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Mending Broken Hearts | Renata Gomes | TEDxAveiro


[Music]

[Music] I must have been 14 maybe 15 years old

I must have been 14 maybe 15 years old

I must have been 14 maybe 15 years old as I left school as always I know ask me

as I left school as always I know ask me

as I left school as always I know ask me why I was making sure my tight worst my

why I was making sure my tight worst my

why I was making sure my tight worst my tie was straight and I had no stains my

tie was straight and I had no stains my

tie was straight and I had no stains my school uniform but the next thing I

school uniform but the next thing I

school uniform but the next thing I remember hearing is grandad is in the

remember hearing is grandad is in the

remember hearing is grandad is in the hospital he had a heart attack I will

hospital he had a heart attack I will

hospital he had a heart attack I will never forget he was a Tuesday and on

never forget he was a Tuesday and on

never forget he was a Tuesday and on every Tuesday I used to go running with

every Tuesday I used to go running with

every Tuesday I used to go running with my grandfather this is my grandfather

my grandfather this is my grandfather

my grandfather this is my grandfather that survived war he’s been in military

that survived war he’s been in military

that survived war he’s been in military deployments and he survived extremism

deployments and he survived extremism

deployments and he survived extremism but at that moment my grandfather was

but at that moment my grandfather was

but at that moment my grandfather was being killed by his own heart I went

being killed by his own heart I went

being killed by his own heart I went running straight away to the hospital in

running straight away to the hospital in

running straight away to the hospital in eyes as I entered the hospital I saw him

