people do not see anyone helps a little
how to sing right?
and I wanted to start by thanking you
ted’s personal with the invitation
felipe guilherme in particular and the
dani is the park’s staff
there and davi for giving strength to
to build a script for this
history and the story that I wanted
telling you is the story of a
ball is not exactly my
story but you will see that I
I am involved with the history of this
little ball to talk a little about
The story of this little ball is very
important to first establish this map
that you are seeing there on the screen the
I would like to show on this map
on this map you are seeing two
public health problems of the
high relevance to a time when
we live
you see on the right side there is the map
of AIDS that is known to no one
this would be a problem of the highest
relevance to the whole world and
You come from the left side.
the distribution map of the
schistosomiasis
schistosomiasis is a disease that
people got used to studying in the second
degree but we hear and speak little
she does not receive much attention from her
is called a neglected disease by
Why, because if you look with
attention the map that is here behind
you will realize that the
schistosomiasis they are distributed
mainly between poor countries and
poor people who do not have
money to buy drugs or
pay for health treatments and that side
of this disease makes the
large laboratories that take care of
treatment of people development of
do not take too much care of the
schistosomiasis
although in absolute terms it perceives
you do not notice I’m not comparing
importance of diseases
but if you compare the number of
people affected by the disease
it would be no exaggeration to say that
I’m moss it ‘s a problem ten months
more important than AIDS in terms
of the number of people who become ill
and despite this she has much less
visibility of what AIDS is a
more democratic disease that attacks
countries and poor countries and
therefore affects people who have
condition of treatment is a
aspect is private
It is from this disease that schistosomiasis
is what makes the problem
Even more serious social view is that
commits children
Schistosomiasis causes the famous belly
water is the belly of water
account of the infestation
some organs of the organism for a
worm it grows accumulates liquids cause
is all kind of physiological problem and
she can even kill and she attacks
especially children because
children have a good habit of
entertain with water and schistosomiasis in the
cycle that it develops
You are seeing a photo and it is very
ust of the worm that attacks the
Kids is horrible goal is over
cause this sense of repudiation
he creates he has a phase of life that
it is inside the organism it attacks the
liver the spleen at destination is housed in
certain portions of the body and
put an absurd amount of eggs at
and for the development of the
natural of that of that worm the eggs
they need to find hatching in.
of a snail that is
found one infected with faeces of the
people is to help the development of
second stage of disease , and to
hatching and the development of the larva
which eventually returns to being
contaminated water is
like children
are in rivers more frequently than
that adults
how are they playing with the waters
more frequently polluted
than adults
they are most often
the disease than the
adults
this also helps to explain why
this disease develops
especially in poor countries is
because in poor countries
the cleaning and sanitation system
generally a little worse than
developed countries for you
treating this disease as it is a
neglected disease and it receives little
attention of large laboratories and
little attention from large
pharmaceutical conglomerates are few
the chemicals that can
be used to treat this disease
Are you seeing there in the
chemical formula I’m an engineer
chemist had to find a way to
present the chemical formula I found
It’s not that ugly shape they’re seeing.
there the praziquantel, which is the medicine
a compound that is most popular is the
most used worldwide to treat
to schistosomiasis
What is the term problem with theo?
here we have two serious problems
of this medicine
problem number one it’s bitter to
He’s very bitter and I know
because I too have taken and
this remedy and this causes a problem
when it is going to be given to the
child who tends to reject this
medicine it tends to vomit the
refuse
she does not want to take it after taking
time is the one you hardly want to take
second, and this harms the
treatment of the disease and two
reduces the effectiveness of the
CV treatment of schistosomiasis
adding a series of small
factors is not what make this scenario
so dramatic for poor countries
like Brazil that are affected by
those diseases that are said
It is estimated that in Brazil, despite the
low visibility of issues o nosi
there are between 5 and 8 million people
schistosomiasis patients we see who is
a problem of enormous magnitude
and this drug this compound
chemist has another problem like
child or the person needs to take
large quantities of this medicine
to be able to end up with money
installed inside the body
the tablets are very large as
the tablets are very large and the
doses are too large again.
children reject the drug because
it is difficult to swallow and it forces the mother
the child for example until he distributes
the size of the remedy to suit
there is the child’s weight
all this hinders the treatment and
efficiency and effectiveness of the
fight against schistosomiasis
for this reason the ministry of health
is transformed the problem of
schistosomiasis in one of the priorities
of public health in Brazil is in
the ministry of health seeks to
a solution of praziquantel remedy
a pharmaceutical formulation of beach
Hotel
the medicine used to treat
schistosomiasis that does not taste
because it would be possible or
it will be possible to reduce the resistance
children have with the medicine
a possible solution for this
problem is that you are seeing there
on the screen is we hide or how to
people talk and technically encapsulate this
sufficiently polished medicinal product
so that children can
take the medicine and I do not feel the taste
of the drug
this picture that you are seeing in
it represents particles that have
100 nanometer size remembering
who did not take the science course
exact
a nanometer means millionth
part of the subway is a very
really small
It estimated the thousand times order has a
diameter of this ball a thousand times smaller
that the diameter of a hair is
a typical text that appears when the
people talk about us
technology and the idea is to put the
remedy inside this ball for
He does not contact Easter.
