually
discovery that’s necessary but actually
discovery that’s necessary but actually there’s a lot of low-hanging fruit
there’s a lot of low-hanging fruit
there’s a lot of low-hanging fruit that’s already been characterized and we
that’s already been characterized and we
that’s already been characterized and we already know how to work with it and so
already know how to work with it and so
already know how to work with it and so there’s a whole bunch of things that we
there’s a whole bunch of things that we
there’s a whole bunch of things that we can already address with the current
can already address with the current
can already address with the current technology in a very efficient way and
technology in a very efficient way and
technology in a very efficient way and it’s already happening so what’s the
it’s already happening so what’s the
it’s already happening so what’s the next step
next step
next step so I’ve already explained to you
so I’ve already explained to you
so I’ve already explained to you essentially how this works and I
essentially how this works and I
essentially how this works and I hopefully I’ve convinced you that it
hopefully I’ve convinced you that it
hopefully I’ve convinced you that it does work but let me give you some
does work but let me give you some
does work but let me give you some examples of how it’s working today so if
examples of how it’s working today so if
examples of how it’s working today so if you’ve been watching the newspaper you
you’ve been watching the newspaper you
you’ve been watching the newspaper you may have heard that to karti products
may have heard that to karti products
may have heard that to karti products have been approved so these are examples
have been approved so these are examples
have been approved so these are examples of what are called cell therapy or a
of what are called cell therapy or a
of what are called cell therapy or a form of gene therapy they’re basically
form of gene therapy they’re basically
form of gene therapy they’re basically altering cells we pull cells out of your
altering cells we pull cells out of your
altering cells we pull cells out of your body we alter them with viruses we
body we alter them with viruses we
body we alter them with viruses we reprogram their DNA to make them do
reprogram their DNA to make them do
reprogram their DNA to make them do something special and then we put them
something special and then we put them
something special and then we put them back in your body by the way I don’t see
back in your body by the way I don’t see
back in your body by the way I don’t see any timer around here so I apologize if
any timer around here so I apologize if
any timer around here so I apologize if I go over but anyway the so we we put
I go over but anyway the so we we put
I go over but anyway the so we we put them back in your body to do various
them back in your body to do various
them back in your body to do various jobs in your body and in the case of
jobs in your body and in the case of
jobs in your body and in the case of Carty what we’re doing is we’re taking
Carty what we’re doing is we’re taking
Carty what we’re doing is we’re taking out T cells which are the natural
out T cells which are the natural
out T cells which are the natural hunter-killer cells in your body that
hunter-killer cells in your body that
hunter-killer cells in your body that could wipe out anything anything that
could wipe out anything anything that
could wipe out anything anything that they turn their attention on they’ll
they turn their attention on they’ll
they turn their attention on they’ll kill and what we do is we take any old
kill and what we do is we take any old
kill and what we do is we take any old t—cell that comes out of your body and
t—cell that comes out of your body and
t—cell that comes out of your body and I don’t mean we cuz other companies but
I don’t mean we cuz other companies but
I don’t mean we cuz other companies but they put on the way that it decides what
they put on the way that it decides what
they put on the way that it decides what to pay attention to is something called
to pay attention to is something called
to pay attention to is something called an antigen receptor so you have these
an antigen receptor so you have these
an antigen receptor so you have these t-cells and you’ll have an infinite
t-cells and you’ll have an infinite
t-cells and you’ll have an infinite repertoire of these T cells you have T
repertoire of these T cells you have T
repertoire of these T cells you have T cells that are ready for anything
cells that are ready for anything
cells that are ready for anything diseases that you’ve never seen as a
diseases that you’ve never seen as a
diseases that you’ve never seen as a matter of fact most of the T cells will
matter of fact most of the T cells will
matter of fact most of the T cells will be born with you and will die with you
be born with you and will die with you
be born with you and will die with you never having seen the disease that they
never having seen the disease that they
never having seen the disease that they were looking for their entire life long
were looking for their entire life long
were looking for their entire life long but if they do meet that disease they’re