eyes as I entered the hospital I saw him

eyes as I entered the hospital I saw him sitting pale sick and worried in a

sitting pale sick and worried in a

sitting pale sick and worried in a hospital bed next to him there was a

hospital bed next to him there was a

hospital bed next to him there was a pile of papers and these papers had a

pile of papers and these papers had a

pile of papers and these papers had a drawing of a heart and notes from his

drawing of a heart and notes from his

drawing of a heart and notes from his surgeon the surgeon told me I’m going to

surgeon the surgeon told me I’m going to

surgeon the surgeon told me I’m going to patch your grandfather’s heart tomorrow

patch your grandfather’s heart tomorrow

patch your grandfather’s heart tomorrow morning but he said to patch it up not

morning but he said to patch it up not

morning but he said to patch it up not mend it and I really wondered what was

mend it and I really wondered what was

mend it and I really wondered what was going to happen to my grandfather and

going to happen to my grandfather and

going to happen to my grandfather and actually at that moment I never really

actually at that moment I never really

actually at that moment I never really paid much attention to hearts any hearts

paid much attention to hearts any hearts

paid much attention to hearts any hearts even my own let me ask you a question

even my own let me ask you a question

even my own let me ask you a question how many of you have been checking your

how many of you have been checking your

how many of you have been checking your heart lately

heart lately

heart lately raise your hands if you have checked

raise your hands if you have checked

raise your hands if you have checked your heart well this is reflective that

your heart well this is reflective that

your heart well this is reflective that we really don’t pay much attention to

we really don’t pay much attention to

we really don’t pay much attention to our hearts in fact we very evil to our

our hearts in fact we very evil to our

our hearts in fact we very evil to our hearts 95% of what all vascular disease

hearts 95% of what all vascular disease

hearts 95% of what all vascular disease is preventable a few changes in our diet

is preventable a few changes in our diet

is preventable a few changes in our diet our lifestyle increased heart an

our lifestyle increased heart an

our lifestyle increased heart an increased exercise would really make us

increased exercise would really make us

increased exercise would really make us better

better

better in fact we are so Cruella Deville that

in fact we are so Cruella Deville that

in fact we are so Cruella Deville that 60% of us in this room will die for

60% of us in this room will die for

60% of us in this room will die for cardiovascular disease or is

cardiovascular disease or is

cardiovascular disease or is ramifications so I thought as a young

ramifications so I thought as a young

ramifications so I thought as a young graduate in 2007 that I was going to do

graduate in 2007 that I was going to do

graduate in 2007 that I was going to do something about it and early 2008 I

something about it and early 2008 I

something about it and early 2008 I really despaired and I was looking out

really despaired and I was looking out

really despaired and I was looking out of the window at University College

of the window at University College

of the window at University College London labs and I saw the building in

London labs and I saw the building in

London labs and I saw the building in front it was full of cement and building

front it was full of cement and building

front it was full of cement and building works and I saw they were building the

works and I saw they were building the

works and I saw they were building the London Center for nanotechnology so I

London Center for nanotechnology so I

London Center for nanotechnology so I looked at it and I thought my stem cells

looked at it and I thought my stem cells

looked at it and I thought my stem cells and I’m really not going to fix this

and I’m really not going to fix this

and I’m really not going to fix this problem so I’d need to do something

problem so I’d need to do something

problem so I’d need to do something about it why not use nanotechnology to

about it why not use nanotechnology to

about it why not use nanotechnology to sort this problem and I really thought I

sort this problem and I really thought I

sort this problem and I really thought I was sleep deprived going insane because

was sleep deprived going insane because

was sleep deprived going insane because I was totally ignorant I just actually

I was totally ignorant I just actually

I was totally ignorant I just actually learnt the word nanotechnology I had no

learnt the word nanotechnology I had no

learnt the word nanotechnology I had no idea what that was so the next thing I

idea what that was so the next thing I

idea what that was so the next thing I know a few months later a few too many

know a few months later a few too many

know a few months later a few too many emails I set up a system by which I

emails I set up a system by which I

emails I set up a system by which I would research and for distant areas

would research and for distant areas

would research and for distant areas totally different areas of research

totally different areas of research

totally different areas of research involving at least six different

involving at least six different

involving at least six different universities in three different

universities in three different

universities in three different countries and I tell you held two

countries and I tell you held two

countries and I tell you held two conference calls and direct flights I

conference calls and direct flights I

conference calls and direct flights I wanted to create a system to deliver

wanted to create a system to deliver

wanted to create a system to deliver drugs in stem cells and get these to go

drugs in stem cells and get these to go

drugs in stem cells and get these to go into your broken heart and really help

into your broken heart and really help

into your broken heart and really help it to be mended the system would consist

it to be mended the system would consist

it to be mended the system would consist of something brand new a totally novel

of something brand new a totally novel

of something brand new a totally novel nanoparticle or none of thing I used to

nanoparticle or none of thing I used to

nanoparticle or none of thing I used to call it and we would be able to deliver

call it and we would be able to deliver

call it and we would be able to deliver delivered drugs with it so these cells

delivered drugs with it so these cells

delivered drugs with it so these cells which we were putting in very hostile

which we were putting in very hostile

which we were putting in very hostile situations with actually solved at the

situations with actually solved at the

situations with actually solved at the time the major problems were one you

time the major problems were one you

time the major problems were one you couldn’t really get stem cells to

couldn’t really get stem cells to

couldn’t really get stem cells to survive in an impacted myocardium

survive in an impacted myocardium

survive in an impacted myocardium because it was a really hostile area was

because it was a really hostile area was

because it was a really hostile area was a bit like putting these stem cells into

