
avatar being a virtual representation of a human being and in this case it’s a
a human being and in this case it’s a
a human being and in this case it’s a biological representation of the female
biological representation of the female
biological representation of the female reproductive tract so we call it Eva
reproductive tract so we call it Eva
reproductive tract so we call it Eva Tarr so the system that we’ve invented
Tarr so the system that we’ve invented
Tarr so the system that we’ve invented together with Draper laboratories is a
together with Draper laboratories is a
together with Draper laboratories is a series of interconnecting cubes that
series of interconnecting cubes that
series of interconnecting cubes that have individual tubes that now connect
have individual tubes that now connect
have individual tubes that now connect each of the organs so we would have
each of the organs so we would have
each of the organs so we would have actual samples from enough so we would
actual samples from enough so we would
actual samples from enough so we would have like a mouse ovary cultured on one
have like a mouse ovary cultured on one
have like a mouse ovary cultured on one of these strands well the fluid can
of these strands well the fluid can
of these strands well the fluid can dynamically flow between all of these
dynamically flow between all of these
dynamically flow between all of these individual different compartments just
individual different compartments just
individual different compartments just like each of our organs do as if blood
like each of our organs do as if blood
like each of our organs do as if blood was carrying factors between different
was carrying factors between different
was carrying factors between different organs so this would be the ovary so
organs so this would be the ovary so
organs so this would be the ovary so it’s coming from here going into here
it’s coming from here going into here
it’s coming from here going into here and then flowing it’s a little miniature
and then flowing it’s a little miniature
and then flowing it’s a little miniature ovary so you we actually have either the
ovary so you we actually have either the
ovary so you we actually have either the individual follicles from the ovary and
individual follicles from the ovary and
individual follicles from the ovary and a follicle in the ovary are the cells
a follicle in the ovary are the cells
a follicle in the ovary are the cells that make the hormones like estrogen and
that make the hormones like estrogen and
that make the hormones like estrogen and progesterone together with the O site or
progesterone together with the O site or
progesterone together with the O site or we can actually have the entire ovary
we can actually have the entire ovary
we can actually have the entire ovary there and that allows us to control the
there and that allows us to control the
there and that allows us to control the hormones over a 28-day menstrual cycle
hormones over a 28-day menstrual cycle
hormones over a 28-day menstrual cycle in a box so understanding how the uterus
in a box so understanding how the uterus
in a box so understanding how the uterus responds to hormones is really important
responds to hormones is really important
responds to hormones is really important there is no animal model for a lot of
there is no animal model for a lot of
there is no animal model for a lot of the stuff that we study and so the human
the stuff that we study and so the human
the stuff that we study and so the human is really the perfect model to study the
is really the perfect model to study the
is really the perfect model to study the end the human endometrium the uterus and
end the human endometrium the uterus and
end the human endometrium the uterus and the diseases that are associated with it
the diseases that are associated with it
the diseases that are associated with it we were able to actually acquire primary
we were able to actually acquire primary
we were able to actually acquire primary human tissue from women who were having
human tissue from women who were having
human tissue from women who were having surgeries for different minstrel or
surgeries for different minstrel or
surgeries for different minstrel or reproductive related problems this is
reproductive related problems this is
reproductive related problems this is the first time we’ve been able to
the first time we’ve been able to
the first time we’ve been able to model the entire reproductive hormone
model the entire reproductive hormone
model the entire reproductive hormone profile and that profile of menstrual
profile and that profile of menstrual
profile and that profile of menstrual cycle hormones now allows us to connect
cycle hormones now allows us to connect
cycle hormones now allows us to connect those dynamic hormones to downstream
those dynamic hormones to downstream
those dynamic hormones to downstream tissues like the fallopian tube uterus
tissues like the fallopian tube uterus
tissues like the fallopian tube uterus cervix together with a liver and that
cervix together with a liver and that
cervix together with a liver and that integration now will allow us to
integration now will allow us to
integration now will allow us to understand better about the reproductive
understand better about the reproductive
understand better about the reproductive tract itself which we don’t have good
tract itself which we don’t have good
tract itself which we don’t have good models for as well as reproductive
models for as well as reproductive
models for as well as reproductive diseases so now this is going to allow
diseases so now this is going to allow
diseases so now this is going to allow us to test drugs for individuals so
us to test drugs for individuals so
us to test drugs for individuals so we’ll be able to eventually make
we’ll be able to eventually make
we’ll be able to eventually make individual organs from each person so
individual organs from each person so
individual organs from each person so we’ll be able to do personalized
we’ll be able to do personalized
we’ll be able to do personalized medicine it’s really going to open a
medicine it’s really going to open a
medicine it’s really going to open a whole new world of reproductive health
whole new world of reproductive health
whole new world of reproductive health testing
testing
testing [Music]
”
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