but if they do meet that disease they’re
but if they do meet that disease they’re amazingly effective what they do is that
amazingly effective what they do is that
amazingly effective what they do is that antigen receptor will send some surface
antigen receptor will send some surface
antigen receptor will send some surface protein it will get excited it’ll eat
protein it will get excited it’ll eat
protein it will get excited it’ll eat whatever that invader is could be
whatever that invader is could be
whatever that invader is could be bacteria could be a viral particle it
bacteria could be a viral particle it
bacteria could be a viral particle it could even be a cancerous cell and then
could even be a cancerous cell and then
could even be a cancerous cell and then it’ll get excited and stimulated and
it’ll get excited and stimulated and
it’ll get excited and stimulated and it’ll go back to the lymph nodes and
it’ll go back to the lymph nodes and
it’ll go back to the lymph nodes and it’ll bring back an army of itself to
it’ll bring back an army of itself to
it’ll bring back an army of itself to attack any of the leftover invaders that
attack any of the leftover invaders that
attack any of the leftover invaders that look like the invader that it just saw
look like the invader that it just saw
look like the invader that it just saw this is how it gets on top of a cold
this is how it gets on top of a cold
this is how it gets on top of a cold your cold is growing geometrically right
your cold is growing geometrically right
your cold is growing geometrically right but your immune system can replicate T
but your immune system can replicate T
but your immune system can replicate T cells so fast that if it didn’t stop
cells so fast that if it didn’t stop
cells so fast that if it didn’t stop your body weight would double in three
your body weight would double in three
your body weight would double in three days can you imagine that that’s how
days can you imagine that that’s how
days can you imagine that that’s how powerful your immune system is and it is
powerful your immune system is and it is
powerful your immune system is and it is great at killing so what how do they use
great at killing so what how do they use
great at killing so what how do they use that in blood-borne cancers okay car
that in blood-borne cancers okay car
that in blood-borne cancers okay car tease there’s two of them out there that
tease there’s two of them out there that
tease there’s two of them out there that have been approved in the last like
have been approved in the last like
have been approved in the last like three months this is how fastest is
three months this is how fastest is
three months this is how fastest is coming on to incurable cancers have an
coming on to incurable cancers have an
coming on to incurable cancers have an eighty percent cure rate now because
eighty percent cure rate now because
eighty percent cure rate now because they can reprogram t-cells to hunt down
they can reprogram t-cells to hunt down
they can reprogram t-cells to hunt down the cancerous b-cells because that’s
the cancerous b-cells because that’s
the cancerous b-cells because that’s where these blood cancers reside but
where these blood cancers reside but
where these blood cancers reside but they do it in kind of an odd way and
they do it in kind of an odd way and
they do it in kind of an odd way and it’s not really my favorite philosophy
it’s not really my favorite philosophy
it’s not really my favorite philosophy we have a different philosophy at AG T
we have a different philosophy at AG T
we have a different philosophy at AG T in terms of how we treat cancer
in terms of how we treat cancer
in terms of how we treat cancer hopefully I’ll get a moment to describe
hopefully I’ll get a moment to describe
hopefully I’ll get a moment to describe that to you but basically what they do
that to you but basically what they do
that to you but basically what they do is they take out these t-cells that
is they take out these t-cells that
is they take out these t-cells that might have been for the cold or in one
might have been for the cold or in one
might have been for the cold or in one foot of the flu or whatever so they just
foot of the flu or whatever so they just
foot of the flu or whatever so they just take out a big pool of these t-cells and
take out a big pool of these t-cells and
take out a big pool of these t-cells and they put a second antigen receptor on
they put a second antigen receptor on
they put a second antigen receptor on there that’s just looking for b-cells
there that’s just looking for b-cells
there that’s just looking for b-cells then they put it back in your body and
then they put it back in your body and
then they put it back in your body and they do exactly
they do exactly
they do exactly you’d expect they’d just wipe every
you’d expect they’d just wipe every
you’d expect they’d just wipe every b-cell out of your body and guess what
b-cell out of your body and guess what
b-cell out of your body and guess what they take the cancer with it it’s highly
they take the cancer with it it’s highly
they take the cancer with it it’s highly effective as I told you some of these
effective as I told you some of these