a bit like putting these stem cells into

a bit like putting these stem cells into a warzone and number two we really

a warzone and number two we really

a warzone and number two we really didn’t have a system that could deliver

didn’t have a system that could deliver

didn’t have a system that could deliver drugs and be trackable over time so I

drugs and be trackable over time so I

drugs and be trackable over time so I thought let’s do this and in fact we

thought let’s do this and in fact we

thought let’s do this and in fact we created a system by which it was all

created a system by which it was all

created a system by which it was all biocompatible and ideal for human usage

biocompatible and ideal for human usage

biocompatible and ideal for human usage obviously that was so 2030 right often

obviously that was so 2030 right often

obviously that was so 2030 right often simple ideas involved very complex

simple ideas involved very complex

simple ideas involved very complex experimentation

experimentation

experimentation we went all the way from developing

we went all the way from developing

we went all the way from developing physical instruments to surgical

physical instruments to surgical

physical instruments to surgical apparatus

apparatus

apparatus I used my initiative and I was

I used my initiative and I was

I used my initiative and I was definitely not afraid can you we do it

definitely not afraid can you we do it

definitely not afraid can you we do it yes we can’t and a few years later that

yes we can’t and a few years later that

yes we can’t and a few years later that day had arrived the day which the data

day had arrived the day which the data

day had arrived the day which the data show we could do it I really remember it

show we could do it I really remember it

show we could do it I really remember it I was in Northville in Finland I spent

I was in Northville in Finland I spent

I was in Northville in Finland I spent the whole winter in there and I had not

the whole winter in there and I had not

the whole winter in there and I had not seen any natural daylight for a long

seen any natural daylight for a long

seen any natural daylight for a long time in fact I was really really looking

time in fact I was really really looking

time in fact I was really really looking forward to the good weather in London

forward to the good weather in London

forward to the good weather in London ironic isn’t it

ironic isn’t it

ironic isn’t it so just before I left and I boarded that

so just before I left and I boarded that

so just before I left and I boarded that flight I got a call from a supervisor

flight I got a call from a supervisor

flight I got a call from a supervisor saying well done I never thought you

saying well done I never thought you

saying well done I never thought you would do it you’ve got so lucky this is

would do it you’ve got so lucky this is

would do it you’ve got so lucky this is pretty much impossible and just a note

pretty much impossible and just a note

pretty much impossible and just a note on luck I don’t believe in luck um luck

on luck I don’t believe in luck um luck

on luck I don’t believe in luck um luck is a very very difficult business you

is a very very difficult business you

is a very very difficult business you have to really work hard to get this

have to really work hard to get this

have to really work hard to get this thing which cold luck which is based on

thing which cold luck which is based on

thing which cold luck which is based on hard work anyway so I decided to move on

hard work anyway so I decided to move on

hard work anyway so I decided to move on myself with my luck

myself with my luck

myself with my luck like Einstein said life is like riding a

like Einstein said life is like riding a

like Einstein said life is like riding a bicycle you must keep moving to keep

bicycle you must keep moving to keep

bicycle you must keep moving to keep your balance so I wanted to do something

your balance so I wanted to do something

your balance so I wanted to do something bigger and better

bigger and better

bigger and better I needed a system that was both

I needed a system that was both

I needed a system that was both therapeutic and preventive there is

therapeutic and preventive there is

therapeutic and preventive there is nothing like that currently until I went

nothing like that currently until I went

nothing like that currently until I went back to drawing board actually not the

back to drawing board actually not the

back to drawing board actually not the drawing board the napkins because I

drawing board the napkins because I

drawing board the napkins because I drink far too much coffee don’t do that

drink far too much coffee don’t do that

drink far too much coffee don’t do that is really bad for your heart and yes I

is really bad for your heart and yes I

is really bad for your heart and yes I came up with a new system where I wanted

came up with a new system where I wanted

came up with a new system where I wanted I actually went ahead I took my own

I actually went ahead I took my own

I actually went ahead I took my own blood I isolated this type of cells from

blood I isolated this type of cells from

blood I isolated this type of cells from my blood label it with a new super power

my blood label it with a new super power

my blood label it with a new super power system and we injected by in our bone

system and we injected by in our bone

system and we injected by in our bone blood and what we were doing is that we

blood and what we were doing is that we

blood and what we were doing is that we are keeping vessel integrity by making

are keeping vessel integrity by making

are keeping vessel integrity by making sure that at early injury at early

sure that at early injury at early

sure that at early injury at early injury all becomes well the vessels

injury all becomes well the vessels

injury all becomes well the vessels don’t get damaged we don’t get rupture

don’t get damaged we don’t get rupture

don’t get damaged we don’t get rupture and we don’t get broken hearts so this

and we don’t get broken hearts so this

and we don’t get broken hearts so this whole business of many broken hearts

whole business of many broken hearts

whole business of many broken hearts went very extreme because I had to get

went very extreme because I had to get

went very extreme because I had to get leaders from all over the world a

leaders from all over the world a

leaders from all over the world a scientific world in fact I was working

scientific world in fact I was working

scientific world in fact I was working under the same lab as Israel e-juice

under the same lab as Israel e-juice

under the same lab as Israel e-juice Palestinian Muslims and we are working

Palestinian Muslims and we are working

Palestinian Muslims and we are working in harmony I also had to deploy military

in harmony I also had to deploy military

in harmony I also had to deploy military experts and we really went all the way

experts and we really went all the way

experts and we really went all the way to be together inside and outside the

to be together inside and outside the

to be together inside and outside the lab so outside the lab I made an effort

lab so outside the lab I made an effort

lab so outside the lab I made an effort to Reyn to join runners without

to Reyn to join runners without

to Reyn to join runners without boundaries and human terian eighteens

boundaries and human terian eighteens

boundaries and human terian eighteens unlikely missions I used to get shouted

unlikely missions I used to get shouted

unlikely missions I used to get shouted a lot to the soldiers and that’s where

a lot to the soldiers and that’s where

a lot to the soldiers and that’s where the Spitfire comes from that’s what they

the Spitfire comes from that’s what they

the Spitfire comes from that’s what they call me and the reason was is because

call me and the reason was is because

call me and the reason was is because without that helmet and that eye

without that helmet and that eye

without that helmet and that eye protection

protection

protection I could go blind any simple accident and

I could go blind any simple accident and

I could go blind any simple accident and you go blind

you go blind

you go blind now I’m going ask you something please

now I’m going ask you something please

now I’m going ask you something please close your eyes but really close it you

close your eyes but really close it you

close your eyes but really close it you have it open and now imagine how it will

have it open and now imagine how it will

have it open and now imagine how it will be like to go blind you probably it’s

be like to go blind you probably it’s

be like to go blind you probably it’s very unlikely that you will even be able

very unlikely that you will even be able

very unlikely that you will even be able to find your handbags your heart must be