the taste buds and the child thus
I do not feel like not feeling the taste
she refuses to reject the problem I learned
that in engineering
every major major problem begins
with an understanding a simple problem
like this
the medicine that tastes bad the most
you put the medicine inside
a ball of 100 nanometers is what it is
a very sophisticated technology that
ball can not be too much
great because if it is too big
it will cause a feeling of a sand
something that irritates and the child
person will reject again then the
We have to have a lot of control.
appropriate for the size of this ball to
that the solution is effective
Good, we try to solve problems.
like this one in a coppe lab
called in Japan the laboratory of
engineering of polymers
What are you seeing there in this photo?
is an installation that allows the
people call scheduling
processes that is transforming a thing
what we do in the tiny
quantities within the laboratory in
quantities which are sufficiently
great for them to have important
social importance and we have developed
a technological solution to produce
this little ball and produce the remedy for
to combat schistosomiasis without taste
and then I wanted to get that nickname and
converge to actually what is the
message the main topic that I
I would like to discuss with you
You do not want to think what to say. 10
minutes about what is not the theme
central theme here is that the
university is prepared and she
must actually undertake to listen to the
society and listen to the problems that
society is very common to see
still inside the university and I’m going
here is talking about the controversial topic
but I usually play with my kids
I’m going to be 53 years old already.
talk what you think or I will have
opportunity to speak what I think never
and there are people at university sometimes
has a speech of academic freedom
the teacher of the researcher who actually
people have to think what we people
We want in fact we have to say
that we want but we have to
be with ears open to
needs of society in particular
in Brazilian society then full of
problems like here, how’s that?
we have university she has to
obligation to look for an extension
the knowledge it develops for the
society that surrounds us
it does not matter that we researchers
we got stuck in an ivory tower
studying themes that we consider the
more relevant if this knowledge of
somehow society does not
benefits society in some way
in particular it is important to say
I’m a 30-year university professor.
and I’m paid for you guys are
watching at this time then we
has an obligation to give back to whom
pays us that it is the society that
houses and what are not lacking are problems
In Brazil, we care for them and
try to solve I ‘m saying that the
university does not participate in this
process
on the contrary who is helping
who is following the question
of the zico at this moment knows that the
universities research institutes
are trying to get involved
possible with the theme but you need
do more and we have another one
a very serious problem in Brazil that
hinders this entrepreneurial issue
which is called bureaucracy or bureaucracy
When we want to speak ill of her, we
country has become accustomed to demanding
absurdly large amount of
control of all types so that the
people to be able to undertake and
sometimes makes it almost impossible for you
to undertake in the country
I’ll give you an example that
have to do with the story of this little ball
and be very clear I ‘m not here
Complaining I’m counting a
story in this project by
For example, we are one year
Federal University of Rio de Janeiro
has decided to develop the
medical solution the ministry of
Cheers
agree to develop the solution
medical bnds agree to develop aa
economic support for the development of
this medical solution to
agrees to be a partner in this process
and we have not been able for a year
to sign a partnership agreement for
certificate silk bureaucracy bill
addition to the certificate of that of the
of such a thing that has to be
done and in the country we forget that
important is to do if we push the
entrepreneur process
we could not do it and we did not
we were able to move forward
I like to imagine that this one even has
a very large number of people
of small age is low among
something much under 20 years good part
between 20 and 30 years and you have
obligation to change this
Brazil certainly contains with my
support there are several places in
university where we teach this
obligation to undertake and where people
learns this obligation to undertake
I have some examples here is a
number that has impressed me since I
I arrived at the technology park was
there are 700 entrepreneurial movements
cataloged by independent ufrj
It is an absurdly large number
part of you who are here who
is here and that the
entrepreneurial movement knows this more
this number and these initiatives
has the visibility she deserves
we need to deepen this question
entrepreneur at university
we see the companies geniuses who
plays a very important role in the way
these people
the incubator of companies where its good
idea needs to be supported by
university to turn into
a good company that will help
solve your problems
good company that can be received and
very well received in the park
ufrj technology
We then have paths that do not
It means we’re fine.
not what I’m saying is that there are
paths and that we have to
to deepen the profile and lead to
all these movements within the UFRJ I
I really like this picture because here
new we have to see two graphs
on your left side
you see the scientific production
brazil today brasil occupies the
depend on the ranking in a position
between 14th and 11th place among the highest
producer of knowledge research in the
world what is a cool thing yet
not comparable to the size of our
economy but is not a number of which
we are ashamed
However when we talk about
innovation and entrepreneurial activities
not start in the world that puts the
brazil above the 70th position, which
it means that it illustrates
cabral that we are sinning
and sinning in our
ability to bring knowledge
generated within institutions
to the society that maintains
these institutions and need to see
their problems solved and supported
by those who are thinking then
I wanted to finish this presentation.
with this photo that shows again the
a solution developed in the
Federal University of Rio de
January and talks so much about the
difficulties we have to generate
to raise the knowledge that we
we produce society the most
need that actually keeps us
this is our obligation and it is for
This is what I wanted to leave this message
Last
we have the mission and obligation to
undertake to transform the
Brazilian public university follow
forward and respond to this call
I’m a partner in this fight, big hug.
for everyone
[Applause]
”
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