effective as I told you some of these cures are 80% in completely incurable
cures are 80% in completely incurable
cures are 80% in completely incurable cancers like pediatric acute
cancers like pediatric acute
cancers like pediatric acute lymphoblastic leukemia
lymphoblastic leukemia
lymphoblastic leukemia there’s it’s relatively curable in in
there’s it’s relatively curable in in
there’s it’s relatively curable in in children it’s not necessarily a death
children it’s not necessarily a death
children it’s not necessarily a death sentence when you hear it at first and
sentence when you hear it at first and
sentence when you hear it at first and it wasn’t before but a big percentage of
it wasn’t before but a big percentage of
it wasn’t before but a big percentage of those are incurable well guess what car
those are incurable well guess what car
those are incurable well guess what car 2 changed that it changed it in a
2 changed that it changed it in a
2 changed that it changed it in a profound way and this is what you’re
profound way and this is what you’re
profound way and this is what you’re going to see not just in blood borne
going to see not just in blood borne
going to see not just in blood borne cancers but in every cancer and AGT is
cancers but in every cancer and AGT is
cancers but in every cancer and AGT is on the cutting edge of this and we
on the cutting edge of this and we
on the cutting edge of this and we actually have a project in cancer that
actually have a project in cancer that
actually have a project in cancer that changes this philosophy the philosophy
changes this philosophy the philosophy
changes this philosophy the philosophy that we have is don’t treat the immune
that we have is don’t treat the immune
that we have is don’t treat the immune system the immune system is incredibly
system the immune system is incredibly
system the immune system is incredibly powerful but also incredibly complex and
powerful but also incredibly complex and
powerful but also incredibly complex and sensitive I don’t like the idea that
sensitive I don’t like the idea that
sensitive I don’t like the idea that these dual specific t-cells could float
these dual specific t-cells could float
these dual specific t-cells could float around in your body for a long time what
around in your body for a long time what
around in your body for a long time what happens when that other one gets
happens when that other one gets
happens when that other one gets stimulated and it replicates right in
stimulated and it replicates right in
stimulated and it replicates right in the lymph nodes and it brings back an
the lymph nodes and it brings back an
the lymph nodes and it brings back an army of by specific t-cells that are
army of by specific t-cells that are
army of by specific t-cells that are also looking for b-cells the flu and the
also looking for b-cells the flu and the
also looking for b-cells the flu and the b-cell who knows I mean you could be a
b-cell who knows I mean you could be a
b-cell who knows I mean you could be a ticking time bomb and believe me these
ticking time bomb and believe me these
ticking time bomb and believe me these companies are solving that problem with
companies are solving that problem with
companies are solving that problem with kill switches and stuff like that but
kill switches and stuff like that but
kill switches and stuff like that but for me that’s a little bit of kind of
for me that’s a little bit of kind of
for me that’s a little bit of kind of like spittin band-aids in order to sort
like spittin band-aids in order to sort
like spittin band-aids in order to sort of fix that problem but hey if it’s the
of fix that problem but hey if it’s the
of fix that problem but hey if it’s the best you got it’s the best you got so
best you got it’s the best you got so
best you got it’s the best you got so here’s how I think that cancers are
here’s how I think that cancers are
here’s how I think that cancers are gonna eventually be cured and this is
gonna eventually be cured and this is
gonna eventually be cured and this is what we’re doing at AG T we can go ahead
what we’re doing at AG T we can go ahead
what we’re doing at AG T we can go ahead and reprogram your cancer instead of
and reprogram your cancer instead of
and reprogram your cancer instead of your immune system we can make your
your immune system we can make your
your immune system we can make your cancer infinitely stimulatory to the
cancer infinitely stimulatory to the
cancer infinitely stimulatory to the exact T cells that surveil for cancer
exact T cells that surveil for cancer
exact T cells that surveil for cancer every day in your body here’s some more
every day in your body here’s some more
every day in your body here’s some more news for you besides the fact that
news for you besides the fact that
news for you besides the fact that you’re a stack of organic computers if I
you’re a stack of organic computers if I
you’re a stack of organic computers if I didn’t make you feel bad enough already
didn’t make you feel bad enough already
didn’t make you feel bad enough already this 1×1 will get you every single
this 1×1 will get you every single
this 1×1 will get you every single person in this audience has cancer big