to find your handbags your heart must be

to find your handbags your heart must be quite broken because that’s it you’re

quite broken because that’s it you’re

quite broken because that’s it you’re not going to see it ever again

not going to see it ever again

not going to see it ever again good good thing for the ladies it’s ok

good good thing for the ladies it’s ok

good good thing for the ladies it’s ok if our clothes are not matching so now

if our clothes are not matching so now

if our clothes are not matching so now imagine how could a soldier cope with

imagine how could a soldier cope with

imagine how could a soldier cope with blindness someone that is not used to

blindness someone that is not used to

blindness someone that is not used to being dependable or anyone someone that

being dependable or anyone someone that

being dependable or anyone someone that always has missions now think about the

always has missions now think about the

always has missions now think about the victims the manchester five days ago all

victims the manchester five days ago all

victims the manchester five days ago all those civilians and many of them will

those civilians and many of them will

those civilians and many of them will have to cope with blindness so that’s

have to cope with blindness so that’s

have to cope with blindness so that’s the first time I came across blind

the first time I came across blind

the first time I came across blind veterans you can be formally known as

veterans you can be formally known as

veterans you can be formally known as st. Dunstan’s it started in 1915 by a

st. Dunstan’s it started in 1915 by a

st. Dunstan’s it started in 1915 by a gentleman called Sir RT person and that

gentleman called Sir RT person and that

gentleman called Sir RT person and that is 102 years ago and he vowed that he

is 102 years ago and he vowed that he

is 102 years ago and he vowed that he was going be the blind man not a blind

was going be the blind man not a blind

was going be the blind man not a blind man and he was going to make sure that

man and he was going to make sure that

man and he was going to make sure that soldiers would live well work have fun

soldiers would live well work have fun

soldiers would live well work have fun play games respect reversed effects of

play games respect reversed effects of

play games respect reversed effects of blindness victory over blindness and you

blindness victory over blindness and you

blindness victory over blindness and you may ask me what do hearts have to do

may ask me what do hearts have to do

may ask me what do hearts have to do with eyes

with eyes

with eyes well actually a lot eyes are highly

well actually a lot eyes are highly

well actually a lot eyes are highly dependent well in good blood vessel

dependent well in good blood vessel

dependent well in good blood vessel integrity just like the heart we need a

integrity just like the heart we need a

integrity just like the heart we need a new blood

new blood

new blood and that’s when I thought I also go in

and that’s when I thought I also go in

and that’s when I thought I also go in to adapt this new system I created by

to adapt this new system I created by

to adapt this new system I created by taking my own blood my own cells and put

taking my own blood my own cells and put

taking my own blood my own cells and put it back to also reverse the effects of

it back to also reverse the effects of

it back to also reverse the effects of blindness try to restore vision and like

blindness try to restore vision and like

blindness try to restore vision and like sir asked you Pearson I want this to be

sir asked you Pearson I want this to be

sir asked you Pearson I want this to be the treatment not a treatment I want us

the treatment not a treatment I want us

the treatment not a treatment I want us to be able to prevent and treat disease

to be able to prevent and treat disease

to be able to prevent and treat disease our methods are very promising

our methods are very promising

our methods are very promising preclinical testing is astounding let me

preclinical testing is astounding let me

preclinical testing is astounding let me tell you something else this whole

tell you something else this whole

tell you something else this whole business of mending broken hearts is so

business of mending broken hearts is so

business of mending broken hearts is so much more than physiological mended is

much more than physiological mended is

much more than physiological mended is more I’m so much more than getting eyes

more I’m so much more than getting eyes

more I’m so much more than getting eyes better and your heart better is also

better and your heart better is also

better and your heart better is also about bringing people together sharing

about bringing people together sharing

about bringing people together sharing information collaboration unity many of

information collaboration unity many of

information collaboration unity many of my friends are also dogs juice also dogs

my friends are also dogs juice also dogs

my friends are also dogs juice also dogs Muslims and we all really work well

Muslims and we all really work well

Muslims and we all really work well together and this highlights the fact

together and this highlights the fact

together and this highlights the fact that the future is highly

that the future is highly

that the future is highly multidisciplinary and the future it is

multidisciplinary and the future it is

multidisciplinary and the future it is right now and you are the future thank

right now and you are the future thank

right now and you are the future thank you

”

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