person in this audience has cancer big
person in this audience has cancer big deal
deal
deal doesn’t matter you get cancer every day
doesn’t matter you get cancer every day
doesn’t matter you get cancer every day usually it’s little you know small
usually it’s little you know small
usually it’s little you know small occurrences of you know
occurrences of you know
occurrences of you know single cells that stress out that have
single cells that stress out that have
single cells that stress out that have had too much chemicals radiation stress
had too much chemicals radiation stress
had too much chemicals radiation stress or just have aged out and in trying to
or just have aged out and in trying to
or just have aged out and in trying to survive they may go cancerous and then
survive they may go cancerous and then
survive they may go cancerous and then you have these specialized t-cells that
you have these specialized t-cells that
you have these specialized t-cells that mop them up like it’s nothing it’s
mop them up like it’s nothing it’s
mop them up like it’s nothing it’s absolutely no threat to you and as a
absolutely no threat to you and as a
absolutely no threat to you and as a matter of fact my recommendation to you
matter of fact my recommendation to you
matter of fact my recommendation to you if you want to avoid what we call cancer
if you want to avoid what we call cancer
if you want to avoid what we call cancer which is actually solid tumors is relax
which is actually solid tumors is relax
which is actually solid tumors is relax all right
all right
all right stress is the big killer so stressful
stress is the big killer so stressful
stress is the big killer so stressful will diminish your immune system and
will diminish your immune system and
will diminish your immune system and increase your stress all right that’s
increase your stress all right that’s
increase your stress all right that’s great conditions for disease so relax
great conditions for disease so relax
great conditions for disease so relax meditate whatever it does it for you but
meditate whatever it does it for you but
meditate whatever it does it for you but don’t worry about cancer okay so relax
don’t worry about cancer okay so relax
don’t worry about cancer okay so relax after what I just told you you don’t
after what I just told you you don’t
after what I just told you you don’t have real cancer you just have normal
have real cancer you just have normal
have real cancer you just have normal immune system mopping up problems in
immune system mopping up problems in
immune system mopping up problems in your body like it does all the time so
your body like it does all the time so
your body like it does all the time so here’s what we do though that immune
here’s what we do though that immune
here’s what we do though that immune system could be stimulated those
system could be stimulated those
system could be stimulated those specialized t-cells what happens is is
specialized t-cells what happens is is
specialized t-cells what happens is is when a cancer turns into a tumor what
when a cancer turns into a tumor what
when a cancer turns into a tumor what what’s occurred is that it’s hit a
what’s occurred is that it’s hit a
what’s occurred is that it’s hit a critical mass point where it’s growing
critical mass point where it’s growing
critical mass point where it’s growing faster than your immune system is able
faster than your immune system is able
faster than your immune system is able to chew it away there can be lots of
to chew it away there can be lots of
to chew it away there can be lots of reasons for that I don’t say that I
reasons for that I don’t say that I
reasons for that I don’t say that I understand it all or even much of it but
understand it all or even much of it but
understand it all or even much of it but the bottom line is is at some point your
the bottom line is is at some point your
the bottom line is is at some point your immune system just can’t get at it as
immune system just can’t get at it as
immune system just can’t get at it as fast but it gets even worse cancer is
fast but it gets even worse cancer is
fast but it gets even worse cancer is evolved in the same way that everything
evolved in the same way that everything
evolved in the same way that everything is evolved and cancer has discovered
is evolved and cancer has discovered
is evolved and cancer has discovered ways to disguise itself against the very
ways to disguise itself against the very
ways to disguise itself against the very immune cells that are supposed to be
immune cells that are supposed to be
immune cells that are supposed to be mopping it up
mopping it up
mopping it up it throws what are called checkpoint
it throws what are called checkpoint
it throws what are called checkpoint inhibitors out on the surface and these
inhibitors out on the surface and these
inhibitors out on the surface and these act as traffic cops that tell the immune
act as traffic cops that tell the immune
act as traffic cops that tell the immune system hey nothing to see here move on
system hey nothing to see here move on
system hey nothing to see here move on by I mean it really has that effect
by I mean it really has that effect
by I mean it really has that effect you’ve probably heard of some of them
you’ve probably heard of some of them
you’ve probably heard of some of them like PDL one that’s a giant giant drug
like PDL one that’s a giant giant drug
like PDL one that’s a giant giant drug category for Merck they may have
category for Merck they may have
category for Merck they may have something called somebody help me out
something called somebody help me out
something called somebody help me out here okay nobody’s gonna okay well they
here okay nobody’s gonna okay well they
here okay nobody’s gonna okay well they have a PDL one blocker and there’s
have a PDL one blocker and there’s
have a PDL one blocker and there’s another one from a V I mean they’re all
another one from a V I mean they’re all
another one from a V I mean they’re all over the place but the PDL one blocker
over the place but the PDL one blocker
over the place but the PDL one blocker is will go ahead and sort of shield that
is will go ahead and sort of shield that
is will go ahead and sort of shield that camouflage that cell surface protein
camouflage that cell surface protein
camouflage that cell surface protein that’s acting as a traffic cop
that’s acting as a traffic cop
that’s acting as a traffic cop they put a monoclonal and
they put a monoclonal and
they put a monoclonal and on top of it and it blocks it and the
on top of it and it blocks it and the
on top of it and it blocks it and the immune system starts to see the cancer
immune system starts to see the cancer
immune system starts to see the cancer again and in fact it’s that Merck drug
again and in fact it’s that Merck drug
again and in fact it’s that Merck drug that turned out that it pushed Jimmy
that turned out that it pushed Jimmy
that turned out that it pushed Jimmy Carter over the line from being
Carter over the line from being
Carter over the line from being untreatable to treatable and may have
untreatable to treatable and may have
untreatable to treatable and may have saved his life that little teeny
saved his life that little teeny
saved his life that little teeny addition of just D cloaking the cancer
addition of just D cloaking the cancer
addition of just D cloaking the cancer for your immune system and allowing the
for your immune system and allowing the
for your immune system and allowing the immune system do it to do its normal job
immune system do it to do its normal job
immune system do it to do its normal job instead of being faked out was something
instead of being faked out was something
instead of being faked out was something that made the difference between
that made the difference between
that made the difference between incurable and curable so it’s very very
incurable and curable so it’s very very
incurable and curable so it’s very very powerful but what we can do when we
powerful but what we can do when we
powerful but what we can do when we reprogram the cancer is much much more
reprogram the cancer is much much more
reprogram the cancer is much much more so we can go ahead and we can slip in
so we can go ahead and we can slip in
so we can go ahead and we can slip in things that just tell the cells to stop
things that just tell the cells to stop
things that just tell the cells to stop making those cell surface proteins so we
making those cell surface proteins so we
making those cell surface proteins so we can go ahead and decloak the cancer but
can go ahead and decloak the cancer but
can go ahead and decloak the cancer but even more importantly we can convert a
even more importantly we can convert a
even more importantly we can convert a bunch of those cells into factories
bunch of those cells into factories
bunch of those cells into factories basically that create a little substance
basically that create a little substance
basically that create a little substance called a peptide that is stimulatory to
called a peptide that is stimulatory to
called a peptide that is stimulatory to the immune system it will drive your
the immune system it will drive your
the immune system it will drive your immune system to 300 to 600 times its
immune system to 300 to 600 times its
immune system to 300 to 600 times its normal activity and those cancers just
normal activity and those cancers just
normal activity and those cancers just melt away and we’re seeing that in mouse
melt away and we’re seeing that in mouse
melt away and we’re seeing that in mouse models right now so I’m getting some
models right now so I’m getting some
models right now so I’m getting some signals that I got to wrap this thing up
signals that I got to wrap this thing up
signals that I got to wrap this thing up so I’ll go very quickly to my point so
so I’ll go very quickly to my point so
so I’ll go very quickly to my point so you heard about to car tease well when I
you heard about to car tease well when I
you heard about to car tease well when I saw this technology I said to my friends
saw this technology I said to my friends
saw this technology I said to my friends you’re gonna see a steady stream of
you’re gonna see a steady stream of
you’re gonna see a steady stream of miracles you’re gonna see people getting
miracles you’re gonna see people getting
miracles you’re gonna see people getting out of their wheelchairs and walking
out of their wheelchairs and walking
out of their wheelchairs and walking you’re gonna see blind people seeing
you’re gonna see blind people seeing
you’re gonna see blind people seeing again you’re gonna the lepers will be
again you’re gonna the lepers will be
again you’re gonna the lepers will be cured it really is that sort of nature I
cured it really is that sort of nature I
cured it really is that sort of nature I mean that’s the power of this thing and
mean that’s the power of this thing and
mean that’s the power of this thing and in fact it’s happening right now some of
in fact it’s happening right now some of
in fact it’s happening right now some of you may have heard of Lux torna Lux
you may have heard of Lux torna Lux
you may have heard of Lux torna Lux tornado is just unanimously recommended
tornado is just unanimously recommended
tornado is just unanimously recommended for approval by the committee by the FDA
for approval by the committee by the FDA
for approval by the committee by the FDA committee for treating a form of
committee for treating a form of
committee for treating a form of inherited blindness it’s so effective
inherited blindness it’s so effective
inherited blindness it’s so effective that a woman who was legally blind who
that a woman who was legally blind who
that a woman who was legally blind who can’t read who cannot navigate a room
can’t read who cannot navigate a room
can’t read who cannot navigate a room without a cane is getting her driver’s
without a cane is getting her driver’s
without a cane is getting her driver’s license and and we have no reason to
license and and we have no reason to
license and and we have no reason to fear she can actually see just fine so
fear she can actually see just fine so
fear she can actually see just fine so don’t worry that they’re out there I
don’t worry that they’re out there I
don’t worry that they’re out there I mean that’s miraculous right and that’s
mean that’s miraculous right and that’s
mean that’s miraculous right and that’s what you’re going to see in the future
what you’re going to see in the future
what you’re going to see in the future with gene therapy a drip drip drip over
with gene therapy a drip drip drip over
with gene therapy a drip drip drip over this next year or so of these miracle
this next year or so of these miracle
this next year or so of these miracle cures
cures
cures followed by a steady stream followed by
followed by a steady stream followed by
followed by a steady stream followed by a deluge followed by a point where you
a deluge followed by a point where you
a deluge followed by a point where you just wonder what did we ever do how did
just wonder what did we ever do how did
just wonder what did we ever do how did we live without gene therapy it’s gonna
we live without gene therapy it’s gonna
we live without gene therapy it’s gonna be like your cell phone and GPS and the
be like your cell phone and GPS and the
be like your cell phone and GPS and the internet you’re gonna forget the day
internet you’re gonna forget the day
internet you’re gonna forget the day that you had it you’re gonna be telling
that you had it you’re gonna be telling
that you had it you’re gonna be telling your grandchildren we used to treat
your grandchildren we used to treat
your grandchildren we used to treat cancer with ionizing radiation and
cancer with ionizing radiation and
cancer with ionizing radiation and deadly chemicals we used to poison you
deadly chemicals we used to poison you
deadly chemicals we used to poison you hope the cancer died and then you
hope the cancer died and then you
hope the cancer died and then you recovered well that kind of treatment
recovered well that kind of treatment
recovered well that kind of treatment for cancer is gonna go the way of
for cancer is gonna go the way of
for cancer is gonna go the way of bloodletting and leeches I promise you
bloodletting and leeches I promise you
bloodletting and leeches I promise you I’ve seen the pattern it all has to do
I’ve seen the pattern it all has to do
I’ve seen the pattern it all has to do with the high-tech nature of this the
with the high-tech nature of this the
with the high-tech nature of this the capabilities keep increasing we’re going
capabilities keep increasing we’re going
capabilities keep increasing we’re going to address more and more diseases we’re
to address more and more diseases we’re
to address more and more diseases we’re going to find effective cures for things
going to find effective cures for things
going to find effective cures for things that are nothing short of miraculous the
that are nothing short of miraculous the
that are nothing short of miraculous the costs are going to keep going down it’s
costs are going to keep going down it’s
costs are going to keep going down it’s going to absolutely change healthcare
going to absolutely change healthcare
going to absolutely change healthcare forever for the better and it’s a very
forever for the better and it’s a very
forever for the better and it’s a very exciting future that we’re going into
exciting future that we’re going into
exciting future that we’re going into thank you
thank you
thank you [Applause]
”
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